Atlas of Genetics and Cytogenetics in Oncology and Haematology


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X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SRY (sex determining region Y)

Identity

Other namesSRXX1
SRXY1
TDF
TDY
HGNC (Hugo) SRY
LocusID (NCBI) 6736
Location Yp11.31
Location_base_pair Starts at 2654896 and ends at 2655782 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SRY   11311
Cards
Entrez_Gene (NCBI)SRY  6736  sex determining region Y
GeneCards (Weizmann)SRY
Ensembl (Hinxton) [Gene_View]  chrY:2654896-2655782 [Contig_View]  SRY [Vega]
AceView (NCBI)SRY
Genatlas (Paris)SRY
WikiGenes6736
SOURCE (Princeton)NM_003140
Genomic and cartography
GoldenPath (UCSC)SRY  -  Yp11.31   chrY:2654896-2655782 -  Yp11.31   [Description]    (hg19-Feb_2009)
EnsemblSRY - Yp11.31 [CytoView]
Mapping of homologs : NCBISRY [Mapview]
OMIM400044   400045   480000   
Gene and transcription
Genbank (Entrez)BC074923 BC074924 EU446863 L10101 S53156
RefSeq transcript (Entrez)NM_003140
RefSeq genomic (Entrez)AC_000156 NC_000024 NG_011751 NT_011896 NW_001842422
Consensus coding sequences : CCDS (NCBI)SRY
Cluster EST : UnigeneHs.1992 [ NCBI ]
CGAP (NCI)Hs.1992
Alternative Splicing : Fast-db (Paris)GSHG0033761
Gene ExpressionSRY [ NCBI-GEO ]     SRY [ SEEK ]   SRY [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05066 (Uniprot)
NextProtQ05066  [Medical]
With graphics : InterProQ05066
Splice isoforms : SwissVarQ05066 (Swissvar)
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom    TF_Sry   
Related proteins : CluSTrQ05066
Domain families : Pfam (Sanger)HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam00505   
Domain families : Smart (EMBL)HMG (SM00398)  
DMDM Disease mutations6736
Blocks (Seattle)Q05066
PDB (SRS)1HRY    1HRZ    1J46    1J47    2GZK   
PDB (PDBSum)1HRY    1HRZ    1J46    1J47    2GZK   
PDB (IMB)1HRY    1HRZ    1J46    1J47    2GZK   
PDB (RSDB)1HRY    1HRZ    1J46    1J47    2GZK   
Peptide AtlasQ05066
HPRD08364
IPIIPI00011568   IPI00956692   IPI01013243   IPI01012788   IPI00385239   IPI00385240   
Protein Interaction databases
DIP (DOE-UCLA)Q05066
IntAct (EBI)Q05066
BioGRIDSRY
InParanoidQ05066
Interologous Interaction database Q05066
IntegromeDBSRY
STRING (EMBL)SRY
Ontologies - Pathways
Ontology : AmiGODNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity  calmodulin binding  nucleus  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  sex differentiation  transcription factor binding  nuclear speck  cell differentiation  male sex determination  positive regulation of transcription, DNA-templated  positive regulation of male gonad development  
Ontology : EGO-EBIDNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity  calmodulin binding  nucleus  nucleus  cytoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  sex differentiation  transcription factor binding  nuclear speck  cell differentiation  male sex determination  positive regulation of transcription, DNA-templated  positive regulation of male gonad development  
Protein Interaction DatabaseSRY
Wikipedia pathwaysSRY
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SRY
SNP (GeneSNP Utah)SRY
SNP : HGBaseSRY
Genetic variants : HAPMAPSRY
1000_GenomesSRY 
CONAN: Copy Number AnalysisSRY 
Somatic Mutations in Cancer : COSMICSRY 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDSRY
OMIM400044    400045    480000   
MedgenSRY
GENETestsSRY
Disease Genetic AssociationSRY
Huge Navigator SRY [HugePedia]  SRY [HugeCancerGEM]
Genomic VariantsSRY  SRY [DGVbeta]
Exome VariantSRY
dbVarSRY
ClinVarSRY
snp3D : Map Gene to Disease6736
General knowledge
Homologs : HomoloGeneSRY
Homology/Alignments : Family Browser (UCSC)SRY
Phylogenetic Trees/Animal Genes : TreeFamSRY
Chemical/Protein Interactions : CTD6736
Chemical/Pharm GKB GenePA36135
Clinical trialSRY
Other databases
Probes
Litterature
PubMed156 Pubmed reference(s) in Entrez
CoreMineSRY
iHOPSRY
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:19:00 CEST 2014

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