Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SRY (sex determining region Y)

Identity

Other namesTDF
TDY
HGNC (Hugo) SRY
Location Yp11.31
Location_base_pair Starts at 2714896 and ends at 2715792 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SRY   11311
Entrez_Gene (NCBI)SRY  6736  sex determining region Y
Cards
GeneCards (Weizmann)SRY
Ensembl (Hinxton)ENSG00000184895 [Gene_View]  SRY [Vega]
AceView (NCBI)SRY
Genatlas (Paris)SRY
euGene (Indiana)6736
SOURCE (Stanford)NM_003140
Gene Expression (Array Express) ENSG00000184895
Genomic and cartography
GoldenPath (UCSC)SRY  -  Yp11.31   chrY:2714896-2715792 -  Yp11.31   [Description]    (hg18-March_2006)
EnsemblSRY - Yp11.31 [CytoView]
Mapping of homologs : NCBISRY [Mapview]
OMIM235600   306100   400044   400045   480000   
Gene and transcription
Gene : Genbank (Entrez)BC074923 BC074924 EU446863 L10101 S53156
Reference sequence (RefSeq transcript) :SRSNM_003140
Reference transcript : EntrezNM_003140
RefSeq genomic : SRSAC_000066 AC_000156 NC_000024 NG_011751 NT_011896 NW_001842422 NW_927715
RefSeq genomic : EntrezAC_000066 AC_000156 NC_000024 NG_011751 NT_011896 NW_001842422 NW_927715
Consensus coding sequences : CCDS NCBISRY
Cluster EST : UnigeneHs.1992 [ SRS ] Hs.1992 [ NCBI ]
Alternative Splicing : Fast-db (Paris)711
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ05066 (SRS) Q05066 (Expasy) Q05066 (Uniprot)
With graphics : InterProQ05066
Splice isoforms : VarSplice FASTAQ05066(VarSplice FASTA)
Domaine pattern : Prosite (SRS)HMG_BOX_2 (PS50118)   
Domain pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (SRS)HMG_HMG1/HMG2    HMG_superfamily    Sex-determining_region_Y   
Domains : Interpro (EBI)HMG_HMG1/HMG2    HMG_superfamily    Sex-determining_region_Y   
Related proteins : CluSTrQ05066
Domain families : Pfam SRSHMG_box (PF00505)   
Domain families : Pfam SangerHMG_box (PF00505)   
Domain families : Pfam NCBIpfam00505   
Domain families : Smart EMBLHMG (SM00398)  
Blocks (Seattle)Q05066
Crystal structure of protein : PDB SRS1HRY    1HRZ    1J46    1J47   
Crystal structure of protein : PDBSum1HRY    1HRZ    1J46    1J47   
Crystal structure of protein : IMB1HRY    1HRZ    1J46    1J47   
Crystal structure of protein : PDB RSDB1HRY    1HRZ    1J46    1J47   
HPRD08364
Protein Interaction databases
DIP (DOE-UCLA)Q05066
IntAct (EBI)Q05066
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBISRY
SNP : GeneSNP UtahSRY
SNP : HGBaseSRY
Genetic variants : HAPMAPSRY
Mutations and Diseases : HGMDSRY
Hereditary diseases : OMIM235600    306100    400044    400045    480000   
Hereditary diseases : GENETests235600    306100    400044    400045    480000   
Diseases : Genetic AssociationSRY
General knowledge
Homologs : HomoloGeneSRY
Homology/Alignments : Family Browser UCSCSRY
Phylogenetic Trees/Animal Genes : TreeFamSRY
Chemical/Protein Interactions : CTD6736
Keywords Ontology : AmiGOtranscription factor activity  protein binding  nucleus  cytoplasm  sex differentiation  transcription activator activity  nuclear speck  cell differentiation  male sex determination  regulation of transcription  
Keywords Ontology : EGO-EBItranscription factor activity  protein binding  nucleus  cytoplasm  sex differentiation  transcription activator activity  nuclear speck  cell differentiation  male sex determination  regulation of transcription  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesSRY Related clones (RZPD - Berlin)
Literature
PubMed109 Pubmed reference(s) in Entrez
PubGeneSRY
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:45:55 CET 2010
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