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ST8SIA6 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6)

Identity

Alias_namesSIAT8F
sialyltransferase 8F (alpha-2, 8-sialyltransferase)
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 6
Other aliasSIA8F
ST8SIA-VI
HGNC (Hugo) ST8SIA6
LocusID (NCBI) 338596
Atlas_Id 55749
Location 10p12.33  [Link to chromosome band 10p12]
Location_base_pair Starts at 17362676 and ends at 17496254 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PLXDC2 (10p12.31) / ST8SIA6 (10p12.33)ST8SIA6 (10p12.33) / ST8SIA6 (10p12.33)ST8SIA6 (10p12.33) / TAF15 (17q12)
TNFSF9 (19p13.3) / ST8SIA6 (10p12.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ST8SIA6   23317
Cards
Entrez_Gene (NCBI)ST8SIA6  338596  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
AliasesSIA8F; SIAT8F; ST8SIA-VI
GeneCards (Weizmann)ST8SIA6
Ensembl hg19 (Hinxton)ENSG00000148488 [Gene_View]  chr10:17362676-17496254 [Contig_View]  ST8SIA6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000148488 [Gene_View]  chr10:17362676-17496254 [Contig_View]  ST8SIA6 [Vega]
ICGC DataPortalENSG00000148488
TCGA cBioPortalST8SIA6
AceView (NCBI)ST8SIA6
Genatlas (Paris)ST8SIA6
WikiGenes338596
SOURCE (Princeton)ST8SIA6
Genetics Home Reference (NIH)ST8SIA6
Genomic and cartography
GoldenPath hg19 (UCSC)ST8SIA6  -     chr10:17362676-17496254 -  10p12.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ST8SIA6  -     10p12.33   [Description]    (hg38-Dec_2013)
EnsemblST8SIA6 - 10p12.33 [CytoView hg19]  ST8SIA6 - 10p12.33 [CytoView hg38]
Mapping of homologs : NCBIST8SIA6 [Mapview hg19]  ST8SIA6 [Mapview hg38]
OMIM610139   
Gene and transcription
Genbank (Entrez)AB062101 AJ621583 BC137102 BC137103 BC144472
RefSeq transcript (Entrez)NM_001004470
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_008705 NW_004929370
Consensus coding sequences : CCDS (NCBI)ST8SIA6
Cluster EST : UnigeneHs.677766 [ NCBI ]
CGAP (NCI)Hs.677766
Alternative Splicing GalleryENSG00000148488
Gene ExpressionST8SIA6 [ NCBI-GEO ]   ST8SIA6 [ EBI - ARRAY_EXPRESS ]   ST8SIA6 [ SEEK ]   ST8SIA6 [ MEM ]
Gene Expression Viewer (FireBrowse)ST8SIA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)338596
GTEX Portal (Tissue expression)ST8SIA6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61647   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61647  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61647
Splice isoforms : SwissVarP61647
Catalytic activity : Enzyme2.4.99.- [ Enzyme-Expasy ]   2.4.99.-2.4.99.- [ IntEnz-EBI ]   2.4.99.- [ BRENDA ]   2.4.99.- [ KEGG ]   
PhosPhoSitePlusP61647
Domains : Interpro (EBI)Glyco_trans_29    Sialyl_trans   
Domain families : Pfam (Sanger)Glyco_transf_29 (PF00777)   
Domain families : Pfam (NCBI)pfam00777   
Conserved Domain (NCBI)ST8SIA6
DMDM Disease mutations338596
Blocks (Seattle)ST8SIA6
SuperfamilyP61647
Human Protein AtlasENSG00000148488
Peptide AtlasP61647
HPRD15344
IPIIPI00259856   IPI00552133   
Protein Interaction databases
DIP (DOE-UCLA)P61647
IntAct (EBI)P61647
FunCoupENSG00000148488
BioGRIDST8SIA6
STRING (EMBL)ST8SIA6
ZODIACST8SIA6
Ontologies - Pathways
QuickGOP61647
Ontology : AmiGOGolgi membrane  ganglioside biosynthetic process  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  protein O-linked glycosylation  sialyltransferase activity  glycoprotein metabolic process  glycolipid biosynthetic process  oligosaccharide metabolic process  carbohydrate biosynthetic process  integral component of Golgi membrane  sialylation  
Ontology : EGO-EBIGolgi membrane  ganglioside biosynthetic process  alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity  protein O-linked glycosylation  sialyltransferase activity  glycoprotein metabolic process  glycolipid biosynthetic process  oligosaccharide metabolic process  carbohydrate biosynthetic process  integral component of Golgi membrane  sialylation  
NDEx NetworkST8SIA6
Atlas of Cancer Signalling NetworkST8SIA6
Wikipedia pathwaysST8SIA6
Orthology - Evolution
OrthoDB338596
GeneTree (enSembl)ENSG00000148488
Phylogenetic Trees/Animal Genes : TreeFamST8SIA6
HOVERGENP61647
HOGENOMP61647
Homologs : HomoloGeneST8SIA6
Homology/Alignments : Family Browser (UCSC)ST8SIA6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerST8SIA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ST8SIA6
dbVarST8SIA6
ClinVarST8SIA6
1000_GenomesST8SIA6 
Exome Variant ServerST8SIA6
ExAC (Exome Aggregation Consortium)ST8SIA6 (select the gene name)
Genetic variants : HAPMAP338596
Genomic Variants (DGV)ST8SIA6 [DGVbeta]
DECIPHER (Syndromes)10:17362676-17496254  ENSG00000148488
CONAN: Copy Number AnalysisST8SIA6 
Mutations
ICGC Data PortalST8SIA6 
TCGA Data PortalST8SIA6 
Broad Tumor PortalST8SIA6
OASIS PortalST8SIA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICST8SIA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDST8SIA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ST8SIA6
DgiDB (Drug Gene Interaction Database)ST8SIA6
DoCM (Curated mutations)ST8SIA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ST8SIA6 (select a term)
intoGenST8SIA6
Cancer3DST8SIA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610139   
Orphanet
MedgenST8SIA6
Genetic Testing Registry ST8SIA6
NextProtP61647 [Medical]
TSGene338596
GENETestsST8SIA6
Huge Navigator ST8SIA6 [HugePedia]
snp3D : Map Gene to Disease338596
BioCentury BCIQST8SIA6
ClinGenST8SIA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD338596
Chemical/Pharm GKB GenePA134909138
Clinical trialST8SIA6
Miscellaneous
canSAR (ICR)ST8SIA6 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineST8SIA6
EVEXST8SIA6
GoPubMedST8SIA6
iHOPST8SIA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:29:31 CET 2017

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