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SPINT3 (serine peptidase inhibitor, Kunitz type 3)

Identity

Alias_namesserine protease inhibitor, Kunitz type, 3
Alias_symbol (synonym)HKIB9
Other alias
HGNC (Hugo) SPINT3
LocusID (NCBI) 10816
Atlas_Id 74187
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 45512461 and ends at 45515624 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPINT3   11248
Cards
Entrez_Gene (NCBI)SPINT3  10816  serine peptidase inhibitor, Kunitz type 3
AliasesHKIB9
GeneCards (Weizmann)SPINT3
Ensembl hg19 (Hinxton)ENSG00000101446 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101446 [Gene_View]  chr20:45512461-45515624 [Contig_View]  SPINT3 [Vega]
ICGC DataPortalENSG00000101446
TCGA cBioPortalSPINT3
AceView (NCBI)SPINT3
Genatlas (Paris)SPINT3
WikiGenes10816
SOURCE (Princeton)SPINT3
Genetics Home Reference (NIH)SPINT3
Genomic and cartography
GoldenPath hg38 (UCSC)SPINT3  -     chr20:45512461-45515624 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPINT3  -     20q13.12   [Description]    (hg19-Feb_2009)
EnsemblSPINT3 - 20q13.12 [CytoView hg19]  SPINT3 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBISPINT3 [Mapview hg19]  SPINT3 [Mapview hg38]
OMIM613941   
Gene and transcription
Genbank (Entrez)AY372172 BX088813
RefSeq transcript (Entrez)NM_006652
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPINT3
Cluster EST : UnigeneHs.370724 [ NCBI ]
CGAP (NCI)Hs.370724
Alternative Splicing GalleryENSG00000101446
Gene ExpressionSPINT3 [ NCBI-GEO ]   SPINT3 [ EBI - ARRAY_EXPRESS ]   SPINT3 [ SEEK ]   SPINT3 [ MEM ]
Gene Expression Viewer (FireBrowse)SPINT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10816
GTEX Portal (Tissue expression)SPINT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49223   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49223  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49223
Splice isoforms : SwissVarP49223
PhosPhoSitePlusP49223
Domaine pattern : Prosite (Expaxy)BPTI_KUNITZ_1 (PS00280)    BPTI_KUNITZ_2 (PS50279)   
Domains : Interpro (EBI)Kunitz_BPTI    Prtase_inh_Kunz-CS   
Domain families : Pfam (Sanger)Kunitz_BPTI (PF00014)   
Domain families : Pfam (NCBI)pfam00014   
Domain families : Smart (EMBL)KU (SM00131)  
Conserved Domain (NCBI)SPINT3
DMDM Disease mutations10816
Blocks (Seattle)SPINT3
SuperfamilyP49223
Human Protein AtlasENSG00000101446
Peptide AtlasP49223
IPIIPI00026482   
Protein Interaction databases
DIP (DOE-UCLA)P49223
IntAct (EBI)P49223
FunCoupENSG00000101446
BioGRIDSPINT3
STRING (EMBL)SPINT3
ZODIACSPINT3
Ontologies - Pathways
QuickGOP49223
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  
NDEx NetworkSPINT3
Atlas of Cancer Signalling NetworkSPINT3
Wikipedia pathwaysSPINT3
Orthology - Evolution
OrthoDB10816
GeneTree (enSembl)ENSG00000101446
Phylogenetic Trees/Animal Genes : TreeFamSPINT3
HOVERGENP49223
HOGENOMP49223
Homologs : HomoloGeneSPINT3
Homology/Alignments : Family Browser (UCSC)SPINT3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPINT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPINT3
dbVarSPINT3
ClinVarSPINT3
1000_GenomesSPINT3 
Exome Variant ServerSPINT3
ExAC (Exome Aggregation Consortium)SPINT3 (select the gene name)
Genetic variants : HAPMAP10816
Genomic Variants (DGV)SPINT3 [DGVbeta]
DECIPHERSPINT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPINT3 
Mutations
ICGC Data PortalSPINT3 
TCGA Data PortalSPINT3 
Broad Tumor PortalSPINT3
OASIS PortalSPINT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPINT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPINT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPINT3
DgiDB (Drug Gene Interaction Database)SPINT3
DoCM (Curated mutations)SPINT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPINT3 (select a term)
intoGenSPINT3
Cancer3DSPINT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613941   
Orphanet
MedgenSPINT3
Genetic Testing Registry SPINT3
NextProtP49223 [Medical]
TSGene10816
GENETestsSPINT3
Target ValidationSPINT3
Huge Navigator SPINT3 [HugePedia]
snp3D : Map Gene to Disease10816
BioCentury BCIQSPINT3
ClinGenSPINT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10816
Chemical/Pharm GKB GenePA36078
Clinical trialSPINT3
Miscellaneous
canSAR (ICR)SPINT3 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPINT3
EVEXSPINT3
GoPubMedSPINT3
iHOPSPINT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:40:23 CEST 2017

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