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SRCAP (Snf2-related CREBBP activator protein)

Identity

Other namesDOMO1
EAF1
FLHS
SWR1
HGNC (Hugo) SRCAP
LocusID (NCBI) 10847
Atlas_Id 43068
Location 16p11.2
Location_base_pair Starts at 30710462 and ends at 30751450 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SRCAP   16974
Cards
Entrez_Gene (NCBI)SRCAP  10847  Snf2-related CREBBP activator protein
GeneCards (Weizmann)SRCAP
Ensembl hg19 (Hinxton)ENSG00000080603 [Gene_View]  chr16:30710462-30751450 [Contig_View]  SRCAP [Vega]
Ensembl hg38 (Hinxton)ENSG00000080603 [Gene_View]  chr16:30710462-30751450 [Contig_View]  SRCAP [Vega]
ICGC DataPortalENSG00000080603
TCGA cBioPortalSRCAP
AceView (NCBI)SRCAP
Genatlas (Paris)SRCAP
WikiGenes10847
SOURCE (Princeton)SRCAP
Genomic and cartography
GoldenPath hg19 (UCSC)SRCAP  -     chr16:30710462-30751450 +  16p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SRCAP  -     16p11.2   [Description]    (hg38-Dec_2013)
EnsemblSRCAP - 16p11.2 [CytoView hg19]  SRCAP - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBISRCAP [Mapview hg19]  SRCAP [Mapview hg38]
OMIM136140   611421   
Gene and transcription
Genbank (Entrez)AB621816 AF143946 AK023808 AK025382 AK126463
RefSeq transcript (Entrez)NM_006662
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_032135 NT_187260 NW_004929400
Consensus coding sequences : CCDS (NCBI)SRCAP
Cluster EST : UnigeneHs.620916 [ NCBI ]
CGAP (NCI)Hs.620916
Alternative Splicing : Fast-db (Paris)GSHG0011117
Alternative Splicing GalleryENSG00000080603
Gene ExpressionSRCAP [ NCBI-GEO ]     SRCAP [ SEEK ]   SRCAP [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZRS2 (Uniprot)
NextProtQ6ZRS2  [Medical]
With graphics : InterProQ6ZRS2
Splice isoforms : SwissVarQ6ZRS2 (Swissvar)
Catalytic activity : Enzyme3.6.4.- [ Enzyme-Expasy ]   3.6.4.-3.6.4.- [ IntEnz-EBI ]   3.6.4.- [ BRENDA ]   3.6.4.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    HSA (PS51204)   
Domains : Interpro (EBI)AT_hook-like    AT_hook_DNA-bd_motif    Helicase/SANT-assoc_DNA-bd    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    SNF2_N   
Related proteins : CluSTrQ6ZRS2
Domain families : Pfam (Sanger)Helicase_C (PF00271)    HSA (PF07529)    SNF2_N (PF00176)   
Domain families : Pfam (NCBI)pfam00271    pfam07529    pfam00176   
Domain families : Smart (EMBL)AT_hook (SM00384)  DEXDc (SM00487)  HELICc (SM00490)  
DMDM Disease mutations10847
Blocks (Seattle)Q6ZRS2
Human Protein AtlasENSG00000080603
Peptide AtlasQ6ZRS2
HPRD18103
IPIIPI00444046   IPI00009101   IPI00550342   IPI00445167   IPI00926983   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZRS2
IntAct (EBI)Q6ZRS2
FunCoupENSG00000080603
BioGRIDSRCAP
IntegromeDBSRCAP
STRING (EMBL)SRCAP
Ontologies - Pathways
QuickGOQ6ZRS2
Ontology : AmiGODNA binding  transcription coactivator activity  helicase activity  histone acetyltransferase activity  protein binding  ATP binding  nucleus  nucleoplasm  Golgi apparatus  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  viral process  histone acetylation  protein complex  perinuclear region of cytoplasm  
Ontology : EGO-EBIDNA binding  transcription coactivator activity  helicase activity  histone acetyltransferase activity  protein binding  ATP binding  nucleus  nucleoplasm  Golgi apparatus  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  viral process  histone acetylation  protein complex  perinuclear region of cytoplasm  
Protein Interaction DatabaseSRCAP
DoCM (Curated mutations)SRCAP
Wikipedia pathwaysSRCAP
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerSRCAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRCAP
dbVarSRCAP
ClinVarSRCAP
1000_GenomesSRCAP 
Exome Variant ServerSRCAP
SNP (GeneSNP Utah)SRCAP
SNP : HGBaseSRCAP
Genetic variants : HAPMAPSRCAP
Genomic Variants (DGV)SRCAP [DGVbeta]
Mutations
ICGC Data PortalSRCAP 
TCGA Data PortalSRCAP 
Tumor PortalSRCAP
Somatic Mutations in Cancer : COSMICSRCAP 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:30710462-30751450
CONAN: Copy Number AnalysisSRCAP 
Mutations and Diseases : HGMDSRCAP
OMIM136140    611421   
MedgenSRCAP
NextProtQ6ZRS2 [Medical]
GENETestsSRCAP
Disease Genetic AssociationSRCAP
Huge Navigator SRCAP [HugePedia]  SRCAP [HugeCancerGEM]
snp3D : Map Gene to Disease10847
DGIdb (Drug Gene Interaction db)SRCAP
General knowledge
Homologs : HomoloGeneSRCAP
Homology/Alignments : Family Browser (UCSC)SRCAP
Phylogenetic Trees/Animal Genes : TreeFamSRCAP
Chemical/Protein Interactions : CTD10847
Chemical/Pharm GKB GenePA162404706
Clinical trialSRCAP
Cancer Resource (Charite)ENSG00000080603
Other databases
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
CoreMineSRCAP
GoPubMedSRCAP
iHOPSRCAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 20:08:35 CEST 2015

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