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ST3GAL2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2)

Identity

Alias_namesSIAT4B
sialyltransferase 4B (beta-galactosidase alpha-2
Alias_symbol (synonym)ST3GALII
ST3GalA.2
Other aliasGal-NAc6S
HGNC (Hugo) ST3GAL2
LocusID (NCBI) 6483
Atlas_Id 50652
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 70379435 and ends at 70439088 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AARS (16q22.1) / ST3GAL2 (16q22.1)BASP1 (5p15.1) / ST3GAL2 (16q22.1)CYBA (16q24.3) / ST3GAL2 (16q22.1)
IL34 (16q22.1) / ST3GAL2 (16q22.1)ST3GAL2 (16q22.1) / COG4 (16q22.1)AARS 16q22.1 / ST3GAL2 16q22.1
IL34 16q22.1 / ST3GAL2 16q22.1ST3GAL2 16q22.1 / COG4 16q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST3GAL2   10863
Cards
Entrez_Gene (NCBI)ST3GAL2  6483  ST3 beta-galactoside alpha-2,3-sialyltransferase 2
AliasesGal-NAc6S; SIAT4B; ST3GALII; ST3GalA.2
GeneCards (Weizmann)ST3GAL2
Ensembl hg19 (Hinxton)ENSG00000157350 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157350 [Gene_View]  chr16:70379435-70439088 [Contig_View]  ST3GAL2 [Vega]
ICGC DataPortalENSG00000157350
TCGA cBioPortalST3GAL2
AceView (NCBI)ST3GAL2
Genatlas (Paris)ST3GAL2
WikiGenes6483
SOURCE (Princeton)ST3GAL2
Genetics Home Reference (NIH)ST3GAL2
Genomic and cartography
GoldenPath hg38 (UCSC)ST3GAL2  -     chr16:70379435-70439088 -  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ST3GAL2  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblST3GAL2 - 16q22.1 [CytoView hg19]  ST3GAL2 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBIST3GAL2 [Mapview hg19]  ST3GAL2 [Mapview hg38]
OMIM607188   
Gene and transcription
Genbank (Entrez)AF086257 AI933719 AK127322 AK313020 BC036777
RefSeq transcript (Entrez)NM_006927
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ST3GAL2
Cluster EST : UnigeneHs.368611 [ NCBI ]
CGAP (NCI)Hs.368611
Alternative Splicing GalleryENSG00000157350
Gene ExpressionST3GAL2 [ NCBI-GEO ]   ST3GAL2 [ EBI - ARRAY_EXPRESS ]   ST3GAL2 [ SEEK ]   ST3GAL2 [ MEM ]
Gene Expression Viewer (FireBrowse)ST3GAL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6483
GTEX Portal (Tissue expression)ST3GAL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16842   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16842  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16842
Splice isoforms : SwissVarQ16842
Catalytic activity : Enzyme2.4.99.4 [ Enzyme-Expasy ]   2.4.99.42.4.99.4 [ IntEnz-EBI ]   2.4.99.4 [ BRENDA ]   2.4.99.4 [ KEGG ]   
PhosPhoSitePlusQ16842
Domains : Interpro (EBI)Glyco_trans_29    Sialyl_trans   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST3GAL2
DMDM Disease mutations6483
Blocks (Seattle)ST3GAL2
SuperfamilyQ16842
Human Protein AtlasENSG00000157350
Peptide AtlasQ16842
HPRD06220
IPIIPI00012620   
Protein Interaction databases
DIP (DOE-UCLA)Q16842
IntAct (EBI)Q16842
FunCoupENSG00000157350
BioGRIDST3GAL2
STRING (EMBL)ST3GAL2
ZODIACST3GAL2
Ontologies - Pathways
QuickGOQ16842
Ontology : AmiGOGolgi membrane  beta-galactoside (CMP) alpha-2,3-sialyltransferase activity  beta-galactoside (CMP) alpha-2,3-sialyltransferase activity  extracellular region  amino sugar metabolic process  cellular protein modification process  oligosaccharide metabolic process  O-glycan processing  keratan sulfate biosynthetic process  protein N-linked glycosylation via asparagine  integral component of Golgi membrane  Golgi cisterna membrane  sialylation  
Ontology : EGO-EBIGolgi membrane  beta-galactoside (CMP) alpha-2,3-sialyltransferase activity  beta-galactoside (CMP) alpha-2,3-sialyltransferase activity  extracellular region  amino sugar metabolic process  cellular protein modification process  oligosaccharide metabolic process  O-glycan processing  keratan sulfate biosynthetic process  protein N-linked glycosylation via asparagine  integral component of Golgi membrane  Golgi cisterna membrane  sialylation  
Pathways : KEGGMucin type O-Glycan biosynthesis    Glycosaminoglycan biosynthesis - keratan sulfate    Glycosphingolipid biosynthesis - globo series    Glycosphingolipid biosynthesis - ganglio series   
NDEx NetworkST3GAL2
Atlas of Cancer Signalling NetworkST3GAL2
Wikipedia pathwaysST3GAL2
Orthology - Evolution
OrthoDB6483
GeneTree (enSembl)ENSG00000157350
Phylogenetic Trees/Animal Genes : TreeFamST3GAL2
HOVERGENQ16842
HOGENOMQ16842
Homologs : HomoloGeneST3GAL2
Homology/Alignments : Family Browser (UCSC)ST3GAL2
Gene fusions - Rearrangements
Fusion : MitelmanAARS/ST3GAL2 [16q22.1/16q22.1]  [t(16;16)(q22;q22)]  
Fusion : MitelmanIL34/ST3GAL2 [16q22.1/16q22.1]  [t(16;16)(q22;q22)]  
Fusion : MitelmanST3GAL2/COG4 [16q22.1/16q22.1]  [t(16;16)(q22;q22)]  
Fusion: TCGAAARS 16q22.1 ST3GAL2 16q22.1 BRCA
Fusion: TCGAIL34 16q22.1 ST3GAL2 16q22.1 LUAD
Fusion: TCGAST3GAL2 16q22.1 COG4 16q22.1 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST3GAL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST3GAL2
dbVarST3GAL2
ClinVarST3GAL2
1000_GenomesST3GAL2 
Exome Variant ServerST3GAL2
ExAC (Exome Aggregation Consortium)ST3GAL2 (select the gene name)
Genetic variants : HAPMAP6483
Genomic Variants (DGV)ST3GAL2 [DGVbeta]
DECIPHERST3GAL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisST3GAL2 
Mutations
ICGC Data PortalST3GAL2 
TCGA Data PortalST3GAL2 
Broad Tumor PortalST3GAL2
OASIS PortalST3GAL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST3GAL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST3GAL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST3GAL2
DgiDB (Drug Gene Interaction Database)ST3GAL2
DoCM (Curated mutations)ST3GAL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST3GAL2 (select a term)
intoGenST3GAL2
Cancer3DST3GAL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607188   
Orphanet
MedgenST3GAL2
Genetic Testing Registry ST3GAL2
NextProtQ16842 [Medical]
TSGene6483
GENETestsST3GAL2
Target ValidationST3GAL2
Huge Navigator ST3GAL2 [HugePedia]
snp3D : Map Gene to Disease6483
BioCentury BCIQST3GAL2
ClinGenST3GAL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6483
Chemical/Pharm GKB GenePA35765
Clinical trialST3GAL2
Miscellaneous
canSAR (ICR)ST3GAL2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST3GAL2
EVEXST3GAL2
GoPubMedST3GAL2
iHOPST3GAL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Aug 1 17:15:52 CEST 2017

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