Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SQLE (squalene epoxidase)

Identity

Other alias-
HGNC (Hugo) SQLE
LocusID (NCBI) 6713
Atlas_Id 47598
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 126010720 and ends at 126034525 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RAI1 (17p11.2) / SQLE (8q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SQLE   11279
Cards
Entrez_Gene (NCBI)SQLE  6713  squalene epoxidase
Aliases
GeneCards (Weizmann)SQLE
Ensembl hg19 (Hinxton)ENSG00000104549 [Gene_View]  chr8:126010720-126034525 [Contig_View]  SQLE [Vega]
Ensembl hg38 (Hinxton)ENSG00000104549 [Gene_View]  chr8:126010720-126034525 [Contig_View]  SQLE [Vega]
ICGC DataPortalENSG00000104549
TCGA cBioPortalSQLE
AceView (NCBI)SQLE
Genatlas (Paris)SQLE
WikiGenes6713
SOURCE (Princeton)SQLE
Genetics Home Reference (NIH)SQLE
Genomic and cartography
GoldenPath hg19 (UCSC)SQLE  -     chr8:126010720-126034525 +  8q24.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SQLE  -     8q24.13   [Description]    (hg38-Dec_2013)
EnsemblSQLE - 8q24.13 [CytoView hg19]  SQLE - 8q24.13 [CytoView hg38]
Mapping of homologs : NCBISQLE [Mapview hg19]  SQLE [Mapview hg38]
OMIM602019   
Gene and transcription
Genbank (Entrez)AF098865 AK055357 AK225085 AK295302 AK301792
RefSeq transcript (Entrez)NM_003129
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)SQLE
Cluster EST : UnigeneHs.71465 [ NCBI ]
CGAP (NCI)Hs.71465
Alternative Splicing GalleryENSG00000104549
Gene ExpressionSQLE [ NCBI-GEO ]   SQLE [ EBI - ARRAY_EXPRESS ]   SQLE [ SEEK ]   SQLE [ MEM ]
Gene Expression Viewer (FireBrowse)SQLE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6713
GTEX Portal (Tissue expression)SQLE
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14534   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14534  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14534
Splice isoforms : SwissVarQ14534
Catalytic activity : Enzyme1.14.14.17 [ Enzyme-Expasy ]   1.14.14.171.14.14.17 [ IntEnz-EBI ]   1.14.14.17 [ BRENDA ]   1.14.14.17 [ KEGG ]   
PhosPhoSitePlusQ14534
Domains : Interpro (EBI)FAD/NAD-binding_dom    Squalene_epoxidase   
Domain families : Pfam (Sanger)SE (PF08491)   
Domain families : Pfam (NCBI)pfam08491   
Conserved Domain (NCBI)SQLE
DMDM Disease mutations6713
Blocks (Seattle)SQLE
SuperfamilyQ14534
Human Protein AtlasENSG00000104549
Peptide AtlasQ14534
HPRD11802
IPIIPI00291544   IPI00978981   IPI00974407   IPI00976058   
Protein Interaction databases
DIP (DOE-UCLA)Q14534
IntAct (EBI)Q14534
FunCoupENSG00000104549
BioGRIDSQLE
STRING (EMBL)SQLE
ZODIACSQLE
Ontologies - Pathways
QuickGOQ14534
Ontology : AmiGOsqualene monooxygenase activity  squalene monooxygenase activity  endoplasmic reticulum membrane  cholesterol biosynthetic process  cellular aromatic compound metabolic process  response to organic substance  integral component of membrane  sterol biosynthetic process  flavin adenine dinucleotide binding  oxidation-reduction process  
Ontology : EGO-EBIsqualene monooxygenase activity  squalene monooxygenase activity  endoplasmic reticulum membrane  cholesterol biosynthetic process  cellular aromatic compound metabolic process  response to organic substance  integral component of membrane  sterol biosynthetic process  flavin adenine dinucleotide binding  oxidation-reduction process  
Pathways : KEGGSteroid biosynthesis   
NDEx NetworkSQLE
Atlas of Cancer Signalling NetworkSQLE
Wikipedia pathwaysSQLE
Orthology - Evolution
OrthoDB6713
GeneTree (enSembl)ENSG00000104549
Phylogenetic Trees/Animal Genes : TreeFamSQLE
HOVERGENQ14534
HOGENOMQ14534
Homologs : HomoloGeneSQLE
Homology/Alignments : Family Browser (UCSC)SQLE
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSQLE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SQLE
dbVarSQLE
ClinVarSQLE
1000_GenomesSQLE 
Exome Variant ServerSQLE
ExAC (Exome Aggregation Consortium)SQLE (select the gene name)
Genetic variants : HAPMAP6713
Genomic Variants (DGV)SQLE [DGVbeta]
DECIPHER (Syndromes)8:126010720-126034525  ENSG00000104549
CONAN: Copy Number AnalysisSQLE 
Mutations
ICGC Data PortalSQLE 
TCGA Data PortalSQLE 
Broad Tumor PortalSQLE
OASIS PortalSQLE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSQLE  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSQLE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SQLE
DgiDB (Drug Gene Interaction Database)SQLE
DoCM (Curated mutations)SQLE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SQLE (select a term)
intoGenSQLE
Cancer3DSQLE(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602019   
Orphanet
MedgenSQLE
Genetic Testing Registry SQLE
NextProtQ14534 [Medical]
TSGene6713
GENETestsSQLE
Huge Navigator SQLE [HugePedia]
snp3D : Map Gene to Disease6713
BioCentury BCIQSQLE
ClinGenSQLE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6713
Chemical/Pharm GKB GenePA36108
Clinical trialSQLE
Miscellaneous
canSAR (ICR)SQLE (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSQLE
EVEXSQLE
GoPubMedSQLE
iHOPSQLE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:20:46 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.