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SPRR2A (small proline rich protein 2A)

Identity

Alias_namessmall proline-rich protein 2A
Other alias-
HGNC (Hugo) SPRR2A
LocusID (NCBI) 6700
Atlas_Id 53219
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 153056120 and ends at 153057512 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANXA2 (15q22.2) / SPRR2A (1q21.3)RHBDF1 (16p13.3) / SPRR2A (1q21.3)SPRR2A (1q21.3) / PCYOX1 (2p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPRR2A   11261
Cards
Entrez_Gene (NCBI)SPRR2A  6700  small proline rich protein 2A
Aliases
GeneCards (Weizmann)SPRR2A
Ensembl hg19 (Hinxton)ENSG00000241794 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000241794 [Gene_View]  chr1:153056120-153057512 [Contig_View]  SPRR2A [Vega]
ICGC DataPortalENSG00000241794
TCGA cBioPortalSPRR2A
AceView (NCBI)SPRR2A
Genatlas (Paris)SPRR2A
WikiGenes6700
SOURCE (Princeton)SPRR2A
Genetics Home Reference (NIH)SPRR2A
Genomic and cartography
GoldenPath hg38 (UCSC)SPRR2A  -     chr1:153056120-153057512 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPRR2A  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblSPRR2A - 1q21.3 [CytoView hg19]  SPRR2A - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBISPRR2A [Mapview hg19]  SPRR2A [Mapview hg38]
OMIM182267   
Gene and transcription
Genbank (Entrez)AK311939 BC096108 BC096109 BC096110 BC096111
RefSeq transcript (Entrez)NM_005988
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPRR2A
Cluster EST : UnigeneHs.355542 [ NCBI ]
CGAP (NCI)Hs.355542
Alternative Splicing GalleryENSG00000241794
Gene ExpressionSPRR2A [ NCBI-GEO ]   SPRR2A [ EBI - ARRAY_EXPRESS ]   SPRR2A [ SEEK ]   SPRR2A [ MEM ]
Gene Expression Viewer (FireBrowse)SPRR2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6700
GTEX Portal (Tissue expression)SPRR2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35326   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP35326  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP35326
Splice isoforms : SwissVarP35326
PhosPhoSitePlusP35326
Domains : Interpro (EBI)SPRR/LCE    SPRR2   
Domain families : Pfam (Sanger)SPRR2 (PF14820)   
Domain families : Pfam (NCBI)pfam14820   
Conserved Domain (NCBI)SPRR2A
DMDM Disease mutations6700
Blocks (Seattle)SPRR2A
SuperfamilyP35326
Human Protein AtlasENSG00000241794
Peptide AtlasP35326
HPRD01649
IPIIPI00017993   
Protein Interaction databases
DIP (DOE-UCLA)P35326
IntAct (EBI)P35326
FunCoupENSG00000241794
BioGRIDSPRR2A
STRING (EMBL)SPRR2A
ZODIACSPRR2A
Ontologies - Pathways
QuickGOP35326
Ontology : AmiGOcornified envelope  cornified envelope  cornified envelope  structural molecule activity  protein binding  cytoplasm  cytosol  epidermis development  peptide cross-linking  keratinocyte differentiation  keratinocyte differentiation  cornification  
Ontology : EGO-EBIcornified envelope  cornified envelope  cornified envelope  structural molecule activity  protein binding  cytoplasm  cytosol  epidermis development  peptide cross-linking  keratinocyte differentiation  keratinocyte differentiation  cornification  
NDEx NetworkSPRR2A
Atlas of Cancer Signalling NetworkSPRR2A
Wikipedia pathwaysSPRR2A
Orthology - Evolution
OrthoDB6700
GeneTree (enSembl)ENSG00000241794
Phylogenetic Trees/Animal Genes : TreeFamSPRR2A
HOVERGENP35326
HOGENOMP35326
Homologs : HomoloGeneSPRR2A
Homology/Alignments : Family Browser (UCSC)SPRR2A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPRR2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPRR2A
dbVarSPRR2A
ClinVarSPRR2A
1000_GenomesSPRR2A 
Exome Variant ServerSPRR2A
ExAC (Exome Aggregation Consortium)SPRR2A (select the gene name)
Genetic variants : HAPMAP6700
Genomic Variants (DGV)SPRR2A [DGVbeta]
DECIPHERSPRR2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPRR2A 
Mutations
ICGC Data PortalSPRR2A 
TCGA Data PortalSPRR2A 
Broad Tumor PortalSPRR2A
OASIS PortalSPRR2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPRR2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPRR2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPRR2A
DgiDB (Drug Gene Interaction Database)SPRR2A
DoCM (Curated mutations)SPRR2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPRR2A (select a term)
intoGenSPRR2A
Cancer3DSPRR2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182267   
Orphanet
MedgenSPRR2A
Genetic Testing Registry SPRR2A
NextProtP35326 [Medical]
TSGene6700
GENETestsSPRR2A
Huge Navigator SPRR2A [HugePedia]
snp3D : Map Gene to Disease6700
BioCentury BCIQSPRR2A
ClinGenSPRR2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6700
Chemical/Pharm GKB GenePA36090
Clinical trialSPRR2A
Miscellaneous
canSAR (ICR)SPRR2A (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPRR2A
EVEXSPRR2A
GoPubMedSPRR2A
iHOPSPRR2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:38:55 CEST 2017

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