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SPIN1 (spindlin 1)

Identity

Alias (NCBI)SPIN
TDRD24
HGNC (Hugo) SPIN1
HGNC Alias symbTDRD24
HGNC Previous nameSPIN
HGNC Previous namespindlin
LocusID (NCBI) 10927
Atlas_Id 45690
Location 9q22.1  [Link to chromosome band 9q22]
Location_base_pair Starts at 88388444 and ends at 88478694 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BTC (4q13.3) / SPIN1 (9q22.1)DPYSL2 (8p21.2) / SPIN1 (9q22.1)RGS5 (1q23.3) / SPIN1 (9q22.1)
SPIN1 (9q22.1) / C16orf72 (16p13.2)SPIN1 (9q22.1) / SPIN1 (9q22.1)USP6NL (10p14) / SPIN1 (9q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SPIN1   11243
Cards
Entrez_Gene (NCBI)SPIN1    spindlin 1
AliasesSPIN; TDRD24
GeneCards (Weizmann)SPIN1
Ensembl hg19 (Hinxton)ENSG00000106723 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106723 [Gene_View]  ENSG00000106723 [Sequence]  chr9:88388444-88478694 [Contig_View]  SPIN1 [Vega]
ICGC DataPortalENSG00000106723
TCGA cBioPortalSPIN1
AceView (NCBI)SPIN1
Genatlas (Paris)SPIN1
SOURCE (Princeton)SPIN1
Genetics Home Reference (NIH)SPIN1
Genomic and cartography
GoldenPath hg38 (UCSC)SPIN1  -     chr9:88388444-88478694 +  9q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPIN1  -     9q22.1   [Description]    (hg19-Feb_2009)
GoldenPathSPIN1 - 9q22.1 [CytoView hg19]  SPIN1 - 9q22.1 [CytoView hg38]
ImmunoBaseENSG00000106723
Genome Data Viewer NCBISPIN1 [Mapview hg19]  
OMIM609936   
Gene and transcription
Genbank (Entrez)AF087864 AF106682 AF317228 AJ420427 AK024590
RefSeq transcript (Entrez)NM_006717
Consensus coding sequences : CCDS (NCBI)SPIN1
Gene ExpressionSPIN1 [ NCBI-GEO ]   SPIN1 [ EBI - ARRAY_EXPRESS ]   SPIN1 [ SEEK ]   SPIN1 [ MEM ]
Gene Expression Viewer (FireBrowse)SPIN1 [ Firebrowse - Broad ]
GenevisibleExpression of SPIN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10927
GTEX Portal (Tissue expression)SPIN1
Human Protein AtlasENSG00000106723-SPIN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y657   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y657  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y657
PhosPhoSitePlusQ9Y657
Domains : Interpro (EBI)SPIN/Ssty    SPIN/Ssty_sf    Spindlin-1   
Domain families : Pfam (Sanger)Spin-Ssty (PF02513)   
Domain families : Pfam (NCBI)pfam02513   
Conserved Domain (NCBI)SPIN1
PDB (RSDB)2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
PDB Europe2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
PDB (PDBSum)2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
PDB (IMB)2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
Structural Biology KnowledgeBase2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
SCOP (Structural Classification of Proteins)2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
CATH (Classification of proteins structures)2NS2    4H75    4MZF    4MZG    4MZH    5JSG    5JSJ    5Y5W    6I8B    6I8L    6I8Y    6QPL    7BQZ    7BU9   
SuperfamilyQ9Y657
AlphaFold pdb e-kbQ9Y657   
Human Protein Atlas [tissue]ENSG00000106723-SPIN1 [tissue]
HPRD18096
Protein Interaction databases
DIP (DOE-UCLA)Q9Y657
IntAct (EBI)Q9Y657
BioGRIDSPIN1
STRING (EMBL)SPIN1
ZODIACSPIN1
Ontologies - Pathways
QuickGOQ9Y657
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  cytosol  cytosol  chromatin organization  regulation of transcription, DNA-templated  multicellular organism development  gamete generation  rRNA transcription  Wnt signaling pathway  positive regulation of Wnt signaling pathway  nuclear membrane  methylated histone binding  methylated histone binding  positive regulation of transcription, DNA-templated  meiotic cell cycle  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  cytosol  cytosol  chromatin organization  regulation of transcription, DNA-templated  multicellular organism development  gamete generation  rRNA transcription  Wnt signaling pathway  positive regulation of Wnt signaling pathway  nuclear membrane  methylated histone binding  methylated histone binding  positive regulation of transcription, DNA-templated  meiotic cell cycle  
NDEx NetworkSPIN1
Atlas of Cancer Signalling NetworkSPIN1
Wikipedia pathwaysSPIN1
Orthology - Evolution
OrthoDB10927
GeneTree (enSembl)ENSG00000106723
Phylogenetic Trees/Animal Genes : TreeFamSPIN1
Homologs : HomoloGeneSPIN1
Homology/Alignments : Family Browser (UCSC)SPIN1
Gene fusions - Rearrangements
Fusion : QuiverSPIN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPIN1
dbVarSPIN1
ClinVarSPIN1
MonarchSPIN1
1000_GenomesSPIN1 
Exome Variant ServerSPIN1
GNOMAD BrowserENSG00000106723
Varsome BrowserSPIN1
ACMGSPIN1 variants
VarityQ9Y657
Genomic Variants (DGV)SPIN1 [DGVbeta]
DECIPHERSPIN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPIN1 
Mutations
ICGC Data PortalSPIN1 
TCGA Data PortalSPIN1 
Broad Tumor PortalSPIN1
OASIS PortalSPIN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPIN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSPIN1
Mutations and Diseases : HGMDSPIN1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSPIN1
DgiDB (Drug Gene Interaction Database)SPIN1
DoCM (Curated mutations)SPIN1
CIViC (Clinical Interpretations of Variants in Cancer)SPIN1
Cancer3DSPIN1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609936   
Orphanet
DisGeNETSPIN1
MedgenSPIN1
Genetic Testing Registry SPIN1
NextProtQ9Y657 [Medical]
GENETestsSPIN1
Target ValidationSPIN1
Huge Navigator SPIN1 [HugePedia]
ClinGenSPIN1
Clinical trials, drugs, therapy
MyCancerGenomeSPIN1
Protein Interactions : CTDSPIN1
Pharm GKB GenePA162404504
PharosQ9Y657
Clinical trialSPIN1
Miscellaneous
canSAR (ICR)SPIN1
HarmonizomeSPIN1
DataMed IndexSPIN1
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSPIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:32:54 CEST 2021

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