Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6700
MIM: 182267
HGNC: 11261
Ensembl: ENSG00000241794
Variants:
dbSNP: 6700
ClinVar: 6700
TCGA: ENSG00000241794
COSMIC: SPRR2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000241794 | ENST00000392653 | P35326 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32908616 | 2020 | Serum Small Proline-Rich Protein 2A (SPRR2A) Is a Noninvasive Biomarker in Gastric Cancer. | 6 |
| 32908616 | 2020 | Serum Small Proline-Rich Protein 2A (SPRR2A) Is a Noninvasive Biomarker in Gastric Cancer. | 6 |
| 30108165 | 2018 | Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. | 17 |
| 30108165 | 2018 | Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease. | 17 |
| 28859701 | 2017 | RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. | 9 |
| 28859701 | 2017 | RNA sequencing and pathway analysis identify tumor necrosis factor alpha driven small proline-rich protein dysregulation in chronic rhinosinusitis. | 9 |
| 24123265 | 2014 | Small proline rich protein 2a in benign and malignant liver disease. | 14 |
| 24123265 | 2014 | Small proline rich protein 2a in benign and malignant liver disease. | 14 |
| 23728799 | 2013 | SPRR2A expression in cholangiocarcinoma increases local tumor invasiveness but prevents metastasis. | 8 |
| 23728799 | 2013 | SPRR2A expression in cholangiocarcinoma increases local tumor invasiveness but prevents metastasis. | 8 |
| 22731250 | 2012 | SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity. | 16 |
| 22731250 | 2012 | SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity. | 16 |
| 18643845 | 2009 | Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. | 17 |
| 18643845 | 2009 | Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. | 17 |
| 18155796 | 2008 | Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes. | 20 |
Citation
Dessen P
SPRR2A (small proline rich protein 2A)
Atlas Genet Cytogenet Oncol Haematol. 2013-03-01
Online version: http://atlasgeneticsoncology.org/gene/53219/sprr2a
