ST8SIA5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5)

2014-11-01  

Identity

HGNC
LOCATION
18q21.1
LOCUSID
ALIAS
SIAT8-E,SIAT8E,ST8SiaV
FUSION GENES

Other Information

Locus ID:

NCBI: 29906
MIM: 607162
HGNC: 17827
Ensembl: ENSG00000101638

Variants:

dbSNP: 29906
ClinVar: 29906
TCGA: ENSG00000101638
COSMIC: ST8SIA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101638ENST00000315087O15466
ENSG00000101638ENST00000536490F5H8D1
ENSG00000101638ENST00000538168O15466
ENSG00000101638ENST00000590488K7EN49
ENSG00000101638ENST00000591375K7ER54

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Glycosphingolipid biosynthesis - ganglio seriesKEGGko00604
Glycosphingolipid biosynthesis - ganglio seriesKEGGhsa00604
Metabolic pathwaysKEGGhsa01100
Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3KEGGhsa_M00069
Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3KEGGM00069
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
Sialic acid metabolismREACTOMER-HSA-4085001

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
209309392010Ganglioside metabolism in a transgenic mouse model of Alzheimer's disease: expression of Chol-1α antigens in the brain.16

Citation

Dessen P

ST8SIA5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74281/st8sia5