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SPINK6 (serine peptidase inhibitor, Kazal type 6)

Identity

Alias_namesserine protease inhibitor, Kazal type 6
Alias_symbol (synonym)MGC21394
UNQ844
BUSI2
Other alias
HGNC (Hugo) SPINK6
LocusID (NCBI) 404203
Atlas_Id 74184
Location 5q32  [Link to chromosome band 5q32]
Location_base_pair Starts at 147582357 and ends at 147594700 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FBXO38 (5q32) / SPINK6 (5q32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPINK6   29486
Cards
Entrez_Gene (NCBI)SPINK6  404203  serine peptidase inhibitor, Kazal type 6
AliasesBUSI2; UNQ844
GeneCards (Weizmann)SPINK6
Ensembl hg19 (Hinxton)ENSG00000178172 [Gene_View]  chr5:147582357-147594700 [Contig_View]  SPINK6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000178172 [Gene_View]  chr5:147582357-147594700 [Contig_View]  SPINK6 [Vega]
ICGC DataPortalENSG00000178172
TCGA cBioPortalSPINK6
AceView (NCBI)SPINK6
Genatlas (Paris)SPINK6
WikiGenes404203
SOURCE (Princeton)SPINK6
Genetics Home Reference (NIH)SPINK6
Genomic and cartography
GoldenPath hg19 (UCSC)SPINK6  -     chr5:147582357-147594700 +  5q32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SPINK6  -     5q32   [Description]    (hg38-Dec_2013)
EnsemblSPINK6 - 5q32 [CytoView hg19]  SPINK6 - 5q32 [CytoView hg38]
Mapping of homologs : NCBISPINK6 [Mapview hg19]  SPINK6 [Mapview hg38]
OMIM615868   
Gene and transcription
Genbank (Entrez)AY358716 BC032003 BE122852 GQ504704 GQ504705
RefSeq transcript (Entrez)NM_001195290 NM_205841
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_029289 NW_004929324
Consensus coding sequences : CCDS (NCBI)SPINK6
Cluster EST : UnigeneHs.334274 [ NCBI ]
CGAP (NCI)Hs.334274
Alternative Splicing GalleryENSG00000178172
Gene ExpressionSPINK6 [ NCBI-GEO ]   SPINK6 [ EBI - ARRAY_EXPRESS ]   SPINK6 [ SEEK ]   SPINK6 [ MEM ]
Gene Expression Viewer (FireBrowse)SPINK6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)404203
GTEX Portal (Tissue expression)SPINK6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UWN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UWN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UWN8
Splice isoforms : SwissVarQ6UWN8
PhosPhoSitePlusQ6UWN8
Domaine pattern : Prosite (Expaxy)KAZAL_1 (PS00282)    KAZAL_2 (PS51465)   
Domains : Interpro (EBI)Kazal_dom   
Domain families : Pfam (Sanger)Kazal_1 (PF00050)   
Domain families : Pfam (NCBI)pfam00050   
Domain families : Smart (EMBL)KAZAL (SM00280)  
Conserved Domain (NCBI)SPINK6
DMDM Disease mutations404203
Blocks (Seattle)SPINK6
SuperfamilyQ6UWN8
Human Protein AtlasENSG00000178172
Peptide AtlasQ6UWN8
HPRD15439
IPIIPI00297040   IPI00967463   
Protein Interaction databases
DIP (DOE-UCLA)Q6UWN8
IntAct (EBI)Q6UWN8
FunCoupENSG00000178172
BioGRIDSPINK6
STRING (EMBL)SPINK6
ZODIACSPINK6
Ontologies - Pathways
QuickGOQ6UWN8
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  
NDEx NetworkSPINK6
Atlas of Cancer Signalling NetworkSPINK6
Wikipedia pathwaysSPINK6
Orthology - Evolution
OrthoDB404203
GeneTree (enSembl)ENSG00000178172
Phylogenetic Trees/Animal Genes : TreeFamSPINK6
HOVERGENQ6UWN8
HOGENOMQ6UWN8
Homologs : HomoloGeneSPINK6
Homology/Alignments : Family Browser (UCSC)SPINK6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPINK6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPINK6
dbVarSPINK6
ClinVarSPINK6
1000_GenomesSPINK6 
Exome Variant ServerSPINK6
ExAC (Exome Aggregation Consortium)SPINK6 (select the gene name)
Genetic variants : HAPMAP404203
Genomic Variants (DGV)SPINK6 [DGVbeta]
DECIPHER (Syndromes)5:147582357-147594700  ENSG00000178172
CONAN: Copy Number AnalysisSPINK6 
Mutations
ICGC Data PortalSPINK6 
TCGA Data PortalSPINK6 
Broad Tumor PortalSPINK6
OASIS PortalSPINK6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPINK6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPINK6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPINK6
DgiDB (Drug Gene Interaction Database)SPINK6
DoCM (Curated mutations)SPINK6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPINK6 (select a term)
intoGenSPINK6
Cancer3DSPINK6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615868   
Orphanet
MedgenSPINK6
Genetic Testing Registry SPINK6
NextProtQ6UWN8 [Medical]
TSGene404203
GENETestsSPINK6
Huge Navigator SPINK6 [HugePedia]
snp3D : Map Gene to Disease404203
BioCentury BCIQSPINK6
ClinGenSPINK6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD404203
Chemical/Pharm GKB GenePA134915474
Clinical trialSPINK6
Miscellaneous
canSAR (ICR)SPINK6 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPINK6
EVEXSPINK6
GoPubMedSPINK6
iHOPSPINK6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:46:31 CET 2017

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