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SRRT (serrate, RNA effector molecule)

Identity

Alias_namesserrate RNA effector molecule homolog (Arabidopsis)
Alias_symbol (synonym)Asr2
serrate
ARS2
Other aliasASR2
HGNC (Hugo) SRRT
LocusID (NCBI) 51593
Atlas_Id 53328
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 100875079 and ends at 100888664 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KIAA1462 (10p11.23) / SRRT (7q22.1)POLR2H (3q27.1) / SRRT (7q22.1)SNHG12 (1p35.3) / SRRT (7q22.1)
SRRT (7q22.1) / ATP5G3 (2q31.1)SRRT (7q22.1) / GAPDH (12p13.31)SRRT (7q22.1) / PPP1R17 (7p14.3)
SRRT (7q22.1) / SRRT (7q22.1)SRRT (7q22.1) / TRIP6 (7q22.1)SRRT 7q22.1 C7orf16
SRRT 7q22.1 / TRIP6 7q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRRT   24101
Cards
Entrez_Gene (NCBI)SRRT  51593  serrate, RNA effector molecule
AliasesARS2; ASR2; serrate
GeneCards (Weizmann)SRRT
Ensembl hg19 (Hinxton)ENSG00000087087 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087087 [Gene_View]  chr7:100875079-100888664 [Contig_View]  SRRT [Vega]
ICGC DataPortalENSG00000087087
TCGA cBioPortalSRRT
AceView (NCBI)SRRT
Genatlas (Paris)SRRT
WikiGenes51593
SOURCE (Princeton)SRRT
Genetics Home Reference (NIH)SRRT
Genomic and cartography
GoldenPath hg38 (UCSC)SRRT  -     chr7:100875079-100888664 +  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRRT  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblSRRT - 7q22.1 [CytoView hg19]  SRRT - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBISRRT [Mapview hg19]  SRRT [Mapview hg38]
OMIM614469   
Gene and transcription
Genbank (Entrez)AF082871 AF112994 AF248955 AK296131 AK302820
RefSeq transcript (Entrez)NM_001128852 NM_001128853 NM_001128854 NM_015908 NM_182800
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRRT
Cluster EST : UnigeneHs.111801 [ NCBI ]
CGAP (NCI)Hs.111801
Alternative Splicing GalleryENSG00000087087
Gene ExpressionSRRT [ NCBI-GEO ]   SRRT [ EBI - ARRAY_EXPRESS ]   SRRT [ SEEK ]   SRRT [ MEM ]
Gene Expression Viewer (FireBrowse)SRRT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51593
GTEX Portal (Tissue expression)SRRT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXP5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXP5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXP5
Splice isoforms : SwissVarQ9BXP5
PhosPhoSitePlusQ9BXP5
Domains : Interpro (EBI)Arsenite-R_2    DUF3546    RRM_dom   
Domain families : Pfam (Sanger)ARS2 (PF04959)    DUF3546 (PF12066)   
Domain families : Pfam (NCBI)pfam04959    pfam12066   
Conserved Domain (NCBI)SRRT
DMDM Disease mutations51593
Blocks (Seattle)SRRT
SuperfamilyQ9BXP5
Human Protein AtlasENSG00000087087
Peptide AtlasQ9BXP5
HPRD10665
IPIIPI00375144   IPI00220038   IPI00888510   IPI00888085   IPI00927582   IPI00414434   IPI01018901   IPI00925555   IPI00925539   IPI00924874   IPI00925189   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXP5
IntAct (EBI)Q9BXP5
FunCoupENSG00000087087
BioGRIDSRRT
STRING (EMBL)SRRT
ZODIACSRRT
Ontologies - Pathways
QuickGOQ9BXP5
Ontology : AmiGOmRNA splicing, via spliceosome  DNA binding  RNA binding  protein binding  nucleoplasm  nucleoplasm  nucleoplasm  cytoplasm  regulation of transcription, DNA-templated  cell proliferation  primary miRNA processing  snRNA transcription from RNA polymerase II promoter  protein complex  response to arsenic-containing substance  positive regulation of neurogenesis  neuronal stem cell population maintenance  
Ontology : EGO-EBImRNA splicing, via spliceosome  DNA binding  RNA binding  protein binding  nucleoplasm  nucleoplasm  nucleoplasm  cytoplasm  regulation of transcription, DNA-templated  cell proliferation  primary miRNA processing  snRNA transcription from RNA polymerase II promoter  protein complex  response to arsenic-containing substance  positive regulation of neurogenesis  neuronal stem cell population maintenance  
NDEx NetworkSRRT
Atlas of Cancer Signalling NetworkSRRT
Wikipedia pathwaysSRRT
Orthology - Evolution
OrthoDB51593
GeneTree (enSembl)ENSG00000087087
Phylogenetic Trees/Animal Genes : TreeFamSRRT
HOVERGENQ9BXP5
HOGENOMQ9BXP5
Homologs : HomoloGeneSRRT
Homology/Alignments : Family Browser (UCSC)SRRT
Gene fusions - Rearrangements
Fusion : MitelmanSRRT/PPP1R17 [7q22.1/7p14.3]  
Fusion : MitelmanSRRT/TRIP6 [7q22.1/7q22.1]  [t(7;7)(q22;q22)]  
Fusion: TCGASRRT 7q22.1 C7orf16 GBM
Fusion: TCGASRRT 7q22.1 TRIP6 7q22.1 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRRT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRRT
dbVarSRRT
ClinVarSRRT
1000_GenomesSRRT 
Exome Variant ServerSRRT
ExAC (Exome Aggregation Consortium)SRRT (select the gene name)
Genetic variants : HAPMAP51593
Genomic Variants (DGV)SRRT [DGVbeta]
DECIPHERSRRT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRRT 
Mutations
ICGC Data PortalSRRT 
TCGA Data PortalSRRT 
Broad Tumor PortalSRRT
OASIS PortalSRRT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRRT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRRT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRRT
DgiDB (Drug Gene Interaction Database)SRRT
DoCM (Curated mutations)SRRT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRRT (select a term)
intoGenSRRT
Cancer3DSRRT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614469   
Orphanet
MedgenSRRT
Genetic Testing Registry SRRT
NextProtQ9BXP5 [Medical]
TSGene51593
GENETestsSRRT
Target ValidationSRRT
Huge Navigator SRRT [HugePedia]
snp3D : Map Gene to Disease51593
BioCentury BCIQSRRT
ClinGenSRRT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51593
Chemical/Pharm GKB GenePA164726295
Clinical trialSRRT
Miscellaneous
canSAR (ICR)SRRT (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRRT
EVEXSRRT
GoPubMedSRRT
iHOPSRRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:57:27 CEST 2017

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