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SPN (sialophorin)

Identity

Alias (NCBI)CD43
GALGP
GPL115
LSN
HGNC (Hugo) SPN
HGNC Alias symbLSN
CD43
GPL115
HGNC Alias nameleukosialin
HGNC Previous namesialophorin (gpL115, leukosialin, CD43)
LocusID (NCBI) 6693
Atlas_Id 43678
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 29663247 and ends at 29670872 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SPN   11249
Cards
Entrez_Gene (NCBI)SPN    sialophorin
AliasesCD43; GALGP; GPL115; LSN
GeneCards (Weizmann)SPN
Ensembl hg19 (Hinxton)ENSG00000197471 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197471 [Gene_View]  ENSG00000197471 [Sequence]  chr16:29663247-29670872 [Contig_View]  SPN [Vega]
ICGC DataPortalENSG00000197471
TCGA cBioPortalSPN
AceView (NCBI)SPN
Genatlas (Paris)SPN
SOURCE (Princeton)SPN
Genetics Home Reference (NIH)SPN
Genomic and cartography
GoldenPath hg38 (UCSC)SPN  -     chr16:29663247-29670872 +  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPN  -     16p11.2   [Description]    (hg19-Feb_2009)
GoldenPathSPN - 16p11.2 [CytoView hg19]  SPN - 16p11.2 [CytoView hg38]
ImmunoBaseENSG00000197471
Genome Data Viewer NCBISPN [Mapview hg19]  
OMIM182160   
Gene and transcription
Genbank (Entrez)AK292626 AK313750 BC012350 BC035510 BQ774811
RefSeq transcript (Entrez)NM_001030288 NM_003123
Consensus coding sequences : CCDS (NCBI)SPN
Gene ExpressionSPN [ NCBI-GEO ]   SPN [ EBI - ARRAY_EXPRESS ]   SPN [ SEEK ]   SPN [ MEM ]
Gene Expression Viewer (FireBrowse)SPN [ Firebrowse - Broad ]
GenevisibleExpression of SPN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6693
GTEX Portal (Tissue expression)SPN
Human Protein AtlasENSG00000197471-SPN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16150   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16150  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16150
PhosPhoSitePlusP16150
Domains : Interpro (EBI)Leukosialin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SPN
SuperfamilyP16150
AlphaFold pdb e-kbP16150   
Human Protein Atlas [tissue]ENSG00000197471-SPN [tissue]
HPRD06770
Protein Interaction databases
DIP (DOE-UCLA)P16150
IntAct (EBI)P16150
BioGRIDSPN
STRING (EMBL)SPN
ZODIACSPN
Ontologies - Pathways
QuickGOP16150
Ontology : AmiGOuropod  T-helper 1 cell lineage commitment  transmembrane signaling receptor activity  protein binding  extracellular space  plasma membrane  integral component of plasma membrane  microvillus  chemotaxis  immune response  cellular defense response  negative regulation of cell adhesion  establishment or maintenance of cell polarity  signal transduction  cell surface receptor signaling pathway  external side of plasma membrane  cell surface  membrane  PML body  Hsp70 protein binding  heat shock protein binding  heat shock protein binding  positive regulation of tumor necrosis factor production  negative regulation of T cell proliferation  defense response to bacterium  defense response to bacterium  regulation of immune response  leukocyte migration  leukocyte tethering or rolling  extracellular exosome  regulation of T cell migration  positive regulation of T cell migration  
Ontology : EGO-EBIuropod  T-helper 1 cell lineage commitment  transmembrane signaling receptor activity  protein binding  extracellular space  plasma membrane  integral component of plasma membrane  microvillus  chemotaxis  immune response  cellular defense response  negative regulation of cell adhesion  establishment or maintenance of cell polarity  signal transduction  cell surface receptor signaling pathway  external side of plasma membrane  cell surface  membrane  PML body  Hsp70 protein binding  heat shock protein binding  heat shock protein binding  positive regulation of tumor necrosis factor production  negative regulation of T cell proliferation  defense response to bacterium  defense response to bacterium  regulation of immune response  leukocyte migration  leukocyte tethering or rolling  extracellular exosome  regulation of T cell migration  positive regulation of T cell migration  
Pathways : KEGGCell adhesion molecules (CAMs)    Epstein-Barr virus infection   
NDEx NetworkSPN
Atlas of Cancer Signalling NetworkSPN
Wikipedia pathwaysSPN
Orthology - Evolution
OrthoDB6693
GeneTree (enSembl)ENSG00000197471
Phylogenetic Trees/Animal Genes : TreeFamSPN
Homologs : HomoloGeneSPN
Homology/Alignments : Family Browser (UCSC)SPN
Gene fusions - Rearrangements
Fusion : QuiverSPN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPN
dbVarSPN
ClinVarSPN
MonarchSPN
1000_GenomesSPN 
Exome Variant ServerSPN
GNOMAD BrowserENSG00000197471
Varsome BrowserSPN
ACMGSPN variants
VarityP16150
Genomic Variants (DGV)SPN [DGVbeta]
DECIPHERSPN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPN 
Mutations
ICGC Data PortalSPN 
TCGA Data PortalSPN 
Broad Tumor PortalSPN
OASIS PortalSPN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSPN
Mutations and Diseases : HGMDSPN
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSPN
DgiDB (Drug Gene Interaction Database)SPN
DoCM (Curated mutations)SPN
CIViC (Clinical Interpretations of Variants in Cancer)SPN
Cancer3DSPN
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182160   
Orphanet
DisGeNETSPN
MedgenSPN
Genetic Testing Registry SPN
NextProtP16150 [Medical]
GENETestsSPN
Target ValidationSPN
Huge Navigator SPN [HugePedia]
ClinGenSPN
Clinical trials, drugs, therapy
MyCancerGenomeSPN
Protein Interactions : CTDSPN
Pharm GKB GenePA36079
PharosP16150
Clinical trialSPN
Miscellaneous
canSAR (ICR)SPN
HarmonizomeSPN
DataMed IndexSPN
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSPN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:32:55 CEST 2021

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