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SPIC (Spi-C transcription factor)

Identity

Alias (NCBI)SPI-C
HGNC (Hugo) SPIC
HGNC Alias symbMGC40611
SPI-C
HGNC Previous nameSpi-C transcription factor (Spi-1/PU.1 related)
LocusID (NCBI) 121599
Atlas_Id 47249
Location 12q23.2  [Link to chromosome band 12q23]
Location_base_pair Starts at 101475336 and ends at 101486997 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)SPIC   29549
Cards
Entrez_Gene (NCBI)SPIC  121599  Spi-C transcription factor
AliasesSPI-C
GeneCards (Weizmann)SPIC
Ensembl hg19 (Hinxton)ENSG00000166211 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166211 [Gene_View]  ENSG00000166211 [Sequence]  chr12:101475336-101486997 [Contig_View]  SPIC [Vega]
ICGC DataPortalENSG00000166211
TCGA cBioPortalSPIC
AceView (NCBI)SPIC
Genatlas (Paris)SPIC
WikiGenes121599
SOURCE (Princeton)SPIC
Genetics Home Reference (NIH)SPIC
Genomic and cartography
GoldenPath hg38 (UCSC)SPIC  -     chr12:101475336-101486997 +  12q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPIC  -     12q23.2   [Description]    (hg19-Feb_2009)
GoldenPathSPIC - 12q23.2 [CytoView hg19]  SPIC - 12q23.2 [CytoView hg38]
ImmunoBaseENSG00000166211
genome Data Viewer NCBISPIC [Mapview hg19]  
OMIM612568   
Gene and transcription
Genbank (Entrez)AF518404 BC032317
RefSeq transcript (Entrez)NM_152323
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPIC
Alternative Splicing GalleryENSG00000166211
Gene ExpressionSPIC [ NCBI-GEO ]   SPIC [ EBI - ARRAY_EXPRESS ]   SPIC [ SEEK ]   SPIC [ MEM ]
Gene Expression Viewer (FireBrowse)SPIC [ Firebrowse - Broad ]
GenevisibleExpression of SPIC in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121599
GTEX Portal (Tissue expression)SPIC
Human Protein AtlasENSG00000166211-SPIC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5J4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5J4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5J4
Splice isoforms : SwissVarQ8N5J4
PhosPhoSitePlusQ8N5J4
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)   
Domains : Interpro (EBI)Ets_dom    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Ets (PF00178)   
Domain families : Pfam (NCBI)pfam00178   
Domain families : Smart (EMBL)ETS (SM00413)  
Conserved Domain (NCBI)SPIC
DMDM Disease mutations121599
Blocks (Seattle)SPIC
SuperfamilyQ8N5J4
Human Protein Atlas [tissue]ENSG00000166211-SPIC [tissue]
Peptide AtlasQ8N5J4
HPRD15438
IPIIPI00166862   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5J4
IntAct (EBI)Q8N5J4
FunCoupENSG00000166211
BioGRIDSPIC
STRING (EMBL)SPIC
ZODIACSPIC
Ontologies - Pathways
QuickGOQ8N5J4
Ontology : AmiGOnuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  blastocyst development  nucleus  regulation of transcription by RNA polymerase II  cell differentiation  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBInuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  blastocyst development  nucleus  regulation of transcription by RNA polymerase II  cell differentiation  positive regulation of transcription by RNA polymerase II  
NDEx NetworkSPIC
Atlas of Cancer Signalling NetworkSPIC
Wikipedia pathwaysSPIC
Orthology - Evolution
OrthoDB121599
GeneTree (enSembl)ENSG00000166211
Phylogenetic Trees/Animal Genes : TreeFamSPIC
HOGENOMQ8N5J4
Homologs : HomoloGeneSPIC
Homology/Alignments : Family Browser (UCSC)SPIC
Gene fusions - Rearrangements
Fusion : QuiverSPIC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPIC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPIC
dbVarSPIC
ClinVarSPIC
MonarchSPIC
1000_GenomesSPIC 
Exome Variant ServerSPIC
GNOMAD BrowserENSG00000166211
Varsome BrowserSPIC
Genetic variants : HAPMAP121599
Genomic Variants (DGV)SPIC [DGVbeta]
DECIPHERSPIC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPIC 
Mutations
ICGC Data PortalSPIC 
TCGA Data PortalSPIC 
Broad Tumor PortalSPIC
OASIS PortalSPIC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPIC  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSPIC
Mutations and Diseases : HGMDSPIC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPIC
DgiDB (Drug Gene Interaction Database)SPIC
DoCM (Curated mutations)SPIC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPIC (select a term)
intoGenSPIC
Cancer3DSPIC(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612568   
Orphanet
DisGeNETSPIC
MedgenSPIC
Genetic Testing Registry SPIC
NextProtQ8N5J4 [Medical]
TSGene121599
GENETestsSPIC
Target ValidationSPIC
Huge Navigator SPIC [HugePedia]
snp3D : Map Gene to Disease121599
BioCentury BCIQSPIC
ClinGenSPIC
Clinical trials, drugs, therapy
Protein Interactions : CTD121599
Pharm GKB GenePA134897775
Clinical trialSPIC
Miscellaneous
canSAR (ICR)SPIC (select the gene name)
HarmonizomeSPIC
DataMed IndexSPIC
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPIC
EVEXSPIC
GoPubMedSPIC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:34:05 CEST 2020

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