SRSF9 (serine and arginine rich splicing factor 9)

2012-03-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
SFRS9,SRp30c
FUSION GENES

Other Information

Locus ID:

NCBI: 8683
MIM: 601943
HGNC: 10791
Ensembl: ENSG00000111786

Variants:

dbSNP: 8683
ClinVar: 8683
TCGA: ENSG00000111786
COSMIC: SRSF9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111786ENST00000229390Q13242
ENSG00000111786ENST00000550458H0YIB4
ENSG00000111786ENST00000603963S4R3G0

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Herpes simplex infectionKEGGko05168
Herpes simplex infectionKEGGhsa05168
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
355091012022SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner.9
359711212022High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.2
363307102022Investigation of the effect of SRSF9 overexpression on HIV-1 production.1
355091012022SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner.9
359711212022High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.2
363307102022Investigation of the effect of SRSF9 overexpression on HIV-1 production.1
332486882021AMP-activated protein kinase regulates β-catenin protein synthesis by phosphorylating serine/arginine-rich splicing factor 9.2
338086562021SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon.5
332486882021AMP-activated protein kinase regulates β-catenin protein synthesis by phosphorylating serine/arginine-rich splicing factor 9.2
338086562021SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon.5
317825502020LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation.60
317825502020LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation.60
305657442019microRNA-802 inhibits cell proliferation and induces apoptosis in human cervical cancer by targeting serine/arginine-rich splicing factor 9.22
305657442019microRNA-802 inhibits cell proliferation and induces apoptosis in human cervical cancer by targeting serine/arginine-rich splicing factor 9.22
299922932018SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates.16

Citation

Dessen P

SRSF9 (serine and arginine rich splicing factor 9)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52656/srsf9