Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SPRYD3 (SPRY domain containing 3)

Identity

Alias_symbol (synonym)FLJ14800
Other alias-
HGNC (Hugo) SPRYD3
LocusID (NCBI) 84926
Atlas_Id 54666
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 53064316 and ends at 53079420 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OS9 (12q13.3) / SPRYD3 (12q13.13)PTDSS1 (8q22.1) / SPRYD3 (12q13.13)SPRYD3 (12q13.13) / FCHSD2 (11q13.4)
SPRYD3 12q13.13 / FCHSD2 11q13.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPRYD3   25920
Cards
Entrez_Gene (NCBI)SPRYD3  84926  SPRY domain containing 3
Aliases
GeneCards (Weizmann)SPRYD3
Ensembl hg19 (Hinxton)ENSG00000167778 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167778 [Gene_View]  chr12:53064316-53079420 [Contig_View]  SPRYD3 [Vega]
ICGC DataPortalENSG00000167778
TCGA cBioPortalSPRYD3
AceView (NCBI)SPRYD3
Genatlas (Paris)SPRYD3
WikiGenes84926
SOURCE (Princeton)SPRYD3
Genetics Home Reference (NIH)SPRYD3
Genomic and cartography
GoldenPath hg38 (UCSC)SPRYD3  -     chr12:53064316-53079420 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPRYD3  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblSPRYD3 - 12q13.13 [CytoView hg19]  SPRYD3 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBISPRYD3 [Mapview hg19]  SPRYD3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF131774 AK027706 AK074566 AK074694 AK294092
RefSeq transcript (Entrez)NM_032840
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPRYD3
Cluster EST : UnigeneHs.343334 [ NCBI ]
CGAP (NCI)Hs.343334
Alternative Splicing GalleryENSG00000167778
Gene ExpressionSPRYD3 [ NCBI-GEO ]   SPRYD3 [ EBI - ARRAY_EXPRESS ]   SPRYD3 [ SEEK ]   SPRYD3 [ MEM ]
Gene Expression Viewer (FireBrowse)SPRYD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84926
GTEX Portal (Tissue expression)SPRYD3
Human Protein AtlasENSG00000167778-SPRYD3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NCJ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NCJ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NCJ5
Splice isoforms : SwissVarQ8NCJ5
PhosPhoSitePlusQ8NCJ5
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)   
Domains : Interpro (EBI)B30.2/SPRY    ConA-like_dom    SPRY_dom   
Domain families : Pfam (Sanger)SPRY (PF00622)   
Domain families : Pfam (NCBI)pfam00622   
Domain families : Smart (EMBL)SPRY (SM00449)  
Conserved Domain (NCBI)SPRYD3
DMDM Disease mutations84926
Blocks (Seattle)SPRYD3
PDB (SRS)2YYO   
PDB (PDBSum)2YYO   
PDB (IMB)2YYO   
PDB (RSDB)2YYO   
Structural Biology KnowledgeBase2YYO   
SCOP (Structural Classification of Proteins)2YYO   
CATH (Classification of proteins structures)2YYO   
SuperfamilyQ8NCJ5
Human Protein Atlas [tissue]ENSG00000167778-SPRYD3 [tissue]
Peptide AtlasQ8NCJ5
HPRD08603
IPIIPI00385992   IPI00922090   IPI01022951   IPI01020678   
Protein Interaction databases
DIP (DOE-UCLA)Q8NCJ5
IntAct (EBI)Q8NCJ5
FunCoupENSG00000167778
BioGRIDSPRYD3
STRING (EMBL)SPRYD3
ZODIACSPRYD3
Ontologies - Pathways
QuickGOQ8NCJ5
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkSPRYD3
Atlas of Cancer Signalling NetworkSPRYD3
Wikipedia pathwaysSPRYD3
Orthology - Evolution
OrthoDB84926
GeneTree (enSembl)ENSG00000167778
Phylogenetic Trees/Animal Genes : TreeFamSPRYD3
HOVERGENQ8NCJ5
HOGENOMQ8NCJ5
Homologs : HomoloGeneSPRYD3
Homology/Alignments : Family Browser (UCSC)SPRYD3
Gene fusions - Rearrangements
Fusion : MitelmanPTDSS1/SPRYD3 [8q22.1/12q13.13]  [t(8;12)(q22;q13)]  
Fusion : MitelmanSPRYD3/FCHSD2 [12q13.13/11q13.4]  [t(11;12)(q13;q13)]  
Fusion: TCGASPRYD3 12q13.13 FCHSD2 11q13.4 LGG
Fusion: Tumor Portal SPRYD3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPRYD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPRYD3
dbVarSPRYD3
ClinVarSPRYD3
1000_GenomesSPRYD3 
Exome Variant ServerSPRYD3
ExAC (Exome Aggregation Consortium)ENSG00000167778
GNOMAD BrowserENSG00000167778
Genetic variants : HAPMAP84926
Genomic Variants (DGV)SPRYD3 [DGVbeta]
DECIPHERSPRYD3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPRYD3 
Mutations
ICGC Data PortalSPRYD3 
TCGA Data PortalSPRYD3 
Broad Tumor PortalSPRYD3
OASIS PortalSPRYD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPRYD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPRYD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPRYD3
DgiDB (Drug Gene Interaction Database)SPRYD3
DoCM (Curated mutations)SPRYD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPRYD3 (select a term)
intoGenSPRYD3
Cancer3DSPRYD3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSPRYD3
Genetic Testing Registry SPRYD3
NextProtQ8NCJ5 [Medical]
TSGene84926
GENETestsSPRYD3
Target ValidationSPRYD3
Huge Navigator SPRYD3 [HugePedia]
snp3D : Map Gene to Disease84926
BioCentury BCIQSPRYD3
ClinGenSPRYD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84926
Chemical/Pharm GKB GenePA143485621
Clinical trialSPRYD3
Miscellaneous
canSAR (ICR)SPRYD3 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPRYD3
EVEXSPRYD3
GoPubMedSPRYD3
iHOPSPRYD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:12:32 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.