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SRRM4 (serine/arginine repetitive matrix 4)

Identity

Alias_namesKIAA1853
KIAA1853
Alias_symbol (synonym)nSR100
Other aliasMU-MB-2.76
HGNC (Hugo) SRRM4
LocusID (NCBI) 84530
Atlas_Id 53931
Location 12q24.23  [Link to chromosome band 12q24]
Location_base_pair Starts at 118981495 and ends at 119163051 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C12orf49 (12q24.22) / SRRM4 (12q24.23)HECTD4 (12q24.13) / SRRM4 (12q24.23)SEMA5A (5p15.31) / SRRM4 (12q24.23)
C12orf49 12q24.22 / SRRM4 12q24.23C12orf51 SRRM4 12q24.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRRM4   29389
Cards
Entrez_Gene (NCBI)SRRM4  84530  serine/arginine repetitive matrix 4
AliasesKIAA1853; MU-MB-2.76; nSR100
GeneCards (Weizmann)SRRM4
Ensembl hg19 (Hinxton)ENSG00000139767 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139767 [Gene_View]  chr12:118981495-119163051 [Contig_View]  SRRM4 [Vega]
ICGC DataPortalENSG00000139767
TCGA cBioPortalSRRM4
AceView (NCBI)SRRM4
Genatlas (Paris)SRRM4
WikiGenes84530
SOURCE (Princeton)SRRM4
Genetics Home Reference (NIH)SRRM4
Genomic and cartography
GoldenPath hg38 (UCSC)SRRM4  -     chr12:118981495-119163051 +  12q24.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRRM4  -     12q24.23   [Description]    (hg19-Feb_2009)
EnsemblSRRM4 - 12q24.23 [CytoView hg19]  SRRM4 - 12q24.23 [CytoView hg38]
Mapping of homologs : NCBISRRM4 [Mapview hg19]  SRRM4 [Mapview hg38]
OMIM613103   
Gene and transcription
Genbank (Entrez)AB058756 AK055717 AK125400 AK291361 AY130006
RefSeq transcript (Entrez)NM_194286
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRRM4
Cluster EST : UnigeneHs.744964 [ NCBI ]
CGAP (NCI)Hs.744964
Alternative Splicing GalleryENSG00000139767
Gene ExpressionSRRM4 [ NCBI-GEO ]   SRRM4 [ EBI - ARRAY_EXPRESS ]   SRRM4 [ SEEK ]   SRRM4 [ MEM ]
Gene Expression Viewer (FireBrowse)SRRM4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84530
GTEX Portal (Tissue expression)SRRM4
Protein : pattern, domain, 3D structure
UniProt/SwissProtA7MD48   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA7MD48  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA7MD48
Splice isoforms : SwissVarA7MD48
PhosPhoSitePlusA7MD48
Domains : Interpro (EBI)SRRM_C   
Domain families : Pfam (Sanger)SRRM_C (PF15230)   
Domain families : Pfam (NCBI)pfam15230   
Conserved Domain (NCBI)SRRM4
DMDM Disease mutations84530
Blocks (Seattle)SRRM4
SuperfamilyA7MD48
Human Protein AtlasENSG00000139767
Peptide AtlasA7MD48
HPRD13897
IPIIPI00186554   
Protein Interaction databases
DIP (DOE-UCLA)A7MD48
IntAct (EBI)A7MD48
FunCoupENSG00000139767
BioGRIDSRRM4
STRING (EMBL)SRRM4
ZODIACSRRM4
Ontologies - Pathways
QuickGOA7MD48
Ontology : AmiGOregulation of alternative mRNA splicing, via spliceosome  mRNA binding  nucleus  mRNA processing  nervous system development  sensory perception of sound  RNA splicing  cell differentiation  regulation of RNA splicing  
Ontology : EGO-EBIregulation of alternative mRNA splicing, via spliceosome  mRNA binding  nucleus  mRNA processing  nervous system development  sensory perception of sound  RNA splicing  cell differentiation  regulation of RNA splicing  
NDEx NetworkSRRM4
Atlas of Cancer Signalling NetworkSRRM4
Wikipedia pathwaysSRRM4
Orthology - Evolution
OrthoDB84530
GeneTree (enSembl)ENSG00000139767
Phylogenetic Trees/Animal Genes : TreeFamSRRM4
HOVERGENA7MD48
HOGENOMA7MD48
Homologs : HomoloGeneSRRM4
Homology/Alignments : Family Browser (UCSC)SRRM4
Gene fusions - Rearrangements
Fusion : MitelmanC12orf49/SRRM4 [12q24.22/12q24.23]  [t(12;12)(q24;q24)]  
Fusion : MitelmanHECTD4/SRRM4 [12q24.13/12q24.23]  [t(12;12)(q24;q24)]  
Fusion : MitelmanXRCC6BP1/SRRM4 [12q14.1/12q24.23]  [t(12;12)(q14;q24)]  
Fusion: TCGAC12orf49 12q24.22 SRRM4 12q24.23 GBM
Fusion: TCGAC12orf51 SRRM4 12q24.23 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRRM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRRM4
dbVarSRRM4
ClinVarSRRM4
1000_GenomesSRRM4 
Exome Variant ServerSRRM4
ExAC (Exome Aggregation Consortium)SRRM4 (select the gene name)
Genetic variants : HAPMAP84530
Genomic Variants (DGV)SRRM4 [DGVbeta]
DECIPHERSRRM4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRRM4 
Mutations
ICGC Data PortalSRRM4 
TCGA Data PortalSRRM4 
Broad Tumor PortalSRRM4
OASIS PortalSRRM4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRRM4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRRM4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRRM4
DgiDB (Drug Gene Interaction Database)SRRM4
DoCM (Curated mutations)SRRM4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRRM4 (select a term)
intoGenSRRM4
Cancer3DSRRM4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613103   
Orphanet
MedgenSRRM4
Genetic Testing Registry SRRM4
NextProtA7MD48 [Medical]
TSGene84530
GENETestsSRRM4
Huge Navigator SRRM4 [HugePedia]
snp3D : Map Gene to Disease84530
BioCentury BCIQSRRM4
ClinGenSRRM4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84530
Chemical/Pharm GKB GenePA165513415
Clinical trialSRRM4
Miscellaneous
canSAR (ICR)SRRM4 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRRM4
EVEXSRRM4
GoPubMedSRRM4
iHOPSRRM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:39:07 CEST 2017

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