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ST8SIA3 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3)

Identity

Alias_namesSIAT8C
sialyltransferase 8C (alpha2,3Galbeta1,4GlcNAcalpha 2,8-sialyltransferase)
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 3
Other aliasST8SiaIII
HGNC (Hugo) ST8SIA3
LocusID (NCBI) 51046
Atlas_Id 74280
Location 18q21.31  [Link to chromosome band 18q21]
Location_base_pair Starts at 55019721 and ends at 55036161 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ST8SIA3 (18q21.31) / ST8SIA3 (18q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST8SIA3   14269
Cards
Entrez_Gene (NCBI)ST8SIA3  51046  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
AliasesSIAT8C; ST8SiaIII
GeneCards (Weizmann)ST8SIA3
Ensembl hg19 (Hinxton)ENSG00000177511 [Gene_View]  chr18:55019721-55036161 [Contig_View]  ST8SIA3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000177511 [Gene_View]  chr18:55019721-55036161 [Contig_View]  ST8SIA3 [Vega]
ICGC DataPortalENSG00000177511
TCGA cBioPortalST8SIA3
AceView (NCBI)ST8SIA3
Genatlas (Paris)ST8SIA3
WikiGenes51046
SOURCE (Princeton)ST8SIA3
Genetics Home Reference (NIH)ST8SIA3
Genomic and cartography
GoldenPath hg19 (UCSC)ST8SIA3  -     chr18:55019721-55036161 +  18q21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ST8SIA3  -     18q21.31   [Description]    (hg38-Dec_2013)
EnsemblST8SIA3 - 18q21.31 [CytoView hg19]  ST8SIA3 - 18q21.31 [CytoView hg38]
Mapping of homologs : NCBIST8SIA3 [Mapview hg19]  ST8SIA3 [Mapview hg38]
OMIM609478   
Gene and transcription
Genbank (Entrez)AB208996 AF003092 AF004668 AK054939 AK123291
RefSeq transcript (Entrez)NM_015879
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929411
Consensus coding sequences : CCDS (NCBI)ST8SIA3
Cluster EST : UnigeneHs.23172 [ NCBI ]
CGAP (NCI)Hs.23172
Alternative Splicing GalleryENSG00000177511
Gene ExpressionST8SIA3 [ NCBI-GEO ]   ST8SIA3 [ EBI - ARRAY_EXPRESS ]   ST8SIA3 [ SEEK ]   ST8SIA3 [ MEM ]
Gene Expression Viewer (FireBrowse)ST8SIA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51046
GTEX Portal (Tissue expression)ST8SIA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43173   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43173  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43173
Splice isoforms : SwissVarO43173
Catalytic activity : Enzyme2.4.99.- [ Enzyme-Expasy ]   2.4.99.-2.4.99.- [ IntEnz-EBI ]   2.4.99.- [ BRENDA ]   2.4.99.- [ KEGG ]   
PhosPhoSitePlusO43173
Domains : Interpro (EBI)Glyco_trans_29    Sialyl_trans   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST8SIA3
DMDM Disease mutations51046
Blocks (Seattle)ST8SIA3
SuperfamilyO43173
Human Protein AtlasENSG00000177511
Peptide AtlasO43173
HPRD15343
IPIIPI00026285   IPI01009860   
Protein Interaction databases
DIP (DOE-UCLA)O43173
IntAct (EBI)O43173
FunCoupENSG00000177511
BioGRIDST8SIA3
STRING (EMBL)ST8SIA3
ZODIACST8SIA3
Ontologies - Pathways
QuickGOO43173
Ontology : AmiGOGolgi membrane  ganglioside biosynthetic process  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  protein glycosylation  dolichol-linked oligosaccharide biosynthetic process  N-glycan processing  glycosphingolipid biosynthetic process  glycoprotein metabolic process  oligosaccharide metabolic process  protein N-linked glycosylation via asparagine  integral component of Golgi membrane  sialic acid binding  post-translational protein modification  cellular protein metabolic process  sialylation  sialylation  
Ontology : EGO-EBIGolgi membrane  ganglioside biosynthetic process  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  protein glycosylation  dolichol-linked oligosaccharide biosynthetic process  N-glycan processing  glycosphingolipid biosynthetic process  glycoprotein metabolic process  oligosaccharide metabolic process  protein N-linked glycosylation via asparagine  integral component of Golgi membrane  sialic acid binding  post-translational protein modification  cellular protein metabolic process  sialylation  sialylation  
NDEx NetworkST8SIA3
Atlas of Cancer Signalling NetworkST8SIA3
Wikipedia pathwaysST8SIA3
Orthology - Evolution
OrthoDB51046
GeneTree (enSembl)ENSG00000177511
Phylogenetic Trees/Animal Genes : TreeFamST8SIA3
HOVERGENO43173
HOGENOMO43173
Homologs : HomoloGeneST8SIA3
Homology/Alignments : Family Browser (UCSC)ST8SIA3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST8SIA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST8SIA3
dbVarST8SIA3
ClinVarST8SIA3
1000_GenomesST8SIA3 
Exome Variant ServerST8SIA3
ExAC (Exome Aggregation Consortium)ST8SIA3 (select the gene name)
Genetic variants : HAPMAP51046
Genomic Variants (DGV)ST8SIA3 [DGVbeta]
DECIPHER (Syndromes)18:55019721-55036161  ENSG00000177511
CONAN: Copy Number AnalysisST8SIA3 
Mutations
ICGC Data PortalST8SIA3 
TCGA Data PortalST8SIA3 
Broad Tumor PortalST8SIA3
OASIS PortalST8SIA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST8SIA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST8SIA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST8SIA3
DgiDB (Drug Gene Interaction Database)ST8SIA3
DoCM (Curated mutations)ST8SIA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST8SIA3 (select a term)
intoGenST8SIA3
Cancer3DST8SIA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609478   
Orphanet
MedgenST8SIA3
Genetic Testing Registry ST8SIA3
NextProtO43173 [Medical]
TSGene51046
GENETestsST8SIA3
Huge Navigator ST8SIA3 [HugePedia]
snp3D : Map Gene to Disease51046
BioCentury BCIQST8SIA3
ClinGenST8SIA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51046
Chemical/Pharm GKB GenePA37864
Clinical trialST8SIA3
Miscellaneous
canSAR (ICR)ST8SIA3 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST8SIA3
EVEXST8SIA3
GoPubMedST8SIA3
iHOPST8SIA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:46:50 CET 2017

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