SSBP2 (single stranded DNA binding protein 2)

2007-02-01  

Identity

HGNC
LOCATION
5q14.1
LOCUSID
ALIAS
HSPC116,SOSS-B2
FUSION GENES

Other Information

Locus ID:

NCBI: 23635
MIM: 607389
HGNC: 15831
Ensembl: ENSG00000145687

Variants:

dbSNP: 23635
ClinVar: 23635
TCGA: ENSG00000145687
COSMIC: SSBP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145687ENST00000320672P81877
ENSG00000145687ENST00000504985H0Y9V4
ENSG00000145687ENST00000505980P81877
ENSG00000145687ENST00000509013D6RAC5
ENSG00000145687ENST00000509053P81877
ENSG00000145687ENST00000512923H0Y9M5
ENSG00000145687ENST00000514493P81877
ENSG00000145687ENST00000515395P81877
ENSG00000145687ENST00000615665A0A087X159

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
157821452005SSBP2, a candidate tumor suppressor gene, induces growth arrest and differentiation of myeloid leukemia cells.25
120792862002A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity.19
186187142008Novel SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia.18
185595932008ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.16
206585322011Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma.16
173110032007Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes.14
224721742012SSBP2 variants are associated with survival in glioblastoma patients.11
196581002009Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.4
306766652019Crystal structure of the LUFS domain of human single-stranded DNA binding Protein 2 (SSBP2).3

Citation

Dessen P

SSBP2 (single stranded DNA binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46000/ssbp2