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SRPRB (SRP receptor beta subunit)

Identity

Alias_namessignal recognition particle receptor
Alias_symbol (synonym)APMCF1
SR-beta
Other alias
HGNC (Hugo) SRPRB
LocusID (NCBI) 58477
Atlas_Id 45781
Location 3q22.1  [Link to chromosome band 3q22]
Location_base_pair Starts at 133502877 and ends at 133540336 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SRPRB (3q22.1) / SRPRB (3q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRPRB   24085
Cards
Entrez_Gene (NCBI)SRPRB  58477  SRP receptor beta subunit
AliasesAPMCF1
GeneCards (Weizmann)SRPRB
Ensembl hg19 (Hinxton)ENSG00000144867 [Gene_View]  chr3:133502877-133540336 [Contig_View]  SRPRB [Vega]
Ensembl hg38 (Hinxton)ENSG00000144867 [Gene_View]  chr3:133502877-133540336 [Contig_View]  SRPRB [Vega]
ICGC DataPortalENSG00000144867
TCGA cBioPortalSRPRB
AceView (NCBI)SRPRB
Genatlas (Paris)SRPRB
WikiGenes58477
SOURCE (Princeton)SRPRB
Genetics Home Reference (NIH)SRPRB
Genomic and cartography
GoldenPath hg19 (UCSC)SRPRB  -     chr3:133502877-133540336 +  3q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SRPRB  -     3q22.1   [Description]    (hg38-Dec_2013)
EnsemblSRPRB - 3q22.1 [CytoView hg19]  SRPRB - 3q22.1 [CytoView hg38]
Mapping of homologs : NCBISRPRB [Mapview hg19]  SRPRB [Mapview hg38]
OMIM616883   
Gene and transcription
Genbank (Entrez)AF086914 AF141882 AK027307 AK027525 AK075531
RefSeq transcript (Entrez)NM_021203
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)SRPRB
Cluster EST : UnigeneHs.12152 [ NCBI ]
CGAP (NCI)Hs.12152
Alternative Splicing GalleryENSG00000144867
Gene ExpressionSRPRB [ NCBI-GEO ]   SRPRB [ EBI - ARRAY_EXPRESS ]   SRPRB [ SEEK ]   SRPRB [ MEM ]
Gene Expression Viewer (FireBrowse)SRPRB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58477
GTEX Portal (Tissue expression)SRPRB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5M8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5M8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5M8
Splice isoforms : SwissVarQ9Y5M8
PhosPhoSitePlusQ9Y5M8
Domains : Interpro (EBI)P-loop_NTPase    Small_GTPase_ARF    SRP_receptor_beta_su   
Domain families : Pfam (Sanger)SRPRB (PF09439)   
Domain families : Pfam (NCBI)pfam09439   
Conserved Domain (NCBI)SRPRB
DMDM Disease mutations58477
Blocks (Seattle)SRPRB
SuperfamilyQ9Y5M8
Human Protein AtlasENSG00000144867
Peptide AtlasQ9Y5M8
HPRD18105
IPIIPI00295098   IPI00947333   IPI00797747   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5M8
IntAct (EBI)Q9Y5M8
FunCoupENSG00000144867
BioGRIDSRPRB
STRING (EMBL)SRPRB
ZODIACSRPRB
Ontologies - Pathways
QuickGOQ9Y5M8
Ontology : AmiGOsignal recognition particle binding  GTP binding  cytoplasm  signal recognition particle receptor complex  endoplasmic reticulum membrane  cytoplasmic microtubule  SRP-dependent cotranslational protein targeting to membrane  small GTPase mediated signal transduction  membrane  integral component of membrane  IRE1-mediated unfolded protein response  
Ontology : EGO-EBIsignal recognition particle binding  GTP binding  cytoplasm  signal recognition particle receptor complex  endoplasmic reticulum membrane  cytoplasmic microtubule  SRP-dependent cotranslational protein targeting to membrane  small GTPase mediated signal transduction  membrane  integral component of membrane  IRE1-mediated unfolded protein response  
Pathways : KEGGProtein export   
NDEx NetworkSRPRB
Atlas of Cancer Signalling NetworkSRPRB
Wikipedia pathwaysSRPRB
Orthology - Evolution
OrthoDB58477
GeneTree (enSembl)ENSG00000144867
Phylogenetic Trees/Animal Genes : TreeFamSRPRB
HOVERGENQ9Y5M8
HOGENOMQ9Y5M8
Homologs : HomoloGeneSRPRB
Homology/Alignments : Family Browser (UCSC)SRPRB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRPRB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRPRB
dbVarSRPRB
ClinVarSRPRB
1000_GenomesSRPRB 
Exome Variant ServerSRPRB
ExAC (Exome Aggregation Consortium)SRPRB (select the gene name)
Genetic variants : HAPMAP58477
Genomic Variants (DGV)SRPRB [DGVbeta]
DECIPHER (Syndromes)3:133502877-133540336  ENSG00000144867
CONAN: Copy Number AnalysisSRPRB 
Mutations
ICGC Data PortalSRPRB 
TCGA Data PortalSRPRB 
Broad Tumor PortalSRPRB
OASIS PortalSRPRB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRPRB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRPRB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRPRB
DgiDB (Drug Gene Interaction Database)SRPRB
DoCM (Curated mutations)SRPRB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRPRB (select a term)
intoGenSRPRB
Cancer3DSRPRB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616883   
Orphanet
MedgenSRPRB
Genetic Testing Registry SRPRB
NextProtQ9Y5M8 [Medical]
TSGene58477
GENETestsSRPRB
Huge Navigator SRPRB [HugePedia]
snp3D : Map Gene to Disease58477
BioCentury BCIQSRPRB
ClinGenSRPRB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD58477
Chemical/Pharm GKB GenePA128394701
Clinical trialSRPRB
Miscellaneous
canSAR (ICR)SRPRB (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRPRB
EVEXSRPRB
GoPubMedSRPRB
iHOPSRPRB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:20:51 CEST 2017

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