SPINK5 (serine peptidase inhibitor, Kazal type 5)

Identity

Other names	DKFZp686K19184
	FLJ21544
	FLJ97536
	FLJ97596
	FLJ99794
	LEKTI
	LETKI
	NETS
	NS
	VAKTI
HGNC	SPINK5
Location	5q31-q32
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SPINK5   15464
Entrez_Gene	SPINK5  11005  serine peptidase inhibitor, Kazal type 5
	Cards
GeneCards	SPINK5
Ensembl	SPINK5 [Search_View]   ENSG00000133710 [Gene_View]
Genatlas	SPINK5
GeneLynx	SPINK5
eGenome	SPINK5
euGene	11005
	Genomic and cartography
GoldenPath	SPINK5  -     chr5:147423728-147497118 +  5q33.1   [Description]    (hg18-March_2006)
Ensembl	SPINK5 - 5q33.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SPINK5
	Gene and transcription
Genbank	AF086524 [ ENTREZ ]
Genbank	AF147363 [ ENTREZ ]
Genbank	AI341060 [ ENTREZ ]
Genbank	AJ228139 [ ENTREZ ]
Genbank	AK025197 [ ENTREZ ]
RefSeq	NM_001127698 [ SRS ]    NM_001127698 [ ENTREZ ]
RefSeq	NM_001127699 [ SRS ]    NM_001127699 [ ENTREZ ]
RefSeq	NM_006846 [ SRS ]    NM_006846 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	AC_000137 [ SRS ]    AC_000137 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_029289 [ SRS ]    NT_029289 [ ENTREZ ]
RefSeq	NW_001838953 [ SRS ]    NW_001838953 [ ENTREZ ]
RefSeq	NW_922784 [ SRS ]    NW_922784 [ ENTREZ ]
AceView	SPINK5 AceView - NCBI
Unigene	Hs.331555 [ SRS ]    Hs.331555 [ NCBI ]     HS331555 [ spliceNest ]
Fast-db	11753 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q3LX95 [ SRS]    Q3LX95 [ EXPASY ]     Q3LX95 [ INTERPRO ]     Q3LX95 [ UNIPROT ]
Prosite	PS00282 KAZAL [ SRS ]    PS00282 KAZAL [ Expasy ]
Interpro	IPR002350 Prot_inh_Kazal [ SRS ]    IPR002350 Prot_inh_Kazal [ EBI ]
Interpro	IPR011497 Prot_Inh_Kazal_2 [ SRS ]    IPR011497 Prot_Inh_Kazal_2 [ EBI ]
CluSTr	Q3LX95
Pfam	PF07648 Kazal_2 [ SRS ]    PF07648 Kazal_2 [ Sanger ]    pfam07648 [ NCBI-CDD ]
Smart	SM00280 KAZAL [EMBL]
Blocks	Q3LX95
HPRD	05423
	Protein Interaction databases
DIP	Q3LX95
IntAct	Q3LX95
	Polymorphism : SNP, mutations, diseases
OMIM	147050;256500;605010    [ map ]
GENECLINICS	147050;256500;605010
SNP	SPINK5 [dbSNP-NCBI]
SNP	NM_001127698 [SNP-NCI]
SNP	NM_001127699 [SNP-NCI]
SNP	NM_006846 [SNP-NCI]
SNP	SPINK5 [GeneSNPs - Utah]  SPINK5] [HGBASE - SRS]
HAPMAP	SPINK5 [HAPMAP]
HGMD	SPINK5
	General knowledge
Family Browser	SPINK5 [UCSC Family Browser]
SOURCE	NM_001127698
SOURCE	NM_001127699
SOURCE	NM_006846
SMD	Hs.331555
SAGE	Hs.331555
GO	serine-type endopeptidase inhibitor activity [Amigo]  serine-type endopeptidase inhibitor activity
GO	serine-type endopeptidase inhibitor activity [Amigo]  serine-type endopeptidase inhibitor activity
GO	extracellular region [Amigo]  extracellular region
GO	extracellular region [Amigo]  extracellular region
GO	cytoplasm [Amigo]  cytoplasm
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	endoplasmic reticulum membrane [Amigo]  endoplasmic reticulum membrane
GO	cytosol [Amigo]  cytosol
GO	cell cortex [Amigo]  cell cortex
GO	peptidase activity [Amigo]  peptidase activity
GO	negative regulation of angiogenesis [Amigo]  negative regulation of angiogenesis
GO	extracellular matrix organization and biogenesis [Amigo]  extracellular matrix organization and biogenesis
GO	epithelial cell differentiation [Amigo]  epithelial cell differentiation
GO	hair cell differentiation [Amigo]  hair cell differentiation
GO	lamellar body [Amigo]  lamellar body
GO	anagen [Amigo]  anagen
GO	regulation of T cell differentiation [Amigo]  regulation of T cell differentiation
GO	perinuclear region of cytoplasm [Amigo]  perinuclear region of cytoplasm
GO	negative regulation of immune response [Amigo]  negative regulation of immune response
PubGene	SPINK5
TreeFam	SPINK5
CTD	11005 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SPINK5 Related clones (RZPD - Berlin)
	PubMed
PubMed	32 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:33:09 2008