Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SSH1 (slingshot protein phosphatase 1)

Identity

Other namesSSH1L
HGNC (Hugo) SSH1
LocusID (NCBI) 54434
Atlas_Id 43787
Location 12q24.11  [Link to chromosome band 12q24]
Location_base_pair Starts at 109185695 and ends at 109251359 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SSH1 (12q24.11) / C1orf50 (1p34.2)SSH1 (12q24.11) / SSH1 (12q24.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SSH1   30579
Cards
Entrez_Gene (NCBI)SSH1  54434  slingshot protein phosphatase 1
AliasesSSH1L
GeneCards (Weizmann)SSH1
Ensembl hg19 (Hinxton)ENSG00000084112 [Gene_View]  chr12:109185695-109251359 [Contig_View]  SSH1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000084112 [Gene_View]  chr12:109185695-109251359 [Contig_View]  SSH1 [Vega]
ICGC DataPortalENSG00000084112
TCGA cBioPortalSSH1
AceView (NCBI)SSH1
Genatlas (Paris)SSH1
WikiGenes54434
SOURCE (Princeton)SSH1
Genomic and cartography
GoldenPath hg19 (UCSC)SSH1  -     chr12:109185695-109251359 -  12q24.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SSH1  -     12q24.11   [Description]    (hg38-Dec_2013)
EnsemblSSH1 - 12q24.11 [CytoView hg19]  SSH1 - 12q24.11 [CytoView hg38]
Mapping of homologs : NCBISSH1 [Mapview hg19]  SSH1 [Mapview hg38]
OMIM606778   
Gene and transcription
Genbank (Entrez)AB037719 AB072355 AB072356 AB072357 AI621348
RefSeq transcript (Entrez)NM_001161330 NM_001161331 NM_018984
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_029846 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)SSH1
Cluster EST : UnigeneHs.199763 [ NCBI ]
CGAP (NCI)Hs.199763
Alternative Splicing GalleryENSG00000084112
Gene ExpressionSSH1 [ NCBI-GEO ]   SSH1 [ EBI - ARRAY_EXPRESS ]   SSH1 [ SEEK ]   SSH1 [ MEM ]
Gene Expression Viewer (FireBrowse)SSH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54434
GTEX Portal (Tissue expression)SSH1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WYL5 (Uniprot)
NextProtQ8WYL5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WYL5
Splice isoforms : SwissVarQ8WYL5 (Swissvar)
Catalytic activity : Enzyme3.1.3.16 [ Enzyme-Expasy ]   3.1.3.163.1.3.16 [ IntEnz-EBI ]   3.1.3.16 [ BRENDA ]   3.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ8WYL5
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)DEK_C    Dual-sp_phosphatase_cat-dom    DUSP    Homeodomain-like    Prot-tyrosine_phosphatase-like    SSH1    Tyr_Pase_AS    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DEK_C (PF08766)    DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam08766    pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
DMDM Disease mutations54434
Blocks (Seattle)SSH1
SuperfamilyQ8WYL5
Human Protein AtlasENSG00000084112
Peptide AtlasQ8WYL5
HPRD09486
IPIIPI00103742   IPI00383250   IPI00103741   IPI00478191   IPI00167670   IPI01026587   IPI01022541   IPI01021141   IPI01022438   
Protein Interaction databases
DIP (DOE-UCLA)Q8WYL5
IntAct (EBI)Q8WYL5
FunCoupENSG00000084112
BioGRIDSSH1
STRING (EMBL)SSH1
ZODIACSSH1
Ontologies - Pathways
QuickGOQ8WYL5
Ontology : AmiGOcell morphogenesis  DNA binding  actin binding  phosphoprotein phosphatase activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleoplasm  cytoplasm  cytoskeleton  plasma membrane  protein dephosphorylation  regulation of actin polymerization or depolymerization  protein tyrosine/serine/threonine phosphatase activity  regulation of lamellipodium assembly  lamellipodium  actin cytoskeleton organization  midbody  cleavage furrow  regulation of cellular protein metabolic process  peptidyl-tyrosine dephosphorylation  regulation of axonogenesis  cellular response to ATP  
Ontology : EGO-EBIcell morphogenesis  DNA binding  actin binding  phosphoprotein phosphatase activity  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleoplasm  cytoplasm  cytoskeleton  plasma membrane  protein dephosphorylation  regulation of actin polymerization or depolymerization  protein tyrosine/serine/threonine phosphatase activity  regulation of lamellipodium assembly  lamellipodium  actin cytoskeleton organization  midbody  cleavage furrow  regulation of cellular protein metabolic process  peptidyl-tyrosine dephosphorylation  regulation of axonogenesis  cellular response to ATP  
Pathways : KEGGRegulation of actin cytoskeleton   
NDEx NetworkSSH1
Atlas of Cancer Signalling NetworkSSH1
Wikipedia pathwaysSSH1
Orthology - Evolution
OrthoDB54434
GeneTree (enSembl)ENSG00000084112
Phylogenetic Trees/Animal Genes : TreeFamSSH1
Homologs : HomoloGeneSSH1
Homology/Alignments : Family Browser (UCSC)SSH1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSSH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SSH1
dbVarSSH1
ClinVarSSH1
1000_GenomesSSH1 
Exome Variant ServerSSH1
ExAC (Exome Aggregation Consortium)SSH1 (select the gene name)
Genetic variants : HAPMAP54434
Genomic Variants (DGV)SSH1 [DGVbeta]
Mutations
ICGC Data PortalSSH1 
TCGA Data PortalSSH1 
Broad Tumor PortalSSH1
OASIS PortalSSH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSSH1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SSH1
DgiDB (Drug Gene Interaction Database)SSH1
DoCM (Curated mutations)SSH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SSH1 (select a term)
intoGenSSH1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:109185695-109251359  ENSG00000084112
CONAN: Copy Number AnalysisSSH1 
Mutations and Diseases : HGMDSSH1
OMIM606778   
MedgenSSH1
Genetic Testing Registry SSH1
NextProtQ8WYL5 [Medical]
TSGene54434
GENETestsSSH1
Huge Navigator SSH1 [HugePedia]
snp3D : Map Gene to Disease54434
BioCentury BCIQSSH1
ClinGenSSH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54434
Chemical/Pharm GKB GenePA134941788
Clinical trialSSH1
Miscellaneous
canSAR (ICR)SSH1 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSSH1
EVEXSSH1
GoPubMedSSH1
iHOPSSH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 19 19:15:01 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.