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ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2)

Identity

Alias_namesSIAT8B
sialyltransferase 8 (alpha-2, 8-sialytransferase) B
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 2
Alias_symbol (synonym)STX
ST8SIA-II
HsT19690
Other aliasSIAT8-B
ST8SiaII
HGNC (Hugo) ST8SIA2
LocusID (NCBI) 8128
Atlas_Id 43663
Location 15q26.1  [Link to chromosome band 15q26]
Location_base_pair Starts at 92393887 and ends at 92468728 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ST8SIA2 (15q26.1) / ST8SIA2 (15q26.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST8SIA2   10870
Cards
Entrez_Gene (NCBI)ST8SIA2  8128  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
AliasesHsT19690; SIAT8-B; SIAT8B; ST8SIA-II; 
ST8SiaII; STX
GeneCards (Weizmann)ST8SIA2
Ensembl hg19 (Hinxton)ENSG00000140557 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140557 [Gene_View]  chr15:92393887-92468728 [Contig_View]  ST8SIA2 [Vega]
ICGC DataPortalENSG00000140557
TCGA cBioPortalST8SIA2
AceView (NCBI)ST8SIA2
Genatlas (Paris)ST8SIA2
WikiGenes8128
SOURCE (Princeton)ST8SIA2
Genetics Home Reference (NIH)ST8SIA2
Genomic and cartography
GoldenPath hg38 (UCSC)ST8SIA2  -     chr15:92393887-92468728 +  15q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ST8SIA2  -     15q26.1   [Description]    (hg19-Feb_2009)
EnsemblST8SIA2 - 15q26.1 [CytoView hg19]  ST8SIA2 - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBIST8SIA2 [Mapview hg19]  ST8SIA2 [Mapview hg38]
OMIM602546   
Gene and transcription
Genbank (Entrez)AK313924 AW163487 AY358091 BC069584 BC096202
RefSeq transcript (Entrez)NM_001330416 NM_006011
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ST8SIA2
Cluster EST : UnigeneHs.302341 [ NCBI ]
CGAP (NCI)Hs.302341
Alternative Splicing GalleryENSG00000140557
Gene ExpressionST8SIA2 [ NCBI-GEO ]   ST8SIA2 [ EBI - ARRAY_EXPRESS ]   ST8SIA2 [ SEEK ]   ST8SIA2 [ MEM ]
Gene Expression Viewer (FireBrowse)ST8SIA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8128
GTEX Portal (Tissue expression)ST8SIA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92186   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92186  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92186
Splice isoforms : SwissVarQ92186
Catalytic activity : Enzyme2.4.99.- [ Enzyme-Expasy ]   2.4.99.-2.4.99.- [ IntEnz-EBI ]   2.4.99.- [ BRENDA ]   2.4.99.- [ KEGG ]   
PhosPhoSitePlusQ92186
Domains : Interpro (EBI)Glyco_trans_29    Sialyl_trans   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST8SIA2
DMDM Disease mutations8128
Blocks (Seattle)ST8SIA2
SuperfamilyQ92186
Human Protein AtlasENSG00000140557
Peptide AtlasQ92186
HPRD03969
IPIIPI00020199   IPI00607695   IPI00432722   IPI01026052   
Protein Interaction databases
DIP (DOE-UCLA)Q92186
IntAct (EBI)Q92186
FunCoupENSG00000140557
BioGRIDST8SIA2
STRING (EMBL)ST8SIA2
ZODIACST8SIA2
Ontologies - Pathways
QuickGOQ92186
Ontology : AmiGOGolgi membrane  ganglioside biosynthetic process  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  early endosome  carbohydrate metabolic process  cellular protein modification process  protein glycosylation  protein glycosylation  N-glycan processing  nervous system development  oligosaccharide metabolic process  integral component of Golgi membrane  sialic acid binding  recycling endosome  sialylation  
Ontology : EGO-EBIGolgi membrane  ganglioside biosynthetic process  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  early endosome  carbohydrate metabolic process  cellular protein modification process  protein glycosylation  protein glycosylation  N-glycan processing  nervous system development  oligosaccharide metabolic process  integral component of Golgi membrane  sialic acid binding  recycling endosome  sialylation  
NDEx NetworkST8SIA2
Atlas of Cancer Signalling NetworkST8SIA2
Wikipedia pathwaysST8SIA2
Orthology - Evolution
OrthoDB8128
GeneTree (enSembl)ENSG00000140557
Phylogenetic Trees/Animal Genes : TreeFamST8SIA2
HOVERGENQ92186
HOGENOMQ92186
Homologs : HomoloGeneST8SIA2
Homology/Alignments : Family Browser (UCSC)ST8SIA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST8SIA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST8SIA2
dbVarST8SIA2
ClinVarST8SIA2
1000_GenomesST8SIA2 
Exome Variant ServerST8SIA2
ExAC (Exome Aggregation Consortium)ST8SIA2 (select the gene name)
Genetic variants : HAPMAP8128
Genomic Variants (DGV)ST8SIA2 [DGVbeta]
DECIPHERST8SIA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisST8SIA2 
Mutations
ICGC Data PortalST8SIA2 
TCGA Data PortalST8SIA2 
Broad Tumor PortalST8SIA2
OASIS PortalST8SIA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST8SIA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST8SIA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST8SIA2
DgiDB (Drug Gene Interaction Database)ST8SIA2
DoCM (Curated mutations)ST8SIA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST8SIA2 (select a term)
intoGenST8SIA2
Cancer3DST8SIA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602546   
Orphanet
MedgenST8SIA2
Genetic Testing Registry ST8SIA2
NextProtQ92186 [Medical]
TSGene8128
GENETestsST8SIA2
Target ValidationST8SIA2
Huge Navigator ST8SIA2 [HugePedia]
snp3D : Map Gene to Disease8128
BioCentury BCIQST8SIA2
ClinGenST8SIA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8128
Chemical/Pharm GKB GenePA35771
Clinical trialST8SIA2
Miscellaneous
canSAR (ICR)ST8SIA2 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST8SIA2
EVEXST8SIA2
GoPubMedST8SIA2
iHOPST8SIA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:22 CEST 2017

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