SPZ1 (spermatogenic leucine zipper 1)

2017-10-01  

Identity

HGNC
SPZ1
LOCATION
5q14.1
LOCUSID
84654
ALIAS
CILD38,NYD-TSP1,PPP1R148

Other Information

Locus ID:

NCBI: 84654
MIM: 618068
HGNC: 30721
Ensembl: ENSG00000164299

Variants:

dbSNP: 84654
ClinVar: 84654
TCGA: ENSG00000164299
COSMIC: SPZ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164299ENST00000296739Q9BXG8
ENSG00000164299ENST00000296739A0A140VKA5
ENSG00000164299ENST00000511881D6RFL8

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
283684062017Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.6
301544252019TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial-mesenchymal transition and metastasis in liver cancer.4
127783152003Expression of a novel bHLH-Zip gene in human testis.0

Citation

Dessen P

SPZ1 (spermatogenic leucine zipper 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57145/spz1