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SSH1 (slingshot protein phosphatase 1)

Identity

Other namesSSH1L
HGNC (Hugo) SSH1
LocusID (NCBI) 54434
Location 12q24.11
Location_base_pair Starts at 109185695 and ends at 109251359 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SSH1   30579
Cards
Entrez_Gene (NCBI)SSH1  54434  slingshot protein phosphatase 1
GeneCards (Weizmann)SSH1
Ensembl (Hinxton)ENSG00000084112 [Gene_View]  chr12:109185695-109251359 [Contig_View]  SSH1 [Vega]
ICGC DataPortalENSG00000084112
AceView (NCBI)SSH1
Genatlas (Paris)SSH1
WikiGenes54434
SOURCE (Princeton)NM_001161330 NM_001161331 NM_018984
Genomic and cartography
GoldenPath (UCSC)SSH1  -  12q24.11   chr12:109185695-109251359 -  12q24.11   [Description]    (hg19-Feb_2009)
EnsemblSSH1 - 12q24.11 [CytoView]
Mapping of homologs : NCBISSH1 [Mapview]
OMIM606778   
Gene and transcription
Genbank (Entrez)AB037719 AB072355 AB072356 AB072357 AI621348
RefSeq transcript (Entrez)NM_001161330 NM_001161331 NM_018984
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_029846 NT_029419 NW_001838061 NW_004929384
Consensus coding sequences : CCDS (NCBI)SSH1
Cluster EST : UnigeneHs.199763 [ NCBI ]
CGAP (NCI)Hs.199763
Alternative Splicing : Fast-db (Paris)GSHG0007758
Alternative Splicing GalleryENSG00000084112
Gene ExpressionSSH1 [ NCBI-GEO ]     SSH1 [ SEEK ]   SSH1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WYL5 (Uniprot)
NextProtQ8WYL5  [Medical]
With graphics : InterProQ8WYL5
Splice isoforms : SwissVarQ8WYL5 (Swissvar)
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)DEK_C    Dual-sp_phosphatase_cat-dom    Dual-sp_phosphatase_subgr_cat    DUSP    Homeodomain-like    Prot-tyrosine_phosphatase-like    SSH1    Tyr/Dual-sp_Pase    Tyr_Pase_AS   
Related proteins : CluSTrQ8WYL5
Domain families : Pfam (Sanger)DEK_C (PF08766)    DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam08766    pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
DMDM Disease mutations54434
Blocks (Seattle)Q8WYL5
Human Protein AtlasENSG00000084112
Peptide AtlasQ8WYL5
HPRD09486
IPIIPI00103742   IPI00383250   IPI00103741   IPI00478191   IPI00167670   IPI01026587   IPI01022541   IPI01021141   IPI01022438   
Protein Interaction databases
DIP (DOE-UCLA)Q8WYL5
IntAct (EBI)Q8WYL5
FunCoupENSG00000084112
BioGRIDSSH1
IntegromeDBSSH1
STRING (EMBL)SSH1
Ontologies - Pathways
QuickGOQ8WYL5
Ontology : AmiGOcell morphogenesis  DNA binding  actin binding  phosphoprotein phosphatase activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  nucleolus  cytoplasm  cytoskeleton  plasma membrane  protein dephosphorylation  regulation of actin polymerization or depolymerization  protein tyrosine/serine/threonine phosphatase activity  regulation of lamellipodium assembly  lamellipodium  actin cytoskeleton organization  midbody  cleavage furrow  regulation of cellular protein metabolic process  peptidyl-tyrosine dephosphorylation  regulation of axonogenesis  cellular response to ATP  
Ontology : EGO-EBIcell morphogenesis  DNA binding  actin binding  phosphoprotein phosphatase activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  nucleolus  cytoplasm  cytoskeleton  plasma membrane  protein dephosphorylation  regulation of actin polymerization or depolymerization  protein tyrosine/serine/threonine phosphatase activity  regulation of lamellipodium assembly  lamellipodium  actin cytoskeleton organization  midbody  cleavage furrow  regulation of cellular protein metabolic process  peptidyl-tyrosine dephosphorylation  regulation of axonogenesis  cellular response to ATP  
Pathways : KEGGRegulation of actin cytoskeleton   
Protein Interaction DatabaseSSH1
Wikipedia pathwaysSSH1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SSH1
SNP (GeneSNP Utah)SSH1
SNP : HGBaseSSH1
Genetic variants : HAPMAPSSH1
1000_GenomesSSH1 
ICGC programENSG00000084112 
CONAN: Copy Number AnalysisSSH1 
Somatic Mutations in Cancer : COSMICSSH1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)12:109185695-109251359
Mutations and Diseases : HGMDSSH1
OMIM606778   
MedgenSSH1
GENETestsSSH1
Disease Genetic AssociationSSH1
Huge Navigator SSH1 [HugePedia]  SSH1 [HugeCancerGEM]
Genomic VariantsSSH1  SSH1 [DGVbeta]
Exome VariantSSH1
dbVarSSH1
ClinVarSSH1
snp3D : Map Gene to Disease54434
General knowledge
Homologs : HomoloGeneSSH1
Homology/Alignments : Family Browser (UCSC)SSH1
Phylogenetic Trees/Animal Genes : TreeFamSSH1
Chemical/Protein Interactions : CTD54434
Chemical/Pharm GKB GenePA134941788
Clinical trialSSH1
Cancer Resource (Charite)ENSG00000084112
Other databases
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
CoreMineSSH1
GoPubMedSSH1
iHOPSSH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:59:11 CET 2014

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