Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ST8SIA5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5)

Identity

Alias_namesSIAT8E
sialyltransferase 8E (alpha-2, 8-polysialytransferase)
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 5
Other aliasSIAT8-E
ST8SiaV
HGNC (Hugo) ST8SIA5
LocusID (NCBI) 29906
Atlas_Id 74281
Location 18q21.1  [Link to chromosome band 18q21]
Location_base_pair Starts at 46679118 and ends at 46757169 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EPG5 (18q12.3) / ST8SIA5 (18q21.1)ST8SIA5 (18q21.1) / ST8SIA5 (18q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST8SIA5   17827
Cards
Entrez_Gene (NCBI)ST8SIA5  29906  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
AliasesSIAT8-E; SIAT8E; ST8SiaV
GeneCards (Weizmann)ST8SIA5
Ensembl hg19 (Hinxton)ENSG00000101638 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101638 [Gene_View]  chr18:46679118-46757169 [Contig_View]  ST8SIA5 [Vega]
ICGC DataPortalENSG00000101638
TCGA cBioPortalST8SIA5
AceView (NCBI)ST8SIA5
Genatlas (Paris)ST8SIA5
WikiGenes29906
SOURCE (Princeton)ST8SIA5
Genetics Home Reference (NIH)ST8SIA5
Genomic and cartography
GoldenPath hg38 (UCSC)ST8SIA5  -     chr18:46679118-46757169 -  18q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ST8SIA5  -     18q21.1   [Description]    (hg19-Feb_2009)
EnsemblST8SIA5 - 18q21.1 [CytoView hg19]  ST8SIA5 - 18q21.1 [CytoView hg38]
Mapping of homologs : NCBIST8SIA5 [Mapview hg19]  ST8SIA5 [Mapview hg38]
OMIM607162   
Gene and transcription
Genbank (Entrez)AK056270 AK094273 AK130126 AK293608 AK298881
RefSeq transcript (Entrez)NM_001307986 NM_001307987 NM_013305
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ST8SIA5
Cluster EST : UnigeneHs.465025 [ NCBI ]
CGAP (NCI)Hs.465025
Alternative Splicing GalleryENSG00000101638
Gene ExpressionST8SIA5 [ NCBI-GEO ]   ST8SIA5 [ EBI - ARRAY_EXPRESS ]   ST8SIA5 [ SEEK ]   ST8SIA5 [ MEM ]
Gene Expression Viewer (FireBrowse)ST8SIA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29906
GTEX Portal (Tissue expression)ST8SIA5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15466   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15466  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15466
Splice isoforms : SwissVarO15466
Catalytic activity : Enzyme2.4.99.- [ Enzyme-Expasy ]   2.4.99.-2.4.99.- [ IntEnz-EBI ]   2.4.99.- [ BRENDA ]   2.4.99.- [ KEGG ]   
PhosPhoSitePlusO15466
Domains : Interpro (EBI)Glyco_trans_29    Sialyl_trans   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST8SIA5
DMDM Disease mutations29906
Blocks (Seattle)ST8SIA5
SuperfamilyO15466
Human Protein AtlasENSG00000101638
Peptide AtlasO15466
HPRD06199
IPIIPI00289924   IPI00941930   IPI01011481   
Protein Interaction databases
DIP (DOE-UCLA)O15466
IntAct (EBI)O15466
FunCoupENSG00000101638
BioGRIDST8SIA5
STRING (EMBL)ST8SIA5
ZODIACST8SIA5
Ontologies - Pathways
QuickGOO15466
Ontology : AmiGOGolgi membrane  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  protein binding  carbohydrate metabolic process  protein glycosylation  glycosphingolipid biosynthetic process  sialyltransferase activity  integral component of Golgi membrane  sialylation  
Ontology : EGO-EBIGolgi membrane  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  protein binding  carbohydrate metabolic process  protein glycosylation  glycosphingolipid biosynthetic process  sialyltransferase activity  integral component of Golgi membrane  sialylation  
Pathways : KEGGGlycosphingolipid biosynthesis - ganglio series   
NDEx NetworkST8SIA5
Atlas of Cancer Signalling NetworkST8SIA5
Wikipedia pathwaysST8SIA5
Orthology - Evolution
OrthoDB29906
GeneTree (enSembl)ENSG00000101638
Phylogenetic Trees/Animal Genes : TreeFamST8SIA5
HOVERGENO15466
HOGENOMO15466
Homologs : HomoloGeneST8SIA5
Homology/Alignments : Family Browser (UCSC)ST8SIA5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST8SIA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST8SIA5
dbVarST8SIA5
ClinVarST8SIA5
1000_GenomesST8SIA5 
Exome Variant ServerST8SIA5
ExAC (Exome Aggregation Consortium)ST8SIA5 (select the gene name)
Genetic variants : HAPMAP29906
Genomic Variants (DGV)ST8SIA5 [DGVbeta]
DECIPHERST8SIA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisST8SIA5 
Mutations
ICGC Data PortalST8SIA5 
TCGA Data PortalST8SIA5 
Broad Tumor PortalST8SIA5
OASIS PortalST8SIA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST8SIA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST8SIA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST8SIA5
DgiDB (Drug Gene Interaction Database)ST8SIA5
DoCM (Curated mutations)ST8SIA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST8SIA5 (select a term)
intoGenST8SIA5
Cancer3DST8SIA5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607162   
Orphanet
MedgenST8SIA5
Genetic Testing Registry ST8SIA5
NextProtO15466 [Medical]
TSGene29906
GENETestsST8SIA5
Target ValidationST8SIA5
Huge Navigator ST8SIA5 [HugePedia]
snp3D : Map Gene to Disease29906
BioCentury BCIQST8SIA5
ClinGenST8SIA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29906
Chemical/Pharm GKB GenePA38249
Clinical trialST8SIA5
Miscellaneous
canSAR (ICR)ST8SIA5 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST8SIA5
EVEXST8SIA5
GoPubMedST8SIA5
iHOPST8SIA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:44:17 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.