SRMS (src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites)

2006-10-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
C20orf148,PTK70,SRM,dJ697K14.1

Other Information

Locus ID:

NCBI: 6725
MIM: 617797
HGNC: 11298
Ensembl: ENSG00000125508

Variants:

dbSNP: 6725
ClinVar: 6725
TCGA: ENSG00000125508
COSMIC: SRMS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125508ENST00000217188Q9H3Y6

Expression (GTEx)

0
1
2

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Signaling by the B Cell Receptor (BCR)REACTOMER-HSA-983705
Antigen activates B Cell Receptor (BCR) leading to generation of second messengersREACTOMER-HSA-983695
Signal TransductionREACTOMER-HSA-162582
Signaling by PTK6REACTOMER-HSA-8848021
PTK6 Down-RegulationREACTOMER-HSA-8849472

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
258970812015Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase.15
238220912013The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1.9
294969072018Phosphoproteomics Analysis Identifies Novel Candidate Substrates of the Nonreceptor Tyrosine Kinase, Src-related Kinase Lacking C-terminal Regulatory Tyrosine and N-terminal Myristoylation Sites (SRMS).4

Citation

Dessen P

SRMS (src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43504/srms