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SRPK3 (SRSF protein kinase 3)

Identity

Alias_namesSTK23
serine/threonine kinase 23
SFRS protein kinase 3
Alias_symbol (synonym)MSSK1
Other aliasMSSK-1
HGNC (Hugo) SRPK3
LocusID (NCBI) 26576
Atlas_Id 55179
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153781001 and ends at 153785732 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRPK3   11402
Cards
Entrez_Gene (NCBI)SRPK3  26576  SRSF protein kinase 3
AliasesMSSK-1; MSSK1; STK23
GeneCards (Weizmann)SRPK3
Ensembl hg19 (Hinxton)ENSG00000184343 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184343 [Gene_View]  chrX:153781001-153785732 [Contig_View]  SRPK3 [Vega]
ICGC DataPortalENSG00000184343
TCGA cBioPortalSRPK3
AceView (NCBI)SRPK3
Genatlas (Paris)SRPK3
WikiGenes26576
SOURCE (Princeton)SRPK3
Genetics Home Reference (NIH)SRPK3
Genomic and cartography
GoldenPath hg38 (UCSC)SRPK3  -     chrX:153781001-153785732 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRPK3  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblSRPK3 - Xq28 [CytoView hg19]  SRPK3 - Xq28 [CytoView hg38]
Mapping of homologs : NCBISRPK3 [Mapview hg19]  SRPK3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF027406 AK301749 AK314828 BC092416 BC117124
RefSeq transcript (Entrez)NM_001170760 NM_001170761 NM_014370
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRPK3
Cluster EST : UnigeneHs.104865 [ NCBI ]
CGAP (NCI)Hs.104865
Alternative Splicing GalleryENSG00000184343
Gene ExpressionSRPK3 [ NCBI-GEO ]   SRPK3 [ EBI - ARRAY_EXPRESS ]   SRPK3 [ SEEK ]   SRPK3 [ MEM ]
Gene Expression Viewer (FireBrowse)SRPK3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26576
GTEX Portal (Tissue expression)SRPK3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPE1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPE1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPE1
Splice isoforms : SwissVarQ9UPE1
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ9UPE1
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)SRPK3
DMDM Disease mutations26576
Blocks (Seattle)SRPK3
SuperfamilyQ9UPE1
Human Protein AtlasENSG00000184343
Peptide AtlasQ9UPE1
HPRD06731
IPIIPI00936551   IPI00946650   IPI00921386   IPI00010067   IPI00645935   IPI00645372   IPI01012083   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPE1
IntAct (EBI)Q9UPE1
FunCoupENSG00000184343
BioGRIDSRPK3
STRING (EMBL)SRPK3
ZODIACSRPK3
Ontologies - Pathways
QuickGOQ9UPE1
Ontology : AmiGOspliceosomal complex assembly  protein serine/threonine kinase activity  protein binding  ATP binding  cellular_component  nucleus  cytoplasm  protein phosphorylation  skeletal muscle tissue development  cell differentiation  intracellular signal transduction  regulation of mRNA processing  muscle tissue development  
Ontology : EGO-EBIspliceosomal complex assembly  protein serine/threonine kinase activity  protein binding  ATP binding  cellular_component  nucleus  cytoplasm  protein phosphorylation  skeletal muscle tissue development  cell differentiation  intracellular signal transduction  regulation of mRNA processing  muscle tissue development  
NDEx NetworkSRPK3
Atlas of Cancer Signalling NetworkSRPK3
Wikipedia pathwaysSRPK3
Orthology - Evolution
OrthoDB26576
GeneTree (enSembl)ENSG00000184343
Phylogenetic Trees/Animal Genes : TreeFamSRPK3
HOVERGENQ9UPE1
HOGENOMQ9UPE1
Homologs : HomoloGeneSRPK3
Homology/Alignments : Family Browser (UCSC)SRPK3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRPK3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRPK3
dbVarSRPK3
ClinVarSRPK3
1000_GenomesSRPK3 
Exome Variant ServerSRPK3
ExAC (Exome Aggregation Consortium)SRPK3 (select the gene name)
Genetic variants : HAPMAP26576
Genomic Variants (DGV)SRPK3 [DGVbeta]
DECIPHERSRPK3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRPK3 
Mutations
ICGC Data PortalSRPK3 
TCGA Data PortalSRPK3 
Broad Tumor PortalSRPK3
OASIS PortalSRPK3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRPK3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRPK3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch SRPK3
DgiDB (Drug Gene Interaction Database)SRPK3
DoCM (Curated mutations)SRPK3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRPK3 (select a term)
intoGenSRPK3
Cancer3DSRPK3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSRPK3
Genetic Testing Registry SRPK3
NextProtQ9UPE1 [Medical]
TSGene26576
GENETestsSRPK3
Target ValidationSRPK3
Huge Navigator SRPK3 [HugePedia]
snp3D : Map Gene to Disease26576
BioCentury BCIQSRPK3
ClinGenSRPK3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26576
Chemical/Pharm GKB GenePA162404805
Clinical trialSRPK3
Miscellaneous
canSAR (ICR)SRPK3 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRPK3
EVEXSRPK3
GoPubMedSRPK3
iHOPSRPK3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:57:25 CEST 2017

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