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SRR (serine racemase)

Identity

Alias_symbol (synonym)ILV1
ISO1
Other alias
HGNC (Hugo) SRR
LocusID (NCBI) 63826
Atlas_Id 55906
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 2303943 and ends at 2325264 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FUS (16p11.2) / SRR (17p13.3)SRR (17p13.3) / ROMO1 (20q11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRR   14398
Cards
Entrez_Gene (NCBI)SRR  63826  serine racemase
AliasesILV1; ISO1
GeneCards (Weizmann)SRR
Ensembl hg19 (Hinxton)ENSG00000167720 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167720 [Gene_View]  chr17:2303943-2325264 [Contig_View]  SRR [Vega]
ICGC DataPortalENSG00000167720
TCGA cBioPortalSRR
AceView (NCBI)SRR
Genatlas (Paris)SRR
WikiGenes63826
SOURCE (Princeton)SRR
Genetics Home Reference (NIH)SRR
Genomic and cartography
GoldenPath hg38 (UCSC)SRR  -     chr17:2303943-2325264 +  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRR  -     17p13.3   [Description]    (hg19-Feb_2009)
EnsemblSRR - 17p13.3 [CytoView hg19]  SRR - 17p13.3 [CytoView hg38]
Mapping of homologs : NCBISRR [Mapview hg19]  SRR [Mapview hg38]
OMIM606477   
Gene and transcription
Genbank (Entrez)AF169974 AI952697 AK023169 AK223120 AL834378
RefSeq transcript (Entrez)NM_001304803 NM_021947
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRR
Cluster EST : UnigeneHs.461954 [ NCBI ]
CGAP (NCI)Hs.461954
Alternative Splicing GalleryENSG00000167720
Gene ExpressionSRR [ NCBI-GEO ]   SRR [ EBI - ARRAY_EXPRESS ]   SRR [ SEEK ]   SRR [ MEM ]
Gene Expression Viewer (FireBrowse)SRR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63826
GTEX Portal (Tissue expression)SRR
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZT4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZT4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZT4
Splice isoforms : SwissVarQ9GZT4
PhosPhoSitePlusQ9GZT4
Domaine pattern : Prosite (Expaxy)DEHYDRATASE_SER_THR (PS00165)   
Domains : Interpro (EBI)Ser/Thr_deHydtase_PyrdxlP-BS    TrpB-like_PLP-dep   
Domain families : Pfam (Sanger)PALP (PF00291)   
Domain families : Pfam (NCBI)pfam00291   
Conserved Domain (NCBI)SRR
DMDM Disease mutations63826
Blocks (Seattle)SRR
PDB (SRS)3L6B    3L6R   
PDB (PDBSum)3L6B    3L6R   
PDB (IMB)3L6B    3L6R   
PDB (RSDB)3L6B    3L6R   
Structural Biology KnowledgeBase3L6B    3L6R   
SCOP (Structural Classification of Proteins)3L6B    3L6R   
CATH (Classification of proteins structures)3L6B    3L6R   
SuperfamilyQ9GZT4
Human Protein AtlasENSG00000167720
Peptide AtlasQ9GZT4
HPRD10451
IPIIPI00030328   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZT4
IntAct (EBI)Q9GZT4
FunCoupENSG00000167720
BioGRIDSRR
STRING (EMBL)SRR
ZODIACSRR
Ontologies - Pathways
QuickGOQ9GZT4
Ontology : AmiGOmagnesium ion binding  L-serine ammonia-lyase activity  calcium ion binding  ATP binding  ATP binding  cytoplasm  plasma membrane  L-serine metabolic process  brain development  aging  D-serine ammonia-lyase activity  serine family amino acid metabolic process  glycine binding  threonine racemase activity  PDZ domain binding  pyridoxal phosphate binding  pyridoxal phosphate binding  serine racemase activity  response to lipopolysaccharide  response to drug  protein homodimerization activity  protein homodimerization activity  pyruvate biosynthetic process  neuronal cell body  response to morphine  apical part of cell  protein homotetramerization  D-serine metabolic process  D-serine biosynthetic process  
Ontology : EGO-EBImagnesium ion binding  L-serine ammonia-lyase activity  calcium ion binding  ATP binding  ATP binding  cytoplasm  plasma membrane  L-serine metabolic process  brain development  aging  D-serine ammonia-lyase activity  serine family amino acid metabolic process  glycine binding  threonine racemase activity  PDZ domain binding  pyridoxal phosphate binding  pyridoxal phosphate binding  serine racemase activity  response to lipopolysaccharide  response to drug  protein homodimerization activity  protein homodimerization activity  pyruvate biosynthetic process  neuronal cell body  response to morphine  apical part of cell  protein homotetramerization  D-serine metabolic process  D-serine biosynthetic process  
Pathways : KEGGGlycine, serine and threonine metabolism   
NDEx NetworkSRR
Atlas of Cancer Signalling NetworkSRR
Wikipedia pathwaysSRR
Orthology - Evolution
OrthoDB63826
GeneTree (enSembl)ENSG00000167720
Phylogenetic Trees/Animal Genes : TreeFamSRR
HOVERGENQ9GZT4
HOGENOMQ9GZT4
Homologs : HomoloGeneSRR
Homology/Alignments : Family Browser (UCSC)SRR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRR
dbVarSRR
ClinVarSRR
1000_GenomesSRR 
Exome Variant ServerSRR
ExAC (Exome Aggregation Consortium)SRR (select the gene name)
Genetic variants : HAPMAP63826
Genomic Variants (DGV)SRR [DGVbeta]
DECIPHERSRR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRR 
Mutations
ICGC Data PortalSRR 
TCGA Data PortalSRR 
Broad Tumor PortalSRR
OASIS PortalSRR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRR
DgiDB (Drug Gene Interaction Database)SRR
DoCM (Curated mutations)SRR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRR (select a term)
intoGenSRR
Cancer3DSRR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606477   
Orphanet
MedgenSRR
Genetic Testing Registry SRR
NextProtQ9GZT4 [Medical]
TSGene63826
GENETestsSRR
Target ValidationSRR
Huge Navigator SRR [HugePedia]
snp3D : Map Gene to Disease63826
BioCentury BCIQSRR
ClinGenSRR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63826
Chemical/Pharm GKB GenePA37877
Clinical trialSRR
Miscellaneous
canSAR (ICR)SRR (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRR
EVEXSRR
GoPubMedSRR
iHOPSRR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 25 19:33:02 CEST 2017

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