Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SRSF8 (serine and arginine rich splicing factor 8)

Identity

Alias (NCBI)DSM-1
SFRS2B
SRP46
HGNC (Hugo) SRSF8
HGNC Alias symbSRP46
HGNC Alias nameSR splicing factor 8
HGNC Previous nameSFRS2B
HGNC Previous namesplicing factor, arginine/serine-rich 2B
 serine/arginine-rich splicing factor 8
LocusID (NCBI) 10929
Atlas_Id 74252
Location 11q21  [Link to chromosome band 11q21]
Location_base_pair Starts at 95066877 and ends at 95071224 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SRSF8   16988
Cards
Entrez_Gene (NCBI)SRSF8    serine and arginine rich splicing factor 8
AliasesDSM-1; SFRS2B; SRP46
GeneCards (Weizmann)SRSF8
Ensembl hg19 (Hinxton)ENSG00000263465 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000263465 [Gene_View]  ENSG00000263465 [Sequence]  chr11:95066877-95071224 [Contig_View]  SRSF8 [Vega]
ICGC DataPortalENSG00000263465
TCGA cBioPortalSRSF8
AceView (NCBI)SRSF8
Genatlas (Paris)SRSF8
SOURCE (Princeton)SRSF8
Genetics Home Reference (NIH)SRSF8
Genomic and cartography
GoldenPath hg38 (UCSC)SRSF8  -     chr11:95066877-95071224 +  11q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SRSF8  -     11q21   [Description]    (hg19-Feb_2009)
GoldenPathSRSF8 - 11q21 [CytoView hg19]  SRSF8 - 11q21 [CytoView hg38]
ImmunoBaseENSG00000263465
Genome Data Viewer NCBISRSF8 [Mapview hg19]  
OMIM603269   
Gene and transcription
Genbank (Entrez)AF031166 AJ270685 AK023379 AK309776 AK312514
RefSeq transcript (Entrez)NM_032102
Consensus coding sequences : CCDS (NCBI)SRSF8
Gene ExpressionSRSF8 [ NCBI-GEO ]   SRSF8 [ EBI - ARRAY_EXPRESS ]   SRSF8 [ SEEK ]   SRSF8 [ MEM ]
Gene Expression Viewer (FireBrowse)SRSF8 [ Firebrowse - Broad ]
GenevisibleExpression of SRSF8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10929
GTEX Portal (Tissue expression)SRSF8
Human Protein AtlasENSG00000263465-SRSF8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRL6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRL6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRL6
PhosPhoSitePlusQ9BRL6
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait_sf    RBD_domain_sf    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)SRSF8
PDB (RSDB)2DNM   
PDB Europe2DNM   
PDB (PDBSum)2DNM   
PDB (IMB)2DNM   
Structural Biology KnowledgeBase2DNM   
SCOP (Structural Classification of Proteins)2DNM   
CATH (Classification of proteins structures)2DNM   
SuperfamilyQ9BRL6
AlphaFold pdb e-kbQ9BRL6   
Human Protein Atlas [tissue]ENSG00000263465-SRSF8 [tissue]
HPRD04466
Protein Interaction databases
DIP (DOE-UCLA)Q9BRL6
IntAct (EBI)Q9BRL6
BioGRIDSRSF8
STRING (EMBL)SRSF8
ZODIACSRSF8
Ontologies - Pathways
QuickGOQ9BRL6
Ontology : AmiGOmRNA splicing, via spliceosome  RNA binding  RNA binding  protein binding  nucleoplasm  cytoplasm  cytosol  nuclear speck  nuclear speck  
Ontology : EGO-EBImRNA splicing, via spliceosome  RNA binding  RNA binding  protein binding  nucleoplasm  cytoplasm  cytosol  nuclear speck  nuclear speck  
NDEx NetworkSRSF8
Atlas of Cancer Signalling NetworkSRSF8
Wikipedia pathwaysSRSF8
Orthology - Evolution
OrthoDB10929
GeneTree (enSembl)ENSG00000263465
Phylogenetic Trees/Animal Genes : TreeFamSRSF8
Homologs : HomoloGeneSRSF8
Homology/Alignments : Family Browser (UCSC)SRSF8
Gene fusions - Rearrangements
Fusion : QuiverSRSF8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSRSF8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRSF8
dbVarSRSF8
ClinVarSRSF8
MonarchSRSF8
1000_GenomesSRSF8 
Exome Variant ServerSRSF8
GNOMAD BrowserENSG00000263465
Varsome BrowserSRSF8
ACMGSRSF8 variants
VarityQ9BRL6
Genomic Variants (DGV)SRSF8 [DGVbeta]
DECIPHERSRSF8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSRSF8 
Mutations
ICGC Data PortalSRSF8 
TCGA Data PortalSRSF8 
Broad Tumor PortalSRSF8
OASIS PortalSRSF8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSRSF8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSRSF8
Mutations and Diseases : HGMDSRSF8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSRSF8
DgiDB (Drug Gene Interaction Database)SRSF8
DoCM (Curated mutations)SRSF8
CIViC (Clinical Interpretations of Variants in Cancer)SRSF8
Cancer3DSRSF8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603269   
Orphanet
DisGeNETSRSF8
MedgenSRSF8
Genetic Testing Registry SRSF8
NextProtQ9BRL6 [Medical]
GENETestsSRSF8
Target ValidationSRSF8
Huge Navigator SRSF8 [HugePedia]
ClinGenSRSF8
Clinical trials, drugs, therapy
MyCancerGenomeSRSF8
Protein Interactions : CTDSRSF8
Pharm GKB GenePA165543687
PharosQ9BRL6
Clinical trialSRSF8
Miscellaneous
canSAR (ICR)SRSF8
HarmonizomeSRSF8
DataMed IndexSRSF8
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSRSF8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:24:13 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.