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SPP2 (secreted phosphoprotein 2)

Identity

Alias_namessecreted phosphoprotein 2, 24kD
secreted phosphoprotein 2, 24kDa
Alias_symbol (synonym)SPP24
Other aliasSPP-24
HGNC (Hugo) SPP2
LocusID (NCBI) 6694
Atlas_Id 54665
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 234050702 and ends at 234077132 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DGKD (2q37.1) / SPP2 (2q37.1)SPP2 (2q37.1) / HBG1 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPP2   11256
Cards
Entrez_Gene (NCBI)SPP2  6694  secreted phosphoprotein 2
AliasesSPP-24; SPP24
GeneCards (Weizmann)SPP2
Ensembl hg19 (Hinxton)ENSG00000072080 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000072080 [Gene_View]  chr2:234050702-234077132 [Contig_View]  SPP2 [Vega]
ICGC DataPortalENSG00000072080
TCGA cBioPortalSPP2
AceView (NCBI)SPP2
Genatlas (Paris)SPP2
WikiGenes6694
SOURCE (Princeton)SPP2
Genetics Home Reference (NIH)SPP2
Genomic and cartography
GoldenPath hg38 (UCSC)SPP2  -     chr2:234050702-234077132 +  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPP2  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblSPP2 - 2q37.1 [CytoView hg19]  SPP2 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBISPP2 [Mapview hg19]  SPP2 [Mapview hg38]
OMIM602637   
Gene and transcription
Genbank (Entrez)AJ308099 BC069401 BC106705 BC112438 BC113972
RefSeq transcript (Entrez)NM_006944
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPP2
Cluster EST : UnigeneHs.444488 [ NCBI ]
CGAP (NCI)Hs.444488
Alternative Splicing GalleryENSG00000072080
Gene ExpressionSPP2 [ NCBI-GEO ]   SPP2 [ EBI - ARRAY_EXPRESS ]   SPP2 [ SEEK ]   SPP2 [ MEM ]
Gene Expression Viewer (FireBrowse)SPP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6694
GTEX Portal (Tissue expression)SPP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13103   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13103  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13103
Splice isoforms : SwissVarQ13103
PhosPhoSitePlusQ13103
Domains : Interpro (EBI)Spp-24   
Domain families : Pfam (Sanger)Spp-24 (PF07448)   
Domain families : Pfam (NCBI)pfam07448   
Conserved Domain (NCBI)SPP2
DMDM Disease mutations6694
Blocks (Seattle)SPP2
SuperfamilyQ13103
Human Protein AtlasENSG00000072080
Peptide AtlasQ13103
HPRD04029
IPIIPI00011832   IPI00916734   
Protein Interaction databases
DIP (DOE-UCLA)Q13103
IntAct (EBI)Q13103
FunCoupENSG00000072080
BioGRIDSPP2
STRING (EMBL)SPP2
ZODIACSPP2
Ontologies - Pathways
QuickGOQ13103
Ontology : AmiGOskeletal system development  platelet degranulation  endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  platelet dense granule lumen  bone remodeling  extracellular exosome  
Ontology : EGO-EBIskeletal system development  platelet degranulation  endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  platelet dense granule lumen  bone remodeling  extracellular exosome  
NDEx NetworkSPP2
Atlas of Cancer Signalling NetworkSPP2
Wikipedia pathwaysSPP2
Orthology - Evolution
OrthoDB6694
GeneTree (enSembl)ENSG00000072080
Phylogenetic Trees/Animal Genes : TreeFamSPP2
HOVERGENQ13103
HOGENOMQ13103
Homologs : HomoloGeneSPP2
Homology/Alignments : Family Browser (UCSC)SPP2
Gene fusions - Rearrangements
Fusion : MitelmanDGKD/SPP2 [2q37.1/2q37.1]  [t(2;2)(q37;q37)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPP2
dbVarSPP2
ClinVarSPP2
1000_GenomesSPP2 
Exome Variant ServerSPP2
ExAC (Exome Aggregation Consortium)SPP2 (select the gene name)
Genetic variants : HAPMAP6694
Genomic Variants (DGV)SPP2 [DGVbeta]
DECIPHERSPP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPP2 
Mutations
ICGC Data PortalSPP2 
TCGA Data PortalSPP2 
Broad Tumor PortalSPP2
OASIS PortalSPP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPP2
DgiDB (Drug Gene Interaction Database)SPP2
DoCM (Curated mutations)SPP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPP2 (select a term)
intoGenSPP2
Cancer3DSPP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602637   
Orphanet
MedgenSPP2
Genetic Testing Registry SPP2
NextProtQ13103 [Medical]
TSGene6694
GENETestsSPP2
Huge Navigator SPP2 [HugePedia]
snp3D : Map Gene to Disease6694
BioCentury BCIQSPP2
ClinGenSPP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6694
Chemical/Pharm GKB GenePA36086
Clinical trialSPP2
Miscellaneous
canSAR (ICR)SPP2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPP2
EVEXSPP2
GoPubMedSPP2
iHOPSPP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:38:53 CEST 2017

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