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SRMS (src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites)

Identity

Alias_namesC20orf148
chromosome 20 open reading frame 148
Alias_symbol (synonym)SRM
dJ697K14.1
PTK70
Other alias
HGNC (Hugo) SRMS
LocusID (NCBI) 6725
Atlas_Id 43504
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 62171277 and ends at 62178857 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRMS   11298
Cards
Entrez_Gene (NCBI)SRMS  6725  src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
AliasesC20orf148; SRM; dJ697K14.1
GeneCards (Weizmann)SRMS
Ensembl hg19 (Hinxton)ENSG00000125508 [Gene_View]  chr20:62171277-62178857 [Contig_View]  SRMS [Vega]
Ensembl hg38 (Hinxton)ENSG00000125508 [Gene_View]  chr20:62171277-62178857 [Contig_View]  SRMS [Vega]
ICGC DataPortalENSG00000125508
TCGA cBioPortalSRMS
AceView (NCBI)SRMS
Genatlas (Paris)SRMS
WikiGenes6725
SOURCE (Princeton)SRMS
Genetics Home Reference (NIH)SRMS
Genomic and cartography
GoldenPath hg19 (UCSC)SRMS  -     chr20:62171277-62178857 -  20q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SRMS  -     20q13.33   [Description]    (hg38-Dec_2013)
EnsemblSRMS - 20q13.33 [CytoView hg19]  SRMS - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBISRMS [Mapview hg19]  SRMS [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC148643 BC153198
RefSeq transcript (Entrez)NM_080823
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929419
Consensus coding sequences : CCDS (NCBI)SRMS
Alternative Splicing GalleryENSG00000125508
Gene ExpressionSRMS [ NCBI-GEO ]   SRMS [ EBI - ARRAY_EXPRESS ]   SRMS [ SEEK ]   SRMS [ MEM ]
Gene Expression Viewer (FireBrowse)SRMS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6725
GTEX Portal (Tissue expression)SRMS
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3Y6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3Y6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3Y6
Splice isoforms : SwissVarQ9H3Y6
PhosPhoSitePlusQ9H3Y6
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)    SH2 (PS50001)    SH3 (PS50002)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser-Thr/Tyr_kinase_cat_dom    SH2    SH3_domain    Tyr_kinase_AS    Tyr_kinase_cat_dom   
Domain families : Pfam (Sanger)Pkinase_Tyr (PF07714)    SH2 (PF00017)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam07714    pfam00017    pfam14604   
Domain families : Smart (EMBL)SH2 (SM00252)  SH3 (SM00326)  TyrKc (SM00219)  
Conserved Domain (NCBI)SRMS
DMDM Disease mutations6725
Blocks (Seattle)SRMS
SuperfamilyQ9H3Y6
Human Protein AtlasENSG00000125508
Peptide AtlasQ9H3Y6
HPRD10250
IPIIPI00024884   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3Y6
IntAct (EBI)Q9H3Y6
FunCoupENSG00000125508
BioGRIDSRMS
STRING (EMBL)SRMS
ZODIACSRMS
Ontologies - Pathways
QuickGOQ9H3Y6
Ontology : AmiGOprotein tyrosine kinase activity  protein tyrosine kinase activity  non-membrane spanning protein tyrosine kinase activity  receptor binding  protein binding  ATP binding  cytoplasm  cytosol  transmembrane receptor protein tyrosine kinase signaling pathway  negative regulation of signal transduction  cell migration  cell differentiation  extrinsic component of cytoplasmic side of plasma membrane  peptidyl-tyrosine autophosphorylation  regulation of cell proliferation  innate immune response  
Ontology : EGO-EBIprotein tyrosine kinase activity  protein tyrosine kinase activity  non-membrane spanning protein tyrosine kinase activity  receptor binding  protein binding  ATP binding  cytoplasm  cytosol  transmembrane receptor protein tyrosine kinase signaling pathway  negative regulation of signal transduction  cell migration  cell differentiation  extrinsic component of cytoplasmic side of plasma membrane  peptidyl-tyrosine autophosphorylation  regulation of cell proliferation  innate immune response  
NDEx NetworkSRMS
Atlas of Cancer Signalling NetworkSRMS
Wikipedia pathwaysSRMS
Orthology - Evolution
OrthoDB6725
GeneTree (enSembl)ENSG00000125508
Phylogenetic Trees/Animal Genes : TreeFamSRMS
HOVERGENQ9H3Y6
HOGENOMQ9H3Y6
Homologs : HomoloGeneSRMS
Homology/Alignments : Family Browser (UCSC)SRMS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRMS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRMS
dbVarSRMS
ClinVarSRMS
1000_GenomesSRMS 
Exome Variant ServerSRMS
ExAC (Exome Aggregation Consortium)SRMS (select the gene name)
Genetic variants : HAPMAP6725
Genomic Variants (DGV)SRMS [DGVbeta]
DECIPHER (Syndromes)20:62171277-62178857  ENSG00000125508
CONAN: Copy Number AnalysisSRMS 
Mutations
ICGC Data PortalSRMS 
TCGA Data PortalSRMS 
Broad Tumor PortalSRMS
OASIS PortalSRMS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRMS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRMS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRMS
DgiDB (Drug Gene Interaction Database)SRMS
DoCM (Curated mutations)SRMS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRMS (select a term)
intoGenSRMS
Cancer3DSRMS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSRMS
Genetic Testing Registry SRMS
NextProtQ9H3Y6 [Medical]
TSGene6725
GENETestsSRMS
Huge Navigator SRMS [HugePedia]
snp3D : Map Gene to Disease6725
BioCentury BCIQSRMS
ClinGenSRMS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6725
Chemical/Pharm GKB GenePA36122
Clinical trialSRMS
Miscellaneous
canSAR (ICR)SRMS (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRMS
EVEXSRMS
GoPubMedSRMS
iHOPSRMS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:20:49 CEST 2017

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