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ST6GAL2 (ST6 beta-galactosamide alpha-2,6-sialyltranferase 2)

Identity

Alias_namesSIAT2
sialyltransferase 2 (monosialoganglioside sialyltransferase)
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
Alias_symbol (synonym)KIAA1877
St6gal2
St6GalII
Other aliasST6GalII
HGNC (Hugo) ST6GAL2
LocusID (NCBI) 84620
Atlas_Id 74270
Location 2q12.2  [Link to chromosome band 2q12]
Location_base_pair Starts at 107418056 and ends at 107502610 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LARGE (22q12.3) / ST6GAL2 (2q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST6GAL2   10861
Cards
Entrez_Gene (NCBI)ST6GAL2  84620  ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
AliasesSIAT2; ST6GalII
GeneCards (Weizmann)ST6GAL2
Ensembl hg19 (Hinxton)ENSG00000144057 [Gene_View]  chr2:107418056-107502610 [Contig_View]  ST6GAL2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000144057 [Gene_View]  chr2:107418056-107502610 [Contig_View]  ST6GAL2 [Vega]
ICGC DataPortalENSG00000144057
TCGA cBioPortalST6GAL2
AceView (NCBI)ST6GAL2
Genatlas (Paris)ST6GAL2
WikiGenes84620
SOURCE (Princeton)ST6GAL2
Genetics Home Reference (NIH)ST6GAL2
Genomic and cartography
GoldenPath hg19 (UCSC)ST6GAL2  -     chr2:107418056-107502610 -  2q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ST6GAL2  -     2q12.2   [Description]    (hg38-Dec_2013)
EnsemblST6GAL2 - 2q12.2 [CytoView hg19]  ST6GAL2 - 2q12.2 [CytoView hg38]
Mapping of homologs : NCBIST6GAL2 [Mapview hg19]  ST6GAL2 [Mapview hg38]
OMIM608472   
Gene and transcription
Genbank (Entrez)AB058780 AB059555 AJ512141 AK055273 AK095049
RefSeq transcript (Entrez)NM_001142351 NM_001142352 NM_032528
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_031986 NT_005403 NW_004929303
Consensus coding sequences : CCDS (NCBI)ST6GAL2
Cluster EST : UnigeneHs.98265 [ NCBI ]
CGAP (NCI)Hs.98265
Alternative Splicing GalleryENSG00000144057
Gene ExpressionST6GAL2 [ NCBI-GEO ]   ST6GAL2 [ EBI - ARRAY_EXPRESS ]   ST6GAL2 [ SEEK ]   ST6GAL2 [ MEM ]
Gene Expression Viewer (FireBrowse)ST6GAL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84620
GTEX Portal (Tissue expression)ST6GAL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JF0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JF0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JF0
Splice isoforms : SwissVarQ96JF0
Catalytic activity : Enzyme2.4.99.1 [ Enzyme-Expasy ]   2.4.99.12.4.99.1 [ IntEnz-EBI ]   2.4.99.1 [ BRENDA ]   2.4.99.1 [ KEGG ]   
PhosPhoSitePlusQ96JF0
Domains : Interpro (EBI)Glyco_hydro/deAcase_b/a-brl    Glyco_trans_29   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST6GAL2
DMDM Disease mutations84620
Blocks (Seattle)ST6GAL2
SuperfamilyQ96JF0
Human Protein AtlasENSG00000144057
Peptide AtlasQ96JF0
HPRD12237
IPIIPI00479942   IPI00063048   IPI00917855   IPI00916905   
Protein Interaction databases
DIP (DOE-UCLA)Q96JF0
IntAct (EBI)Q96JF0
FunCoupENSG00000144057
BioGRIDST6GAL2
STRING (EMBL)ST6GAL2
ZODIACST6GAL2
Ontologies - Pathways
QuickGOQ96JF0
Ontology : AmiGOGolgi membrane  beta-galactoside alpha-2,6-sialyltransferase activity  dolichol-linked oligosaccharide biosynthetic process  multicellular organismal development  oligosaccharide metabolic process  integral component of membrane  protein N-linked glycosylation via asparagine  Golgi cisterna membrane  growth  post-translational protein modification  cellular protein metabolic process  sialylation  sialylation  
Ontology : EGO-EBIGolgi membrane  beta-galactoside alpha-2,6-sialyltransferase activity  dolichol-linked oligosaccharide biosynthetic process  multicellular organismal development  oligosaccharide metabolic process  integral component of membrane  protein N-linked glycosylation via asparagine  Golgi cisterna membrane  growth  post-translational protein modification  cellular protein metabolic process  sialylation  sialylation  
Pathways : KEGGN-Glycan biosynthesis    Other types of O-glycan biosynthesis   
NDEx NetworkST6GAL2
Atlas of Cancer Signalling NetworkST6GAL2
Wikipedia pathwaysST6GAL2
Orthology - Evolution
OrthoDB84620
GeneTree (enSembl)ENSG00000144057
Phylogenetic Trees/Animal Genes : TreeFamST6GAL2
HOVERGENQ96JF0
HOGENOMQ96JF0
Homologs : HomoloGeneST6GAL2
Homology/Alignments : Family Browser (UCSC)ST6GAL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST6GAL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST6GAL2
dbVarST6GAL2
ClinVarST6GAL2
1000_GenomesST6GAL2 
Exome Variant ServerST6GAL2
ExAC (Exome Aggregation Consortium)ST6GAL2 (select the gene name)
Genetic variants : HAPMAP84620
Genomic Variants (DGV)ST6GAL2 [DGVbeta]
DECIPHER (Syndromes)2:107418056-107502610  ENSG00000144057
CONAN: Copy Number AnalysisST6GAL2 
Mutations
ICGC Data PortalST6GAL2 
TCGA Data PortalST6GAL2 
Broad Tumor PortalST6GAL2
OASIS PortalST6GAL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST6GAL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST6GAL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST6GAL2
DgiDB (Drug Gene Interaction Database)ST6GAL2
DoCM (Curated mutations)ST6GAL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST6GAL2 (select a term)
intoGenST6GAL2
Cancer3DST6GAL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608472   
Orphanet
MedgenST6GAL2
Genetic Testing Registry ST6GAL2
NextProtQ96JF0 [Medical]
TSGene84620
GENETestsST6GAL2
Huge Navigator ST6GAL2 [HugePedia]
snp3D : Map Gene to Disease84620
BioCentury BCIQST6GAL2
ClinGenST6GAL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84620
Chemical/Pharm GKB GenePA35763
Clinical trialST6GAL2
Miscellaneous
canSAR (ICR)ST6GAL2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST6GAL2
EVEXST6GAL2
GoPubMedST6GAL2
iHOPST6GAL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:46:48 CET 2017

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