Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SSRP1 (structure specific recognition protein 1)

Identity

Alias (NCBI)FACT
FACT80
T160
HGNC (Hugo) SSRP1
HGNC Alias symbFACT80
HGNC Alias namefacilitates chromatin remodeling 80 kDa subunit
LocusID (NCBI) 6749
Atlas_Id 42400
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 57325989 and ends at 57335892 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CBX1 (17q21.32) / SSRP1 (11q12.1)FBXO34 (14q22.3) / SSRP1 (11q12.1)HEXB (5q13.3) / SSRP1 (11q12.1)
SSRP1 (11q12.1) / EIF3M (11p13)SSRP1 (11q12.1) / FADS2 (11q12.2)SSRP1 (11q12.1) / MED19 (11q12.1)
SSRP1 (11q12.1) / SSRP1 (11q12.1)SSRP1 (11q12.1) / TRMT2A (22q11.21)SSRP1 11q12.1 / MED19 11q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)SSRP1   11327
Cards
Entrez_Gene (NCBI)SSRP1    structure specific recognition protein 1
AliasesFACT; FACT80; T160
GeneCards (Weizmann)SSRP1
Ensembl hg19 (Hinxton)ENSG00000149136 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149136 [Gene_View]  ENSG00000149136 [Sequence]  chr11:57325989-57335892 [Contig_View]  SSRP1 [Vega]
ICGC DataPortalENSG00000149136
TCGA cBioPortalSSRP1
AceView (NCBI)SSRP1
Genatlas (Paris)SSRP1
SOURCE (Princeton)SSRP1
Genetics Home Reference (NIH)SSRP1
Genomic and cartography
GoldenPath hg38 (UCSC)SSRP1  -     chr11:57325989-57335892 -  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SSRP1  -     11q12.1   [Description]    (hg19-Feb_2009)
GoldenPathSSRP1 - 11q12.1 [CytoView hg19]  SSRP1 - 11q12.1 [CytoView hg38]
ImmunoBaseENSG00000149136
Genome Data Viewer NCBISSRP1 [Mapview hg19]  
OMIM604328   
Gene and transcription
Genbank (Entrez)AB209132 BC005116 BC091486 M86737
RefSeq transcript (Entrez)NM_003146
Consensus coding sequences : CCDS (NCBI)SSRP1
Gene ExpressionSSRP1 [ NCBI-GEO ]   SSRP1 [ EBI - ARRAY_EXPRESS ]   SSRP1 [ SEEK ]   SSRP1 [ MEM ]
Gene Expression Viewer (FireBrowse)SSRP1 [ Firebrowse - Broad ]
GenevisibleExpression of SSRP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6749
GTEX Portal (Tissue expression)SSRP1
Human Protein AtlasENSG00000149136-SSRP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08945   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ08945  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08945
PhosPhoSitePlusQ08945
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)DUF1747    HMG_box_dom    HMG_box_dom_sf    PH-like_dom_sf    POB3_N    SSrcognition    SSRP1_dom    SSRP1_sf   
Domain families : Pfam (Sanger)HMG_box (PF00505)    POB3_N (PF17292)    Rtt106 (PF08512)    SSrecog (PF03531)   
Domain families : Pfam (NCBI)pfam00505    pfam17292    pfam08512    pfam03531   
Domain families : Smart (EMBL)HMG (SM00398)  Rtt106 (SM01287)  
Conserved Domain (NCBI)SSRP1
PDB (RSDB)4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
PDB Europe4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
PDB (PDBSum)4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
PDB (IMB)4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
Structural Biology KnowledgeBase4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
SCOP (Structural Classification of Proteins)4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
CATH (Classification of proteins structures)4IFS    5UMR    5UMS    5VWE    6L1E    6L1R    6L34    6UPK    6UPL   
SuperfamilyQ08945
AlphaFold pdb e-kbQ08945   
Human Protein Atlas [tissue]ENSG00000149136-SSRP1 [tissue]
HPRD05061
Protein Interaction databases
DIP (DOE-UCLA)Q08945
IntAct (EBI)Q08945
BioGRIDSSRP1
STRING (EMBL)SSRP1
ZODIACSSRP1
Ontologies - Pathways
QuickGOQ08945
Ontology : AmiGODNA binding  RNA binding  protein binding  nucleoplasm  nucleolus  DNA replication  DNA repair  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  nucleosome binding  FACT complex  histone binding  regulation of signal transduction by p53 class mediator  regulation of chromatin organization  regulation of chromatin organization  
Ontology : EGO-EBIDNA binding  RNA binding  protein binding  nucleoplasm  nucleolus  DNA replication  DNA repair  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  nucleosome binding  FACT complex  histone binding  regulation of signal transduction by p53 class mediator  regulation of chromatin organization  regulation of chromatin organization  
NDEx NetworkSSRP1
Atlas of Cancer Signalling NetworkSSRP1
Wikipedia pathwaysSSRP1
Orthology - Evolution
OrthoDB6749
GeneTree (enSembl)ENSG00000149136
Phylogenetic Trees/Animal Genes : TreeFamSSRP1
Homologs : HomoloGeneSSRP1
Homology/Alignments : Family Browser (UCSC)SSRP1
Gene fusions - Rearrangements
Fusion : MitelmanSSRP1/MED19 [11q12.1/11q12.1]  
Fusion : QuiverSSRP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSSRP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SSRP1
dbVarSSRP1
ClinVarSSRP1
MonarchSSRP1
1000_GenomesSSRP1 
Exome Variant ServerSSRP1
GNOMAD BrowserENSG00000149136
Varsome BrowserSSRP1
ACMGSSRP1 variants
VarityQ08945
Genomic Variants (DGV)SSRP1 [DGVbeta]
DECIPHERSSRP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSSRP1 
Mutations
ICGC Data PortalSSRP1 
TCGA Data PortalSSRP1 
Broad Tumor PortalSSRP1
OASIS PortalSSRP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSSRP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSSRP1
Mutations and Diseases : HGMDSSRP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSSRP1
DgiDB (Drug Gene Interaction Database)SSRP1
DoCM (Curated mutations)SSRP1
CIViC (Clinical Interpretations of Variants in Cancer)SSRP1
Cancer3DSSRP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604328   
Orphanet
DisGeNETSSRP1
MedgenSSRP1
Genetic Testing Registry SSRP1
NextProtQ08945 [Medical]
GENETestsSSRP1
Target ValidationSSRP1
Huge Navigator SSRP1 [HugePedia]
ClinGenSSRP1
Clinical trials, drugs, therapy
MyCancerGenomeSSRP1
Protein Interactions : CTDSSRP1
Pharm GKB GenePA36151
PharosQ08945
Clinical trialSSRP1
Miscellaneous
canSAR (ICR)SSRP1
HarmonizomeSSRP1
DataMed IndexSSRP1
Probes
Litterature
PubMed197 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSSRP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:33:16 CEST 2021
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