SRSF10 (serine and arginine rich splicing factor 10)

2003-02-01  

Identity

HGNC
LOCATION
1p36.11
LOCUSID
ALIAS
FUSIP1,FUSIP2,NSSR,PPP1R149,SFRS13,SFRS13A,SRp38,SRrp40,TASR,TASR1,TASR2
FUSION GENES

Other Information

Locus ID:

NCBI: 10772
MIM: 605221
HGNC: 16713
Ensembl: ENSG00000188529

Variants:

dbSNP: 10772
ClinVar: 10772
TCGA: ENSG00000188529
COSMIC: SRSF10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188529ENST00000343255O75494
ENSG00000188529ENST00000344989O75494
ENSG00000188529ENST00000374452O75494
ENSG00000188529ENST00000374453Q5JRI1
ENSG00000188529ENST00000453840O75494
ENSG00000188529ENST00000473858R4GMP8
ENSG00000188529ENST00000484146O75494
ENSG00000188529ENST00000492112O75494
ENSG00000188529ENST00000492112A0A0S2Z504
ENSG00000188529ENST00000495785Q6IQ42

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
268769372016Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.262
124192502002The SR protein SRp38 represses splicing in M phase cells.80
147651982004Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock.71
250910512014BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.39
278519632016SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors.16
202324162010Role of SFRS13A in low-density lipoprotein receptor splicing.13
161358202005Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins.9
293964852018hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.6
211351272011Heat shock-induced SRSF10 dephosphorylation displays thermotolerance mediated by Hsp27.5
219841582011[Expression of neural salient serine-/arginine-rich protein 1 (NSSR1) in colorectal cancer].1

Citation

Dessen P

SRSF10 (serine and arginine rich splicing factor 10)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40648/srsf10