Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SRSF11 (serine and arginine rich splicing factor 11)

Identity

Alias_namesSFRS11
splicing factor, arginine/serine-rich 11
serine/arginine-rich splicing factor 11
Alias_symbol (synonym)p54
NET2
Other aliasdJ677H15.2
HGNC (Hugo) SRSF11
LocusID (NCBI) 9295
Atlas_Id 74249
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 70205682 and ends at 70252018 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C9orf78 (9q34.11) / SRSF11 (1p31.1)DDX6 (11q23.3) / SRSF11 (1p31.1)NEGR1 (1p31.1) / SRSF11 (1p31.1)
QRICH1 (3p21.31) / SRSF11 (1p31.1)SRSF11 (1p31.1) / AFF1 (4q21.3)SRSF11 (1p31.1) / ARHGAP11A (15q13.3)
SRSF11 (1p31.1) / CAMTA1 (1p36.31)SRSF11 (1p31.1) / FUS (16p11.2)SRSF11 (1p31.1) / SRSF11 (1p31.1)
SRSF11 (1p31.1) / TXNRD1 (12q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SRSF11   10782
Cards
Entrez_Gene (NCBI)SRSF11  9295  serine and arginine rich splicing factor 11
AliasesNET2; SFRS11; dJ677H15.2; p54
GeneCards (Weizmann)SRSF11
Ensembl hg19 (Hinxton)ENSG00000116754 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116754 [Gene_View]  chr1:70205682-70252018 [Contig_View]  SRSF11 [Vega]
ICGC DataPortalENSG00000116754
TCGA cBioPortalSRSF11
AceView (NCBI)SRSF11
Genatlas (Paris)SRSF11
WikiGenes9295
SOURCE (Princeton)SRSF11
Genetics Home Reference (NIH)SRSF11
Genomic and cartography
GoldenPath hg38 (UCSC)SRSF11  -     chr1:70205682-70252018 +  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRSF11  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblSRSF11 - 1p31.1 [CytoView hg19]  SRSF11 - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBISRSF11 [Mapview hg19]  SRSF11 [Mapview hg38]
OMIM602010   
Gene and transcription
Genbank (Entrez)AB062486 AF086515 AI002238 AK021742 AK300147
RefSeq transcript (Entrez)NM_001190987 NM_001350605 NM_001350606 NM_001350607 NM_001350608 NM_001350609 NM_001350610 NM_001350611 NM_001350612 NM_001350613 NM_001350614 NM_001350615 NM_001350616 NM_004768
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SRSF11
Cluster EST : UnigeneHs.479693 [ NCBI ]
CGAP (NCI)Hs.479693
Alternative Splicing GalleryENSG00000116754
Gene ExpressionSRSF11 [ NCBI-GEO ]   SRSF11 [ EBI - ARRAY_EXPRESS ]   SRSF11 [ SEEK ]   SRSF11 [ MEM ]
Gene Expression Viewer (FireBrowse)SRSF11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9295
GTEX Portal (Tissue expression)SRSF11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05519   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ05519  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ05519
Splice isoforms : SwissVarQ05519
PhosPhoSitePlusQ05519
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)SRSF11
DMDM Disease mutations9295
Blocks (Seattle)SRSF11
SuperfamilyQ05519
Human Protein AtlasENSG00000116754
Peptide AtlasQ05519
HPRD03599
IPIIPI00464952   IPI00910208   IPI00908907   IPI00815763   IPI00641287   IPI00641957   IPI00641842   
Protein Interaction databases
DIP (DOE-UCLA)Q05519
IntAct (EBI)Q05519
FunCoupENSG00000116754
BioGRIDSRSF11
STRING (EMBL)SRSF11
ZODIACSRSF11
Ontologies - Pathways
QuickGOQ05519
Ontology : AmiGOmRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  termination of RNA polymerase II transcription  mRNA processing  RNA export from nucleus  mRNA export from nucleus  RNA splicing  nuclear speck  mRNA 3'-end processing  
Ontology : EGO-EBImRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  termination of RNA polymerase II transcription  mRNA processing  RNA export from nucleus  mRNA export from nucleus  RNA splicing  nuclear speck  mRNA 3'-end processing  
NDEx NetworkSRSF11
Atlas of Cancer Signalling NetworkSRSF11
Wikipedia pathwaysSRSF11
Orthology - Evolution
OrthoDB9295
GeneTree (enSembl)ENSG00000116754
Phylogenetic Trees/Animal Genes : TreeFamSRSF11
HOVERGENQ05519
HOGENOMQ05519
Homologs : HomoloGeneSRSF11
Homology/Alignments : Family Browser (UCSC)SRSF11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRSF11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRSF11
dbVarSRSF11
ClinVarSRSF11
1000_GenomesSRSF11 
Exome Variant ServerSRSF11
ExAC (Exome Aggregation Consortium)SRSF11 (select the gene name)
Genetic variants : HAPMAP9295
Genomic Variants (DGV)SRSF11 [DGVbeta]
DECIPHERSRSF11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRSF11 
Mutations
ICGC Data PortalSRSF11 
TCGA Data PortalSRSF11 
Broad Tumor PortalSRSF11
OASIS PortalSRSF11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRSF11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSRSF11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SRSF11
DgiDB (Drug Gene Interaction Database)SRSF11
DoCM (Curated mutations)SRSF11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SRSF11 (select a term)
intoGenSRSF11
Cancer3DSRSF11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602010   
Orphanet
MedgenSRSF11
Genetic Testing Registry SRSF11
NextProtQ05519 [Medical]
TSGene9295
GENETestsSRSF11
Target ValidationSRSF11
Huge Navigator SRSF11 [HugePedia]
snp3D : Map Gene to Disease9295
BioCentury BCIQSRSF11
ClinGenSRSF11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9295
Chemical/Pharm GKB GenePA35698
Clinical trialSRSF11
Miscellaneous
canSAR (ICR)SRSF11 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSRSF11
EVEXSRSF11
GoPubMedSRSF11
iHOPSRSF11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:40:30 CEST 2017

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