Identity
HGNC
LOCATION
3p25.3
LOCUSID
ALIAS
ARHGAP14,MEGAP,SRGAP2,WRP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9901
MIM: 606525
HGNC: 19744
Ensembl: ENSG00000196220
Variants:
dbSNP: 9901
ClinVar: 9901
TCGA: ENSG00000196220
COSMIC: SRGAP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196220 | ENST00000360413 | O43295 |
| ENSG00000196220 | ENST00000383836 | O43295 |
| ENSG00000196220 | ENST00000618999 | A0A087WZH4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35205259 | 2022 | C5 and SRGAP3 Polymorphisms Are Linked to Paediatric Allergic Asthma in the Italian Population. | 1 |
| 35205259 | 2022 | C5 and SRGAP3 Polymorphisms Are Linked to Paediatric Allergic Asthma in the Italian Population. | 1 |
| 25819436 | 2015 | A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains. | 8 |
| 25819436 | 2015 | A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains. | 8 |
| 24300292 | 2014 | Interstitial 3p25 deletion in a patient with features of 3p deletion syndrome: further evidence for the role of SRGAP3 in mental retardation. | 4 |
| 24561795 | 2014 | A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1. | 5 |
| 24300292 | 2014 | Interstitial 3p25 deletion in a patient with features of 3p deletion syndrome: further evidence for the role of SRGAP3 in mental retardation. | 4 |
| 24561795 | 2014 | A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1. | 5 |
| 23108406 | 2013 | A tumor suppressor role for srGAP3 in mammary epithelial cells. | 22 |
| 23108406 | 2013 | A tumor suppressor role for srGAP3 in mammary epithelial cells. | 22 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19433673 | 2009 | No association between SRGAP3/MEGAP haploinsufficiency and mental retardation. | 2 |
Citation
Dessen P
SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/53052/srgap3
