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STAC3 (SH3 and cysteine rich domain 3)

Identity

Alias (NCBI)MYPBB
NAM
HGNC (Hugo) STAC3
HGNC Alias symbMGC2793
LocusID (NCBI) 246329
Atlas_Id 58386
Location 12q13.3  [Link to chromosome band 12q13]
Location_base_pair Starts at 57243458 and ends at 57251187 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)STAC3   28423
Cards
Entrez_Gene (NCBI)STAC3    SH3 and cysteine rich domain 3
AliasesMYPBB; NAM
GeneCards (Weizmann)STAC3
Ensembl hg19 (Hinxton)ENSG00000185482 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185482 [Gene_View]  ENSG00000185482 [Sequence]  chr12:57243458-57251187 [Contig_View]  STAC3 [Vega]
ICGC DataPortalENSG00000185482
TCGA cBioPortalSTAC3
AceView (NCBI)STAC3
Genatlas (Paris)STAC3
SOURCE (Princeton)STAC3
Genetics Home Reference (NIH)STAC3
Genomic and cartography
GoldenPath hg38 (UCSC)STAC3  -     chr12:57243458-57251187 -  12q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STAC3  -     12q13.3   [Description]    (hg19-Feb_2009)
GoldenPathSTAC3 - 12q13.3 [CytoView hg19]  STAC3 - 12q13.3 [CytoView hg38]
ImmunoBaseENSG00000185482
Genome Data Viewer NCBISTAC3 [Mapview hg19]  
OMIM255995   615521   
Gene and transcription
Genbank (Entrez)AK057013 AK300688 AK311513 BC008069 BU738507
RefSeq transcript (Entrez)NM_001286256 NM_001286257 NM_145064
Consensus coding sequences : CCDS (NCBI)STAC3
Gene ExpressionSTAC3 [ NCBI-GEO ]   STAC3 [ EBI - ARRAY_EXPRESS ]   STAC3 [ SEEK ]   STAC3 [ MEM ]
Gene Expression Viewer (FireBrowse)STAC3 [ Firebrowse - Broad ]
GenevisibleExpression of STAC3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246329
GTEX Portal (Tissue expression)STAC3
Human Protein AtlasENSG00000185482-STAC3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MF2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MF2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MF2
PhosPhoSitePlusQ96MF2
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)PE/DAG-bd    SH3-like_dom_sf    SH3_domain    STAC1/2/3    Stac3_SH3_1   
Domain families : Pfam (Sanger)C1_1 (PF00130)    SH3_1 (PF00018)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam00130    pfam00018    pfam07653   
Domain families : Smart (EMBL)C1 (SM00109)  SH3 (SM00326)  
Conserved Domain (NCBI)STAC3
PDB (RSDB)2DB6    6B29    6UY7    6UY8    6UY9   
PDB Europe2DB6    6B29    6UY7    6UY8    6UY9   
PDB (PDBSum)2DB6    6B29    6UY7    6UY8    6UY9   
PDB (IMB)2DB6    6B29    6UY7    6UY8    6UY9   
Structural Biology KnowledgeBase2DB6    6B29    6UY7    6UY8    6UY9   
SCOP (Structural Classification of Proteins)2DB6    6B29    6UY7    6UY8    6UY9   
CATH (Classification of proteins structures)2DB6    6B29    6UY7    6UY8    6UY9   
SuperfamilyQ96MF2
AlphaFold pdb e-kbQ96MF2   
Human Protein Atlas [tissue]ENSG00000185482-STAC3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q96MF2
IntAct (EBI)Q96MF2
BioGRIDSTAC3
STRING (EMBL)STAC3
ZODIACSTAC3
Ontologies - Pathways
QuickGOQ96MF2
Ontology : AmiGOskeletal muscle contraction  skeletal muscle contraction  protein binding  nucleoplasm  cytosol  voltage-gated calcium channel complex  neuromuscular synaptic transmission  T-tubule  extrinsic component of cytoplasmic side of plasma membrane  extrinsic component of cytoplasmic side of plasma membrane  intracellular signal transduction  identical protein binding  synapse  metal ion binding  skeletal muscle fiber development  positive regulation of voltage-gated calcium channel activity  positive regulation of voltage-gated calcium channel activity  positive regulation of protein localization to plasma membrane  positive regulation of protein localization to plasma membrane  
Ontology : EGO-EBIskeletal muscle contraction  skeletal muscle contraction  protein binding  nucleoplasm  cytosol  voltage-gated calcium channel complex  neuromuscular synaptic transmission  T-tubule  extrinsic component of cytoplasmic side of plasma membrane  extrinsic component of cytoplasmic side of plasma membrane  intracellular signal transduction  identical protein binding  synapse  metal ion binding  skeletal muscle fiber development  positive regulation of voltage-gated calcium channel activity  positive regulation of voltage-gated calcium channel activity  positive regulation of protein localization to plasma membrane  positive regulation of protein localization to plasma membrane  
NDEx NetworkSTAC3
Atlas of Cancer Signalling NetworkSTAC3
Wikipedia pathwaysSTAC3
Orthology - Evolution
OrthoDB246329
GeneTree (enSembl)ENSG00000185482
Phylogenetic Trees/Animal Genes : TreeFamSTAC3
Homologs : HomoloGeneSTAC3
Homology/Alignments : Family Browser (UCSC)STAC3
Gene fusions - Rearrangements
Fusion : QuiverSTAC3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAC3
dbVarSTAC3
ClinVarSTAC3
MonarchSTAC3
1000_GenomesSTAC3 
Exome Variant ServerSTAC3
GNOMAD BrowserENSG00000185482
Varsome BrowserSTAC3
ACMGSTAC3 variants
VarityQ96MF2
Genomic Variants (DGV)STAC3 [DGVbeta]
DECIPHERSTAC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTAC3 
Mutations
ICGC Data PortalSTAC3 
TCGA Data PortalSTAC3 
Broad Tumor PortalSTAC3
OASIS PortalSTAC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTAC3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTAC3
Mutations and Diseases : HGMDSTAC3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTAC3
DgiDB (Drug Gene Interaction Database)STAC3
DoCM (Curated mutations)STAC3
CIViC (Clinical Interpretations of Variants in Cancer)STAC3
Cancer3DSTAC3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM255995    615521   
Orphanet
DisGeNETSTAC3
MedgenSTAC3
Genetic Testing Registry STAC3
NextProtQ96MF2 [Medical]
GENETestsSTAC3
Target ValidationSTAC3
Huge Navigator STAC3 [HugePedia]
ClinGenSTAC3
Clinical trials, drugs, therapy
MyCancerGenomeSTAC3
Protein Interactions : CTDSTAC3
PharosQ96MF2
Clinical trialSTAC3
Miscellaneous
canSAR (ICR)STAC3
HarmonizomeSTAC3
DataMed IndexSTAC3
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTAC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:33:29 CEST 2021

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