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SSRP1 (structure specific recognition protein 1)

Identity

Alias_symbol (synonym)FACT80
Other aliasFACT
T160
HGNC (Hugo) SSRP1
LocusID (NCBI) 6749
Atlas_Id 42400
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 57325985 and ends at 57335877 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CBX1 (17q21.32) / SSRP1 (11q12.1)FBXO34 (14q22.3) / SSRP1 (11q12.1)HEXB (5q13.3) / SSRP1 (11q12.1)
SSRP1 (11q12.1) / EIF3M (11p13)SSRP1 (11q12.1) / FADS2 (11q12.2)SSRP1 (11q12.1) / MED19 (11q12.1)
SSRP1 (11q12.1) / SSRP1 (11q12.1)SSRP1 (11q12.1) / TRMT2A (22q11.21)SSRP1 11q12.1 / MED19 11q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;11)(q12;q12) SSRP1/MED19

External links

Nomenclature
HGNC (Hugo)SSRP1   11327
Cards
Entrez_Gene (NCBI)SSRP1  6749  structure specific recognition protein 1
AliasesFACT; FACT80; T160
GeneCards (Weizmann)SSRP1
Ensembl hg19 (Hinxton)ENSG00000149136 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149136 [Gene_View]  ENSG00000149136 [Sequence]  chr11:57325985-57335877 [Contig_View]  SSRP1 [Vega]
ICGC DataPortalENSG00000149136
TCGA cBioPortalSSRP1
AceView (NCBI)SSRP1
Genatlas (Paris)SSRP1
WikiGenes6749
SOURCE (Princeton)SSRP1
Genetics Home Reference (NIH)SSRP1
Genomic and cartography
GoldenPath hg38 (UCSC)SSRP1  -     chr11:57325985-57335877 -  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SSRP1  -     11q12.1   [Description]    (hg19-Feb_2009)
EnsemblSSRP1 - 11q12.1 [CytoView hg19]  SSRP1 - 11q12.1 [CytoView hg38]
Mapping of homologs : NCBISSRP1 [Mapview hg19]  SSRP1 [Mapview hg38]
OMIM604328   
Gene and transcription
Genbank (Entrez)AB209132 BC005116 BC091486 M86737
RefSeq transcript (Entrez)NM_003146
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SSRP1
Cluster EST : UnigeneHs.523680 [ NCBI ]
CGAP (NCI)Hs.523680
Alternative Splicing GalleryENSG00000149136
Gene ExpressionSSRP1 [ NCBI-GEO ]   SSRP1 [ EBI - ARRAY_EXPRESS ]   SSRP1 [ SEEK ]   SSRP1 [ MEM ]
Gene Expression Viewer (FireBrowse)SSRP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6749
GTEX Portal (Tissue expression)SSRP1
Human Protein AtlasENSG00000149136-SSRP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08945   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ08945  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08945
Splice isoforms : SwissVarQ08945
PhosPhoSitePlusQ08945
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)DUF1747    HMG_box_dom    PH_dom-like    SSrcognition    SSRP1_dom   
Domain families : Pfam (Sanger)HMG_box (PF00505)    Rtt106 (PF08512)    SSrecog (PF03531)   
Domain families : Pfam (NCBI)pfam00505    pfam08512    pfam03531   
Domain families : Smart (EMBL)HMG (SM00398)  Rtt106 (SM01287)  
Conserved Domain (NCBI)SSRP1
DMDM Disease mutations6749
Blocks (Seattle)SSRP1
PDB (SRS)4IFS   
PDB (PDBSum)4IFS   
PDB (IMB)4IFS   
PDB (RSDB)4IFS   
Structural Biology KnowledgeBase4IFS   
SCOP (Structural Classification of Proteins)4IFS   
CATH (Classification of proteins structures)4IFS   
SuperfamilyQ08945
Human Protein Atlas [tissue]ENSG00000149136-SSRP1 [tissue]
Peptide AtlasQ08945
HPRD05061
IPIIPI00005154   IPI00556260   IPI00985291   IPI00981139   
Protein Interaction databases
DIP (DOE-UCLA)Q08945
IntAct (EBI)Q08945
FunCoupENSG00000149136
BioGRIDSSRP1
STRING (EMBL)SSRP1
ZODIACSSRP1
Ontologies - Pathways
QuickGOQ08945
Ontology : AmiGODNA binding  chromatin binding  RNA binding  protein binding  nucleoplasm  chromosome  nucleolus  DNA replication  DNA repair  regulation of transcription, DNA-templated  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIDNA binding  chromatin binding  RNA binding  protein binding  nucleoplasm  chromosome  nucleolus  DNA replication  DNA repair  regulation of transcription, DNA-templated  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  regulation of signal transduction by p53 class mediator  
NDEx NetworkSSRP1
Atlas of Cancer Signalling NetworkSSRP1
Wikipedia pathwaysSSRP1
Orthology - Evolution
OrthoDB6749
GeneTree (enSembl)ENSG00000149136
Phylogenetic Trees/Animal Genes : TreeFamSSRP1
HOVERGENQ08945
HOGENOMQ08945
Homologs : HomoloGeneSSRP1
Homology/Alignments : Family Browser (UCSC)SSRP1
Gene fusions - Rearrangements
Fusion : MitelmanSSRP1/MED19 [11q12.1/11q12.1]  
Fusion PortalSSRP1 11q12.1 MED19 11q12.1 OV
Fusion : QuiverSSRP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSSRP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SSRP1
dbVarSSRP1
ClinVarSSRP1
1000_GenomesSSRP1 
Exome Variant ServerSSRP1
ExAC (Exome Aggregation Consortium)ENSG00000149136
GNOMAD BrowserENSG00000149136
Genetic variants : HAPMAP6749
Genomic Variants (DGV)SSRP1 [DGVbeta]
DECIPHERSSRP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSSRP1 
Mutations
ICGC Data PortalSSRP1 
TCGA Data PortalSSRP1 
Broad Tumor PortalSSRP1
OASIS PortalSSRP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSSRP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSSRP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SSRP1
DgiDB (Drug Gene Interaction Database)SSRP1
DoCM (Curated mutations)SSRP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SSRP1 (select a term)
intoGenSSRP1
Cancer3DSSRP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604328   
Orphanet
DisGeNETSSRP1
MedgenSSRP1
Genetic Testing Registry SSRP1
NextProtQ08945 [Medical]
TSGene6749
GENETestsSSRP1
Target ValidationSSRP1
Huge Navigator SSRP1 [HugePedia]
snp3D : Map Gene to Disease6749
BioCentury BCIQSSRP1
ClinGenSSRP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6749
Chemical/Pharm GKB GenePA36151
Clinical trialSSRP1
Miscellaneous
canSAR (ICR)SSRP1 (select the gene name)
Probes
Litterature
PubMed122 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSSRP1
EVEXSSRP1
GoPubMedSSRP1
iHOPSSRP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:51:54 CEST 2018
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