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SPRY3 (sprouty RTK signaling antagonist 3)

Identity

Alias_namessprouty (Drosophila) homolog 2
sprouty homolog 3 (Drosophila)
Alias_symbol (synonym)HSPRY3
Other aliasspry-3
HGNC (Hugo) SPRY3
LocusID (NCBI) 10251
Atlas_Id 74210
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 155612565 and ends at 155782457 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPRY3   11271
Cards
Entrez_Gene (NCBI)SPRY3  10251  sprouty RTK signaling antagonist 3
Aliasesspry-3
GeneCards (Weizmann)SPRY3
Ensembl hg19 (Hinxton)ENSG00000168939 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168939 [Gene_View]  chrX:155612565-155782457 [Contig_View]  SPRY3 [Vega]
ICGC DataPortalENSG00000168939
TCGA cBioPortalSPRY3
AceView (NCBI)SPRY3
Genatlas (Paris)SPRY3
WikiGenes10251
SOURCE (Princeton)SPRY3
Genetics Home Reference (NIH)SPRY3
Genomic and cartography
GoldenPath hg38 (UCSC)SPRY3  -     chrX:155612565-155782457 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPRY3  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblSPRY3 - Xq28 [CytoView hg19]  SPRY3 - Xq28 [CytoView hg38]
Mapping of homologs : NCBISPRY3 [Mapview hg19]  SPRY3 [Mapview hg38]
OMIM300531   
Gene and transcription
Genbank (Entrez)AF041038 AK094610 AK125483 AK289543 AK311508
RefSeq transcript (Entrez)NM_001304990 NM_005840
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPRY3
Cluster EST : UnigeneHs.381912 [ NCBI ]
CGAP (NCI)Hs.381912
Alternative Splicing GalleryENSG00000168939
Gene ExpressionSPRY3 [ NCBI-GEO ]   SPRY3 [ EBI - ARRAY_EXPRESS ]   SPRY3 [ SEEK ]   SPRY3 [ MEM ]
Gene Expression Viewer (FireBrowse)SPRY3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10251
GTEX Portal (Tissue expression)SPRY3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43610   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43610  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43610
Splice isoforms : SwissVarO43610
PhosPhoSitePlusO43610
Domaine pattern : Prosite (Expaxy)SPR (PS51227)   
Domains : Interpro (EBI)Sprouty    SPRY3   
Domain families : Pfam (Sanger)Sprouty (PF05210)   
Domain families : Pfam (NCBI)pfam05210   
Conserved Domain (NCBI)SPRY3
DMDM Disease mutations10251
Blocks (Seattle)SPRY3
SuperfamilyO43610
Human Protein AtlasENSG00000168939
Peptide AtlasO43610
HPRD03917
IPIIPI00013371   IPI00748889   
Protein Interaction databases
DIP (DOE-UCLA)O43610
IntAct (EBI)O43610
FunCoupENSG00000168939
BioGRIDSPRY3
STRING (EMBL)SPRY3
ZODIACSPRY3
Ontologies - Pathways
QuickGOO43610
Ontology : AmiGOmolecular_function  cytoplasm  multicellular organism development  regulation of signal transduction  membrane  axon development  
Ontology : EGO-EBImolecular_function  cytoplasm  multicellular organism development  regulation of signal transduction  membrane  axon development  
Pathways : BIOCARTASprouty regulation of tyrosine kinase signals [Genes]   
NDEx NetworkSPRY3
Atlas of Cancer Signalling NetworkSPRY3
Wikipedia pathwaysSPRY3
Orthology - Evolution
OrthoDB10251
GeneTree (enSembl)ENSG00000168939
Phylogenetic Trees/Animal Genes : TreeFamSPRY3
HOVERGENO43610
HOGENOMO43610
Homologs : HomoloGeneSPRY3
Homology/Alignments : Family Browser (UCSC)SPRY3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPRY3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPRY3
dbVarSPRY3
ClinVarSPRY3
1000_GenomesSPRY3 
Exome Variant ServerSPRY3
ExAC (Exome Aggregation Consortium)SPRY3 (select the gene name)
Genetic variants : HAPMAP10251
Genomic Variants (DGV)SPRY3 [DGVbeta]
DECIPHERSPRY3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPRY3 
Mutations
ICGC Data PortalSPRY3 
TCGA Data PortalSPRY3 
Broad Tumor PortalSPRY3
OASIS PortalSPRY3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSPRY3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPRY3
DgiDB (Drug Gene Interaction Database)SPRY3
DoCM (Curated mutations)SPRY3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPRY3 (select a term)
intoGenSPRY3
Cancer3DSPRY3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300531   
Orphanet
MedgenSPRY3
Genetic Testing Registry SPRY3
NextProtO43610 [Medical]
TSGene10251
GENETestsSPRY3
Target ValidationSPRY3
Huge Navigator SPRY3 [HugePedia]
snp3D : Map Gene to Disease10251
BioCentury BCIQSPRY3
ClinGenSPRY3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10251
Chemical/Pharm GKB GenePA36100
Clinical trialSPRY3
Miscellaneous
canSAR (ICR)SPRY3 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPRY3
EVEXSPRY3
GoPubMedSPRY3
iHOPSPRY3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:44:04 CEST 2017

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