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ST6GALNAC2 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2)

Identity

Alias_namesSIAT7
SIAT7B
SIATL1
sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase)
sialyltransferase-like 1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6 GalNAc alpha-2,6-sialyltransferase 2
Alias_symbol (synonym)ST6GalNAII
STHM
Other aliasSAITL1
HGNC (Hugo) ST6GALNAC2
LocusID (NCBI) 10610
Atlas_Id 54978
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 76565379 and ends at 76586063 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PRKCA (17q24.2) / ST6GALNAC2 (17q25.1)PRPSAP1 (17q25.1) / ST6GALNAC2 (17q25.1)ST6GALNAC2 (17q25.1) / JMJD6 (17q25.1)
VCAN (5q14.2) / ST6GALNAC2 (17q25.1)PRKCA 17q24.2 / ST6GALNAC2 17q25.1PRPSAP1 17q25.1 / ST6GALNAC2 17q25.1
ST6GALNAC2 17q25.1 / JMJD6 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST6GALNAC2   10867
Cards
Entrez_Gene (NCBI)ST6GALNAC2  10610  ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
AliasesSAITL1; SIAT7; SIAT7B; SIATL1; 
ST6GalNAII; STHM
GeneCards (Weizmann)ST6GALNAC2
Ensembl hg19 (Hinxton)ENSG00000070731 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070731 [Gene_View]  chr17:76565379-76586063 [Contig_View]  ST6GALNAC2 [Vega]
ICGC DataPortalENSG00000070731
TCGA cBioPortalST6GALNAC2
AceView (NCBI)ST6GALNAC2
Genatlas (Paris)ST6GALNAC2
WikiGenes10610
SOURCE (Princeton)ST6GALNAC2
Genetics Home Reference (NIH)ST6GALNAC2
Genomic and cartography
GoldenPath hg38 (UCSC)ST6GALNAC2  -     chr17:76565379-76586063 -  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ST6GALNAC2  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblST6GALNAC2 - 17q25.1 [CytoView hg19]  ST6GALNAC2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIST6GALNAC2 [Mapview hg19]  ST6GALNAC2 [Mapview hg38]
OMIM610137   
Gene and transcription
Genbank (Entrez)AJ251053 AK127567 AK225943 BC038114 BC040455
RefSeq transcript (Entrez)NM_006456
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ST6GALNAC2
Cluster EST : UnigeneHs.592105 [ NCBI ]
CGAP (NCI)Hs.592105
Alternative Splicing GalleryENSG00000070731
Gene ExpressionST6GALNAC2 [ NCBI-GEO ]   ST6GALNAC2 [ EBI - ARRAY_EXPRESS ]   ST6GALNAC2 [ SEEK ]   ST6GALNAC2 [ MEM ]
Gene Expression Viewer (FireBrowse)ST6GALNAC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10610
GTEX Portal (Tissue expression)ST6GALNAC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJ37   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJ37  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJ37
Splice isoforms : SwissVarQ9UJ37
Catalytic activity : Enzyme2.4.99.- [ Enzyme-Expasy ]   2.4.99.-2.4.99.- [ IntEnz-EBI ]   2.4.99.- [ BRENDA ]   2.4.99.- [ KEGG ]   
PhosPhoSitePlusQ9UJ37
Domains : Interpro (EBI)Glyco_trans_29    Sialyl_trans   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST6GALNAC2
DMDM Disease mutations10610
Blocks (Seattle)ST6GALNAC2
SuperfamilyQ9UJ37
Human Protein AtlasENSG00000070731
Peptide AtlasQ9UJ37
HPRD10231
IPIIPI00296495   IPI00977281   IPI00976157   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJ37
IntAct (EBI)Q9UJ37
FunCoupENSG00000070731
BioGRIDST6GALNAC2
STRING (EMBL)ST6GALNAC2
ZODIACST6GALNAC2
Ontologies - Pathways
QuickGOQ9UJ37
Ontology : AmiGOGolgi membrane  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity  sialyltransferase activity  sialyltransferase activity  oligosaccharide metabolic process  O-glycan processing  protein N-linked glycosylation via asparagine  integral component of Golgi membrane  sialylation  
Ontology : EGO-EBIGolgi membrane  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity  sialyltransferase activity  sialyltransferase activity  oligosaccharide metabolic process  O-glycan processing  protein N-linked glycosylation via asparagine  integral component of Golgi membrane  sialylation  
NDEx NetworkST6GALNAC2
Atlas of Cancer Signalling NetworkST6GALNAC2
Wikipedia pathwaysST6GALNAC2
Orthology - Evolution
OrthoDB10610
GeneTree (enSembl)ENSG00000070731
Phylogenetic Trees/Animal Genes : TreeFamST6GALNAC2
HOVERGENQ9UJ37
HOGENOMQ9UJ37
Homologs : HomoloGeneST6GALNAC2
Homology/Alignments : Family Browser (UCSC)ST6GALNAC2
Gene fusions - Rearrangements
Fusion : MitelmanPRKCA/ST6GALNAC2 [17q24.2/17q25.1]  [t(17;17)(q24;q25)]  
Fusion : MitelmanPRPSAP1/ST6GALNAC2 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanST6GALNAC2/JMJD6 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion: TCGAPRKCA 17q24.2 ST6GALNAC2 17q25.1 BRCA
Fusion: TCGAPRPSAP1 17q25.1 ST6GALNAC2 17q25.1 BRCA
Fusion: TCGAST6GALNAC2 17q25.1 JMJD6 17q25.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST6GALNAC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST6GALNAC2
dbVarST6GALNAC2
ClinVarST6GALNAC2
1000_GenomesST6GALNAC2 
Exome Variant ServerST6GALNAC2
ExAC (Exome Aggregation Consortium)ST6GALNAC2 (select the gene name)
Genetic variants : HAPMAP10610
Genomic Variants (DGV)ST6GALNAC2 [DGVbeta]
DECIPHERST6GALNAC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisST6GALNAC2 
Mutations
ICGC Data PortalST6GALNAC2 
TCGA Data PortalST6GALNAC2 
Broad Tumor PortalST6GALNAC2
OASIS PortalST6GALNAC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST6GALNAC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST6GALNAC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST6GALNAC2
DgiDB (Drug Gene Interaction Database)ST6GALNAC2
DoCM (Curated mutations)ST6GALNAC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST6GALNAC2 (select a term)
intoGenST6GALNAC2
Cancer3DST6GALNAC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610137   
Orphanet
MedgenST6GALNAC2
Genetic Testing Registry ST6GALNAC2
NextProtQ9UJ37 [Medical]
TSGene10610
GENETestsST6GALNAC2
Target ValidationST6GALNAC2
Huge Navigator ST6GALNAC2 [HugePedia]
snp3D : Map Gene to Disease10610
BioCentury BCIQST6GALNAC2
ClinGenST6GALNAC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10610
Chemical/Pharm GKB GenePA35769
Clinical trialST6GALNAC2
Miscellaneous
canSAR (ICR)ST6GALNAC2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST6GALNAC2
EVEXST6GALNAC2
GoPubMedST6GALNAC2
iHOPST6GALNAC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:08:43 CEST 2017

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