ST6GALNAC6 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6)

2014-11-01  

Identity

HGNC
ST6GALNAC6
LOCATION
9q34.11
LOCUSID
30815
ALIAS
SIAT7-F,SIAT7F,ST6GALNACVI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 30815
MIM: 610135
HGNC: 23364
Ensembl: ENSG00000257524

Variants:

dbSNP: 30815
ClinVar: 30815
TCGA: ENSG00000257524
COSMIC: ST6GALNAC6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000257524ENST00000643029A0A024R8C6
ENSG00000257524ENST00000643338A0A024R8C6
ENSG00000257524ENST00000645007A0A0S2Z653
ENSG00000257524ENST00000646171A0A2R8YFX0

Pathways

PathwaySourceExternal ID
Glycosphingolipid biosynthesis - ganglio seriesKEGGko00604
Glycosphingolipid biosynthesis - ganglio seriesKEGGhsa00604
Metabolic pathwaysKEGGhsa01100
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
Sialic acid metabolismREACTOMER-HSA-4085001

References

Pubmed IDYearTitleCitations
126686752003Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.23
171233522007Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers.9

Citation

Dessen P

ST6GALNAC6 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74275/st6galnac6