STAB1 (stabilin 1)

2011-06-01  

Identity

HGNC
LOCATION
3p21.1
LOCUSID
ALIAS
CLEVER-1,FEEL-1,FELE-1,FEX1,SCARH2,STAB-1
FUSION GENES

Other Information

Locus ID:

NCBI: 23166
MIM: 608560
HGNC: 18628
Ensembl: ENSG00000010327

Variants:

dbSNP: 23166
ClinVar: 23166
TCGA: ENSG00000010327
COSMIC: STAB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000010327ENST00000321725Q9NY15
ENSG00000010327ENST00000469989H7C4W7

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging by Class H ReceptorsREACTOMER-HSA-3000497

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
209356292010Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.396
118297522002Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.75
166702882006Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC.58
170069782006Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo.54
197266322009Stabilin-1 mediates phosphatidylserine-dependent clearance of cell corpses in alternatively activated macrophages.52
124736452003FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.44
213682242011Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells across human hepatic sinusoidal endothelium.43
120771382002FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.42
152973192004CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium.34
209535542010Multifunctional receptor stabilin-1 in homeostasis and disease.27

Citation

Dessen P

STAB1 (stabilin 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52235/stab1