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SST (somatostatin)

Identity

Alias_symbol (synonym)SMST
Other alias
HGNC (Hugo) SST
LocusID (NCBI) 6750
Atlas_Id 45942
Location 3q27.3  [Link to chromosome band 3q27]
Location_base_pair Starts at 187668906 and ends at 187670413 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANKRD52 (12q13.3) / SST (3q27.3)SST (3q27.3) / ANKRD52 (12q13.3)SST (3q27.3) / NASP (1p34.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SST   11329
Cards
Entrez_Gene (NCBI)SST  6750  somatostatin
AliasesSMST
GeneCards (Weizmann)SST
Ensembl hg19 (Hinxton)ENSG00000157005 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157005 [Gene_View]  chr3:187668906-187670413 [Contig_View]  SST [Vega]
ICGC DataPortalENSG00000157005
TCGA cBioPortalSST
AceView (NCBI)SST
Genatlas (Paris)SST
WikiGenes6750
SOURCE (Princeton)SST
Genetics Home Reference (NIH)SST
Genomic and cartography
GoldenPath hg38 (UCSC)SST  -     chr3:187668906-187670413 -  3q27.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SST  -     3q27.3   [Description]    (hg19-Feb_2009)
EnsemblSST - 3q27.3 [CytoView hg19]  SST - 3q27.3 [CytoView hg38]
Mapping of homologs : NCBISST [Mapview hg19]  SST [Mapview hg38]
OMIM182450   
Gene and transcription
Genbank (Entrez)AK312177 BC032625 BM353331 R54287
RefSeq transcript (Entrez)NM_001048
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SST
Cluster EST : UnigeneHs.12409 [ NCBI ]
CGAP (NCI)Hs.12409
Alternative Splicing GalleryENSG00000157005
Gene ExpressionSST [ NCBI-GEO ]   SST [ EBI - ARRAY_EXPRESS ]   SST [ SEEK ]   SST [ MEM ]
Gene Expression Viewer (FireBrowse)SST [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6750
GTEX Portal (Tissue expression)SST
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61278   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61278  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61278
Splice isoforms : SwissVarP61278
PhosPhoSitePlusP61278
Domains : Interpro (EBI)Somatostatin    Somatostatin/Cortistatin_C   
Domain families : Pfam (Sanger)Somatostatin (PF03002)   
Domain families : Pfam (NCBI)pfam03002   
Conserved Domain (NCBI)SST
DMDM Disease mutations6750
Blocks (Seattle)SST
PDB (SRS)1P2W    2MI1   
PDB (PDBSum)1P2W    2MI1   
PDB (IMB)1P2W    2MI1   
PDB (RSDB)1P2W    2MI1   
Structural Biology KnowledgeBase1P2W    2MI1   
SCOP (Structural Classification of Proteins)1P2W    2MI1   
CATH (Classification of proteins structures)1P2W    2MI1   
SuperfamilyP61278
Human Protein AtlasENSG00000157005
Peptide AtlasP61278
HPRD08920
IPIIPI00000130   
Protein Interaction databases
DIP (DOE-UCLA)P61278
IntAct (EBI)P61278
FunCoupENSG00000157005
BioGRIDSST
STRING (EMBL)SST
ZODIACSST
Ontologies - Pathways
QuickGOP61278
Ontology : AmiGOhormone activity  extracellular region  extracellular space  hyperosmotic response  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  cell-cell signaling  chemical synaptic transmission  response to nutrient  digestion  negative regulation of cell proliferation  hormone-mediated apoptotic signaling pathway  response to heat  response to acidic pH  regulation of cell migration  response to drug  neuronal cell body  response to amino acid  response to steroid hormone  
Ontology : EGO-EBIhormone activity  extracellular region  extracellular space  hyperosmotic response  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  cell-cell signaling  chemical synaptic transmission  response to nutrient  digestion  negative regulation of cell proliferation  hormone-mediated apoptotic signaling pathway  response to heat  response to acidic pH  regulation of cell migration  response to drug  neuronal cell body  response to amino acid  response to steroid hormone  
Pathways : BIOCARTAGhrelin: Regulation of Food Intake and Energy Homeostasis [Genes]   
Pathways : KEGGGastric acid secretion   
NDEx NetworkSST
Atlas of Cancer Signalling NetworkSST
Wikipedia pathwaysSST
Orthology - Evolution
OrthoDB6750
GeneTree (enSembl)ENSG00000157005
Phylogenetic Trees/Animal Genes : TreeFamSST
HOVERGENP61278
HOGENOMP61278
Homologs : HomoloGeneSST
Homology/Alignments : Family Browser (UCSC)SST
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSST [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SST
dbVarSST
ClinVarSST
1000_GenomesSST 
Exome Variant ServerSST
ExAC (Exome Aggregation Consortium)SST (select the gene name)
Genetic variants : HAPMAP6750
Genomic Variants (DGV)SST [DGVbeta]
DECIPHERSST [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSST 
Mutations
ICGC Data PortalSST 
TCGA Data PortalSST 
Broad Tumor PortalSST
OASIS PortalSST [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSST  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSST
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SST
DgiDB (Drug Gene Interaction Database)SST
DoCM (Curated mutations)SST (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SST (select a term)
intoGenSST
Cancer3DSST(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182450   
Orphanet
MedgenSST
Genetic Testing Registry SST
NextProtP61278 [Medical]
TSGene6750
GENETestsSST
Target ValidationSST
Huge Navigator SST [HugePedia]
snp3D : Map Gene to Disease6750
BioCentury BCIQSST
ClinGenSST
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6750
Chemical/Pharm GKB GenePA36153
Clinical trialSST
Miscellaneous
canSAR (ICR)SST (select the gene name)
Probes
Litterature
PubMed95 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSST
EVEXSST
GoPubMedSST
iHOPSST
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:08:35 CEST 2017

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