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SSTR2 (somatostatin receptor 2)

Identity

Other alias-
HGNC (Hugo) SSTR2
LocusID (NCBI) 6752
Atlas_Id 42402
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 73165021 and ends at 73171923 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SSTR2   11331
Cards
Entrez_Gene (NCBI)SSTR2  6752  somatostatin receptor 2
Aliases
GeneCards (Weizmann)SSTR2
Ensembl hg19 (Hinxton)ENSG00000180616 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180616 [Gene_View]  chr17:73165021-73171923 [Contig_View]  SSTR2 [Vega]
ICGC DataPortalENSG00000180616
TCGA cBioPortalSSTR2
AceView (NCBI)SSTR2
Genatlas (Paris)SSTR2
WikiGenes6752
SOURCE (Princeton)SSTR2
Genetics Home Reference (NIH)SSTR2
Genomic and cartography
GoldenPath hg38 (UCSC)SSTR2  -     chr17:73165021-73171923 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SSTR2  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblSSTR2 - 17q25.1 [CytoView hg19]  SSTR2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBISSTR2 [Mapview hg19]  SSTR2 [Mapview hg38]
OMIM182452   
Gene and transcription
Genbank (Entrez)AK093950 AK290745 AK313866 BC000256 BC009522
RefSeq transcript (Entrez)NM_001050
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SSTR2
Cluster EST : UnigeneHs.514451 [ NCBI ]
CGAP (NCI)Hs.514451
Alternative Splicing GalleryENSG00000180616
Gene ExpressionSSTR2 [ NCBI-GEO ]   SSTR2 [ EBI - ARRAY_EXPRESS ]   SSTR2 [ SEEK ]   SSTR2 [ MEM ]
Gene Expression Viewer (FireBrowse)SSTR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6752
GTEX Portal (Tissue expression)SSTR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30874   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30874  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30874
Splice isoforms : SwissVarP30874
PhosPhoSitePlusP30874
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Somatstn_rcpt    Somatstn_rcpt_2   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)SSTR2
DMDM Disease mutations6752
Blocks (Seattle)SSTR2
SuperfamilyP30874
Human Protein AtlasENSG00000180616
Peptide AtlasP30874
HPRD01674
IPIIPI00027807   IPI00046027   
Protein Interaction databases
DIP (DOE-UCLA)P30874
IntAct (EBI)P30874
FunCoupENSG00000180616
BioGRIDSSTR2
STRING (EMBL)SSTR2
ZODIACSSTR2
Ontologies - Pathways
QuickGOP30874
Ontology : AmiGOsomatostatin receptor activity  protein binding  cytosol  plasma membrane  integral component of plasma membrane  regulation of muscle contraction  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  cell-cell signaling  spermatogenesis  response to nutrient  digestion  negative regulation of cell proliferation  cerebellum development  PDZ domain binding  peristalsis  forebrain development  somatostatin signaling pathway  response to starvation  neuropeptide binding  neuron projection  cellular response to glucocorticoid stimulus  cellular response to estradiol stimulus  
Ontology : EGO-EBIsomatostatin receptor activity  protein binding  cytosol  plasma membrane  integral component of plasma membrane  regulation of muscle contraction  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  cell-cell signaling  spermatogenesis  response to nutrient  digestion  negative regulation of cell proliferation  cerebellum development  PDZ domain binding  peristalsis  forebrain development  somatostatin signaling pathway  response to starvation  neuropeptide binding  neuron projection  cellular response to glucocorticoid stimulus  cellular response to estradiol stimulus  
Pathways : KEGGNeuroactive ligand-receptor interaction    Gastric acid secretion   
NDEx NetworkSSTR2
Atlas of Cancer Signalling NetworkSSTR2
Wikipedia pathwaysSSTR2
Orthology - Evolution
OrthoDB6752
GeneTree (enSembl)ENSG00000180616
Phylogenetic Trees/Animal Genes : TreeFamSSTR2
HOVERGENP30874
HOGENOMP30874
Homologs : HomoloGeneSSTR2
Homology/Alignments : Family Browser (UCSC)SSTR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSSTR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SSTR2
dbVarSSTR2
ClinVarSSTR2
1000_GenomesSSTR2 
Exome Variant ServerSSTR2
ExAC (Exome Aggregation Consortium)SSTR2 (select the gene name)
Genetic variants : HAPMAP6752
Genomic Variants (DGV)SSTR2 [DGVbeta]
DECIPHERSSTR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSSTR2 
Mutations
ICGC Data PortalSSTR2 
TCGA Data PortalSSTR2 
Broad Tumor PortalSSTR2
OASIS PortalSSTR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSSTR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSSTR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SSTR2
DgiDB (Drug Gene Interaction Database)SSTR2
DoCM (Curated mutations)SSTR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SSTR2 (select a term)
intoGenSSTR2
Cancer3DSSTR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182452   
Orphanet
MedgenSSR2<.TD>
Genetic Testing Registry SSTR2
NextProtP30874 [Medical]
TSGene6752
GENETestsSSTR2
Target ValidationSSTR2
Huge Navigator SSTR2 [HugePedia]
snp3D : Map Gene to Disease6752
BioCentury BCIQSSTR2
ClinGenSSTR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6752
Chemical/Pharm GKB GenePA36155
Clinical trialSSTR2
Miscellaneous
canSAR (ICR)SSTR2 (select the gene name)
Probes
Litterature
PubMed164 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSSTR2
EVEXSSTR2
GoPubMedSSTR2
iHOPSSTR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:09 CEST 2017

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