Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SRBD1 (S1 RNA binding domain 1)

Identity

Alias_symbol (synonym)FLJ10379
Other alias-
HGNC (Hugo) SRBD1
LocusID (NCBI) 55133
Atlas_Id 51678
Location 2p21  [Link to chromosome band 2p21]
Location_base_pair Starts at 45615819 and ends at 45838433 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ASXL2 (2p23.3) / SRBD1 (2p21)MCFD2 (2p21) / SRBD1 (2p21)SRBD1 (2p21) / CCDC88A (2p16.1)
SRBD1 (2p21) / MTMR7 (8p22)SRBD1 (2p21) / PLEKHA6 (1q32.1)ASXL2 2p23.3 / SRBD1 2p21
MCFD2 2p21 / SRBD1 2p21SRBD1 2p21 / CCDC88A 2p16.1SRBD1 2p21 / PLEKHA6 1q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRBD1   25521
Cards
Entrez_Gene (NCBI)SRBD1  55133  S1 RNA binding domain 1
Aliases
GeneCards (Weizmann)SRBD1
Ensembl hg19 (Hinxton)ENSG00000068784 [Gene_View]  chr2:45615819-45838433 [Contig_View]  SRBD1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000068784 [Gene_View]  chr2:45615819-45838433 [Contig_View]  SRBD1 [Vega]
ICGC DataPortalENSG00000068784
TCGA cBioPortalSRBD1
AceView (NCBI)SRBD1
Genatlas (Paris)SRBD1
WikiGenes55133
SOURCE (Princeton)SRBD1
Genetics Home Reference (NIH)SRBD1
Genomic and cartography
GoldenPath hg19 (UCSC)SRBD1  -     chr2:45615819-45838433 -  2p21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SRBD1  -     2p21   [Description]    (hg38-Dec_2013)
EnsemblSRBD1 - 2p21 [CytoView hg19]  SRBD1 - 2p21 [CytoView hg38]
Mapping of homologs : NCBISRBD1 [Mapview hg19]  SRBD1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK001241 AK055896 AK056536 AK301122 AK316222
RefSeq transcript (Entrez)NM_018079
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)SRBD1
Cluster EST : UnigeneHs.14229 [ NCBI ]
CGAP (NCI)Hs.14229
Alternative Splicing GalleryENSG00000068784
Gene ExpressionSRBD1 [ NCBI-GEO ]   SRBD1 [ EBI - ARRAY_EXPRESS ]   SRBD1 [ SEEK ]   SRBD1 [ MEM ]
Gene Expression Viewer (FireBrowse)SRBD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55133
GTEX Portal (Tissue expression)SRBD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5C6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5C6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5C6
Splice isoforms : SwissVarQ8N5C6
PhosPhoSitePlusQ8N5C6
Domaine pattern : Prosite (Expaxy)S1 (PS50126)   
Domains : Interpro (EBI)NA-bd_OB-fold    RNaseH-like_dom    RuvA_2-like    S1_dom    S1_domain    Tex-like_dom    Tex-like_HTH_dom    Tex-like_N    Tex_RuvX-like_dom    Tex_YqgF    YqgF/RNaseH-like_dom   
Domain families : Pfam (Sanger)S1 (PF00575)    Tex_N (PF09371)    Tex_YqgF (PF16921)   
Domain families : Pfam (NCBI)pfam00575    pfam09371    pfam16921   
Domain families : Smart (EMBL)S1 (SM00316)  YqgFc (SM00732)  
Conserved Domain (NCBI)SRBD1
DMDM Disease mutations55133
Blocks (Seattle)SRBD1
SuperfamilyQ8N5C6
Human Protein AtlasENSG00000068784
Peptide AtlasQ8N5C6
HPRD07669
IPIIPI00171087   IPI00843788   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5C6
IntAct (EBI)Q8N5C6
FunCoupENSG00000068784
BioGRIDSRBD1
STRING (EMBL)SRBD1
ZODIACSRBD1
Ontologies - Pathways
QuickGOQ8N5C6
Ontology : AmiGORNA binding  nucleobase-containing compound metabolic process  
Ontology : EGO-EBIRNA binding  nucleobase-containing compound metabolic process  
NDEx NetworkSRBD1
Atlas of Cancer Signalling NetworkSRBD1
Wikipedia pathwaysSRBD1
Orthology - Evolution
OrthoDB55133
GeneTree (enSembl)ENSG00000068784
Phylogenetic Trees/Animal Genes : TreeFamSRBD1
HOVERGENQ8N5C6
HOGENOMQ8N5C6
Homologs : HomoloGeneSRBD1
Homology/Alignments : Family Browser (UCSC)SRBD1
Gene fusions - Rearrangements
Fusion : MitelmanASXL2/SRBD1 [2p23.3/2p21]  [t(2;2)(p21;p23)]  
Fusion : MitelmanSRBD1/CCDC88A [2p21/2p16.1]  [t(2;2)(p16;p21)]  
Fusion : MitelmanSRBD1/PLEKHA6 [2p21/1q32.1]  [t(1;2)(q32;p21)]  
Fusion: TCGAASXL2 2p23.3 SRBD1 2p21 LUAD
Fusion: TCGAMCFD2 2p21 SRBD1 2p21 BRCA
Fusion: TCGASRBD1 2p21 CCDC88A 2p16.1 BRCA
Fusion: TCGASRBD1 2p21 PLEKHA6 1q32.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRBD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRBD1
dbVarSRBD1
ClinVarSRBD1
1000_GenomesSRBD1 
Exome Variant ServerSRBD1
ExAC (Exome Aggregation Consortium)SRBD1 (select the gene name)
Genetic variants : HAPMAP55133
Genomic Variants (DGV)SRBD1 [DGVbeta]
DECIPHER (Syndromes)2:45615819-45838433  ENSG00000068784
CONAN: Copy Number AnalysisSRBD1 
Mutations
ICGC Data PortalSRBD1 
TCGA Data PortalSRBD1 
Broad Tumor PortalSRBD1
OASIS PortalSRBD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRBD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRBD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRBD1
DgiDB (Drug Gene Interaction Database)SRBD1
DoCM (Curated mutations)SRBD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRBD1 (select a term)
intoGenSRBD1
Cancer3DSRBD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSRBD1
Genetic Testing Registry SRBD1
NextProtQ8N5C6 [Medical]
TSGene55133
GENETestsSRBD1
Huge Navigator SRBD1 [HugePedia]
snp3D : Map Gene to Disease55133
BioCentury BCIQSRBD1
ClinGenSRBD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55133
Chemical/Pharm GKB GenePA144596269
Clinical trialSRBD1
Miscellaneous
canSAR (ICR)SRBD1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRBD1
EVEXSRBD1
GoPubMedSRBD1
iHOPSRBD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:20:47 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.