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STAB2 (stabilin 2)

Identity

Alias_symbol (synonym)DKFZP434E0321
FELL
STAB-2
HARE
FEEL-2
SCARH1
Other aliasFEEL2
FELE-2
FELL2
FEX2
HGNC (Hugo) STAB2
LocusID (NCBI) 55576
Atlas_Id 53867
Location 12q23.3  [Link to chromosome band 12q23]
Location_base_pair Starts at 103587291 and ends at 103766724 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DPYD (1p21.3) / STAB2 (12q23.3)NOC4L (12q24.33) / STAB2 (12q23.3)TDG (12q23.3) / STAB2 (12q23.3)
DPYD 1p21.3 / STAB2 12q23.3NOC4L 12q24.33 / STAB2 12q23.3TDG 12q23.3 / STAB2 12q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STAB2   18629
Cards
Entrez_Gene (NCBI)STAB2  55576  stabilin 2
AliasesFEEL2; FELE-2; FELL2; FEX2; 
HARE; SCARH1
GeneCards (Weizmann)STAB2
Ensembl hg19 (Hinxton)ENSG00000136011 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136011 [Gene_View]  chr12:103587291-103766724 [Contig_View]  STAB2 [Vega]
ICGC DataPortalENSG00000136011
TCGA cBioPortalSTAB2
AceView (NCBI)STAB2
Genatlas (Paris)STAB2
WikiGenes55576
SOURCE (Princeton)STAB2
Genetics Home Reference (NIH)STAB2
Genomic and cartography
GoldenPath hg38 (UCSC)STAB2  -     chr12:103587291-103766724 +  12q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STAB2  -     12q23.3   [Description]    (hg19-Feb_2009)
EnsemblSTAB2 - 12q23.3 [CytoView hg19]  STAB2 - 12q23.3 [CytoView hg38]
Mapping of homologs : NCBISTAB2 [Mapview hg19]  STAB2 [Mapview hg38]
OMIM608561   
Gene and transcription
Genbank (Entrez)AB052958 AF160476 AJ295695 AK024503 AK074051
RefSeq transcript (Entrez)NM_017564
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STAB2
Cluster EST : UnigeneHs.408249 [ NCBI ]
CGAP (NCI)Hs.408249
Alternative Splicing GalleryENSG00000136011
Gene ExpressionSTAB2 [ NCBI-GEO ]   STAB2 [ EBI - ARRAY_EXPRESS ]   STAB2 [ SEEK ]   STAB2 [ MEM ]
Gene Expression Viewer (FireBrowse)STAB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55576
GTEX Portal (Tissue expression)STAB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWQ8
Splice isoforms : SwissVarQ8WWQ8
PhosPhoSitePlusQ8WWQ8
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_LAM_1 (PS01248)    FAS1 (PS50213)    LINK_1 (PS01241)    LINK_2 (PS50963)   
Domains : Interpro (EBI)C-type_lectin-like/link    CTDL_fold    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF_dom    FAS1_domain    GFP-like    Laminin_EGF    Link_dom   
Domain families : Pfam (Sanger)EGF_3 (PF12947)    Fasciclin (PF02469)    Xlink (PF00193)   
Domain families : Pfam (NCBI)pfam12947    pfam02469    pfam00193   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  EGF_Lam (SM00180)  FAS1 (SM00554)  LINK (SM00445)  
Conserved Domain (NCBI)STAB2
DMDM Disease mutations55576
Blocks (Seattle)STAB2
SuperfamilyQ8WWQ8
Human Protein AtlasENSG00000136011
Peptide AtlasQ8WWQ8
HPRD10542
IPIIPI00292579   IPI00784394   IPI01022391   IPI01021967   
Protein Interaction databases
DIP (DOE-UCLA)Q8WWQ8
IntAct (EBI)Q8WWQ8
FunCoupENSG00000136011
BioGRIDSTAB2
STRING (EMBL)STAB2
ZODIACSTAB2
Ontologies - Pathways
QuickGOQ8WWQ8
Ontology : AmiGOangiogenesis  low-density lipoprotein receptor activity  scavenger receptor activity  calcium ion binding  protein binding  hyaluronic acid binding  cytosol  plasma membrane  integral component of plasma membrane  endocytosis  receptor-mediated endocytosis  cell adhesion  external side of plasma membrane  regulation of gene expression  protein disulfide oxidoreductase activity  low-density lipoprotein particle binding  regulation of blood coagulation  hyaluronan catabolic process  endocytic vesicle membrane  defense response to bacterium  oxidation-reduction process  
Ontology : EGO-EBIangiogenesis  low-density lipoprotein receptor activity  scavenger receptor activity  calcium ion binding  protein binding  hyaluronic acid binding  cytosol  plasma membrane  integral component of plasma membrane  endocytosis  receptor-mediated endocytosis  cell adhesion  external side of plasma membrane  regulation of gene expression  protein disulfide oxidoreductase activity  low-density lipoprotein particle binding  regulation of blood coagulation  hyaluronan catabolic process  endocytic vesicle membrane  defense response to bacterium  oxidation-reduction process  
NDEx NetworkSTAB2
Atlas of Cancer Signalling NetworkSTAB2
Wikipedia pathwaysSTAB2
Orthology - Evolution
OrthoDB55576
GeneTree (enSembl)ENSG00000136011
Phylogenetic Trees/Animal Genes : TreeFamSTAB2
HOVERGENQ8WWQ8
HOGENOMQ8WWQ8
Homologs : HomoloGeneSTAB2
Homology/Alignments : Family Browser (UCSC)STAB2
Gene fusions - Rearrangements
Fusion : MitelmanDPYD/STAB2 [1p21.3/12q23.3]  [t(1;12)(p21;q23)]  
Fusion : MitelmanNOC4L/STAB2 [12q24.33/12q23.3]  [t(12;12)(q23;q24)]  
Fusion : MitelmanTDG/STAB2 [12q23.3/12q23.3]  [t(12;12)(q23;q23)]  
Fusion: TCGADPYD 1p21.3 STAB2 12q23.3 BRCA
Fusion: TCGANOC4L 12q24.33 STAB2 12q23.3 LUSC
Fusion: TCGATDG 12q23.3 STAB2 12q23.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAB2
dbVarSTAB2
ClinVarSTAB2
1000_GenomesSTAB2 
Exome Variant ServerSTAB2
ExAC (Exome Aggregation Consortium)STAB2 (select the gene name)
Genetic variants : HAPMAP55576
Genomic Variants (DGV)STAB2 [DGVbeta]
DECIPHERSTAB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTAB2 
Mutations
ICGC Data PortalSTAB2 
TCGA Data PortalSTAB2 
Broad Tumor PortalSTAB2
OASIS PortalSTAB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTAB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTAB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STAB2
DgiDB (Drug Gene Interaction Database)STAB2
DoCM (Curated mutations)STAB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STAB2 (select a term)
intoGenSTAB2
Cancer3DSTAB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608561   
Orphanet
MedgenSTAB2
Genetic Testing Registry STAB2
NextProtQ8WWQ8 [Medical]
TSGene55576
GENETestsSTAB2
Target ValidationSTAB2
Huge Navigator STAB2 [HugePedia]
snp3D : Map Gene to Disease55576
BioCentury BCIQSTAB2
ClinGenSTAB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55576
Chemical/Pharm GKB GenePA38611
Clinical trialSTAB2
Miscellaneous
canSAR (ICR)STAB2 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTAB2
EVEXSTAB2
GoPubMedSTAB2
iHOPSTAB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:22 CEST 2017

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