SQOR (sulfide quinone oxidoreductase)

2017-09-01 Affiliation

HGNC

SQOR

LOCATION

15q21.1

LOCUSID

58472

ALIAS

CGI-44,PRO1975,SQR,SQRDL

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 58472
ClinVar: 58472
TCGA: ENSG00000137767
COSMIC: SQOR

Pathway	Source	External ID
Sulfur metabolism	KEGG	ko00920
Sulfur metabolism	KEGG	hsa00920
Metabolism	REACTOME	R-HSA-1430728
Metabolism of amino acids and derivatives	REACTOME	R-HSA-71291
Sulfur amino acid metabolism	REACTOME	R-HSA-1614635
Degradation of cysteine and homocysteine	REACTOME	R-HSA-1614558
Sulfide oxidation to sulfate	REACTOME	R-HSA-1614517

Not detected

Low

Medium

High

Pubmed ID	Year	Title	Citations
22852582	2012	Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite.	80
25225291	2014	Organization of the human mitochondrial hydrogen sulfide oxidation pathway.	67
27856619	2017	CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.	22
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	17
26318450	2015	Transient Kinetic Analysis of Hydrogen Sulfide Oxidation Catalyzed by Human Sulfide Quinone Oxidoreductase.	17
28512131	2017	H₂S oxidation by nanodisc-embedded human sulfide quinone oxidoreductase.	11
26258864	2015	Association of the I264T variant in the sulfide quinone reductase-like (SQRDL) gene with osteoporosis in Korean postmenopausal women.	5
29855663	2018	Genetic susceptibility of postmenopausal osteoporosis on sulfide quinone reductase-like gene.	3
30905673	2019	X-Ray Structure of Human Sulfide:Quinone Oxidoreductase: Insights into the Mechanism of Mitochondrial Hydrogen Sulfide Oxidation.	2

Dessen P

SQOR (sulfide quinone oxidoreductase)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01