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SRSF10 (serine and arginine rich splicing factor 10)

Identity

Alias_namesFUSIP2
FUSIP1
SFRS13A
FUS-interacting protein (serine-arginine rich) 2
FUS interacting protein (serine/arginine-rich) 1
splicing factor, arginine/serine-rich 13A
neural-salient SR protein
serine/arginine-rich splicing factor 10
Alias_symbol (synonym)TASR1
TASR2
SRp38
SRrp40
SFRS13
PPP1R149
Other aliasNSSR
TASR
HGNC (Hugo) SRSF10
LocusID (NCBI) 10772
Atlas_Id 40648
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 23964347 and ends at 23980463 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SRSF10 (1p36.11) / SFTPB (2p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRSF10   16713
Cards
Entrez_Gene (NCBI)SRSF10  10772  serine and arginine rich splicing factor 10
AliasesFUSIP1; FUSIP2; NSSR; PPP1R149; 
SFRS13; SFRS13A; SRp38; SRrp40; TASR; TASR1; TASR2
GeneCards (Weizmann)SRSF10
Ensembl hg19 (Hinxton)ENSG00000188529 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188529 [Gene_View]  chr1:23964347-23980463 [Contig_View]  SRSF10 [Vega]
ICGC DataPortalENSG00000188529
TCGA cBioPortalSRSF10
AceView (NCBI)SRSF10
Genatlas (Paris)SRSF10
WikiGenes10772
SOURCE (Princeton)SRSF10
Genetics Home Reference (NIH)SRSF10
Genomic and cartography
GoldenPath hg38 (UCSC)SRSF10  -     chr1:23964347-23980463 -  1p36.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRSF10  -     1p36.11   [Description]    (hg19-Feb_2009)
EnsemblSRSF10 - 1p36.11 [CytoView hg19]  SRSF10 - 1p36.11 [CytoView hg38]
Mapping of homologs : NCBISRSF10 [Mapview hg19]  SRSF10 [Mapview hg38]
OMIM605221   
Gene and transcription
Genbank (Entrez)AA808243 AF047448 AF067730 AF419331 AF449427
RefSeq transcript (Entrez)NM_001191005 NM_001191006 NM_001191007 NM_001191009 NM_001300936 NM_001300937 NM_006625 NM_054016
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRSF10
Cluster EST : UnigeneHs.3530 [ NCBI ]
CGAP (NCI)Hs.3530
Alternative Splicing GalleryENSG00000188529
Gene ExpressionSRSF10 [ NCBI-GEO ]   SRSF10 [ EBI - ARRAY_EXPRESS ]   SRSF10 [ SEEK ]   SRSF10 [ MEM ]
Gene Expression Viewer (FireBrowse)SRSF10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10772
GTEX Portal (Tissue expression)SRSF10
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75494   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75494  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75494
Splice isoforms : SwissVarO75494
PhosPhoSitePlusO75494
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)SRSF10
DMDM Disease mutations10772
Blocks (Seattle)SRSF10
SuperfamilyO75494
Human Protein AtlasENSG00000188529
Peptide AtlasO75494
HPRD05562
IPIIPI00074587   IPI00009071   IPI00386662   IPI00979506   
Protein Interaction databases
DIP (DOE-UCLA)O75494
IntAct (EBI)O75494
FunCoupENSG00000188529
BioGRIDSRSF10
STRING (EMBL)SRSF10
ZODIACSRSF10
Ontologies - Pathways
QuickGOO75494
Ontology : AmiGOspliceosomal tri-snRNP complex assembly  RNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  RNA binding  RNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  regulation of transcription, DNA-templated  mRNA splice site selection  mRNA export from nucleus  cytosolic transport  nuclear speck  regulation of mRNA splicing, via spliceosome  negative regulation of mRNA splicing, via spliceosome  RS domain binding  unfolded protein binding  
Ontology : EGO-EBIspliceosomal tri-snRNP complex assembly  RNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  RNA binding  RNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  regulation of transcription, DNA-templated  mRNA splice site selection  mRNA export from nucleus  cytosolic transport  nuclear speck  regulation of mRNA splicing, via spliceosome  negative regulation of mRNA splicing, via spliceosome  RS domain binding  unfolded protein binding  
Pathways : KEGGSpliceosome   
NDEx NetworkSRSF10
Atlas of Cancer Signalling NetworkSRSF10
Wikipedia pathwaysSRSF10
Orthology - Evolution
OrthoDB10772
GeneTree (enSembl)ENSG00000188529
Phylogenetic Trees/Animal Genes : TreeFamSRSF10
HOVERGENO75494
HOGENOMO75494
Homologs : HomoloGeneSRSF10
Homology/Alignments : Family Browser (UCSC)SRSF10
Gene fusions - Rearrangements
Fusion Cancer (Beijing)SRSF10 [1p36.11]  -  SFTPB [2p11.2]  [FUSC003117]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRSF10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRSF10
dbVarSRSF10
ClinVarSRSF10
1000_GenomesSRSF10 
Exome Variant ServerSRSF10
ExAC (Exome Aggregation Consortium)SRSF10 (select the gene name)
Genetic variants : HAPMAP10772
Genomic Variants (DGV)SRSF10 [DGVbeta]
DECIPHERSRSF10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRSF10 
Mutations
ICGC Data PortalSRSF10 
TCGA Data PortalSRSF10 
Broad Tumor PortalSRSF10
OASIS PortalSRSF10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRSF10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRSF10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRSF10
DgiDB (Drug Gene Interaction Database)SRSF10
DoCM (Curated mutations)SRSF10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRSF10 (select a term)
intoGenSRSF10
Cancer3DSRSF10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605221   
Orphanet
MedgenSRSF10
Genetic Testing Registry SRSF10
NextProtO75494 [Medical]
TSGene10772
GENETestsSRSF10
Target ValidationSRSF10
Huge Navigator SRSF10 [HugePedia]
snp3D : Map Gene to Disease10772
BioCentury BCIQSRSF10
ClinGenSRSF10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10772
Chemical/Pharm GKB GenePA28427
Clinical trialSRSF10
Miscellaneous
canSAR (ICR)SRSF10 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRSF10
EVEXSRSF10
GoPubMedSRSF10
iHOPSRSF10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:03 CEST 2017

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