Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

STAG1 (stromal antigen 1)

Identity

Alias_symbol (synonym)SA-1
SCC3A
SA1
Other alias
HGNC (Hugo) STAG1
LocusID (NCBI) 10274
Atlas_Id 45894
Location 3q22.3  [Link to chromosome band 3q22]
Location_base_pair Starts at 136337157 and ends at 136752403 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP70 (3q22.3) / STAG1 (3q22.3)LSAMP (3q13.31) / STAG1 (3q22.3)MSL2 (3q22.3) / STAG1 (3q22.3)
RNF43 (17q22) / STAG1 (3q22.3)STAG1 (3q22.3) / CCDC77 (12p13.33)STAG1 (3q22.3) / HRH1 (3p25.3)
STAG1 (3q22.3) / ISY1 (3q21.3)STAG1 (3q22.3) / MSL2 (3q22.3)STAG1 (3q22.3) / STAG1 (3q22.3)
STAG1 (3q22.3) / STXBP5L (3q13.33)STXBP5L (3q13.33) / STAG1 (3q22.3)CEP70 3q22.3 / STAG1 3q22.3
MSL2 3q22.3 / STAG1 3q22.3STAG1 3q22.3 / CCDC77 12p13.33STAG1 3q22.3 / ISY1 3q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Chronic Myelomonocytic Leukemia (CMML)


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)STAG1   11354
Cards
Entrez_Gene (NCBI)STAG1  10274  stromal antigen 1
AliasesSA1; SCC3A
GeneCards (Weizmann)STAG1
Ensembl hg19 (Hinxton)ENSG00000118007 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118007 [Gene_View]  chr3:136337157-136752403 [Contig_View]  STAG1 [Vega]
ICGC DataPortalENSG00000118007
TCGA cBioPortalSTAG1
AceView (NCBI)STAG1
Genatlas (Paris)STAG1
WikiGenes10274
SOURCE (Princeton)STAG1
Genetics Home Reference (NIH)STAG1
Genomic and cartography
GoldenPath hg38 (UCSC)STAG1  -     chr3:136337157-136752403 -  3q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STAG1  -     3q22.3   [Description]    (hg19-Feb_2009)
EnsemblSTAG1 - 3q22.3 [CytoView hg19]  STAG1 - 3q22.3 [CytoView hg38]
Mapping of homologs : NCBISTAG1 [Mapview hg19]  STAG1 [Mapview hg38]
OMIM604358   
Gene and transcription
Genbank (Entrez)AB210023 AK124202 AK304381 AK309934 AU132652
RefSeq transcript (Entrez)NM_005862
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STAG1
Cluster EST : UnigeneHs.412586 [ NCBI ]
CGAP (NCI)Hs.412586
Alternative Splicing GalleryENSG00000118007
Gene ExpressionSTAG1 [ NCBI-GEO ]   STAG1 [ EBI - ARRAY_EXPRESS ]   STAG1 [ SEEK ]   STAG1 [ MEM ]
Gene Expression Viewer (FireBrowse)STAG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10274
GTEX Portal (Tissue expression)STAG1
Human Protein AtlasENSG00000118007-STAG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVM7
Splice isoforms : SwissVarQ8WVM7
PhosPhoSitePlusQ8WVM7
Domaine pattern : Prosite (Expaxy)SCD (PS51425)   
Domains : Interpro (EBI)ARM-type_fold    SCD    STAG   
Domain families : Pfam (Sanger)STAG (PF08514)   
Domain families : Pfam (NCBI)pfam08514   
Conserved Domain (NCBI)STAG1
DMDM Disease mutations10274
Blocks (Seattle)STAG1
SuperfamilyQ8WVM7
Human Protein Atlas [tissue]ENSG00000118007-STAG1 [tissue]
Peptide AtlasQ8WVM7
HPRD05076
IPIIPI00025158   IPI01015989   IPI01013789   IPI00619944   IPI00978766   IPI00945256   IPI00947236   IPI00945370   
Protein Interaction databases
DIP (DOE-UCLA)Q8WVM7
IntAct (EBI)Q8WVM7
FunCoupENSG00000118007
BioGRIDSTAG1
STRING (EMBL)STAG1
ZODIACSTAG1
Ontologies - Pathways
QuickGOQ8WVM7
Ontology : AmiGOchromosome, centromeric region  chromatin  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  chromatin binding  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  transcription from RNA polymerase II promoter  sister chromatid cohesion  nuclear body  positive regulation of transcription from RNA polymerase II promoter  cell division  
Ontology : EGO-EBIchromosome, centromeric region  chromatin  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  chromatin binding  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  transcription from RNA polymerase II promoter  sister chromatid cohesion  nuclear body  positive regulation of transcription from RNA polymerase II promoter  cell division  
Pathways : KEGGCell cycle   
NDEx NetworkSTAG1
Atlas of Cancer Signalling NetworkSTAG1
Wikipedia pathwaysSTAG1
Orthology - Evolution
OrthoDB10274
GeneTree (enSembl)ENSG00000118007
Phylogenetic Trees/Animal Genes : TreeFamSTAG1
HOVERGENQ8WVM7
HOGENOMQ8WVM7
Homologs : HomoloGeneSTAG1
Homology/Alignments : Family Browser (UCSC)STAG1
Gene fusions - Rearrangements
Fusion : MitelmanCEP70/STAG1 [3q22.3/3q22.3]  [t(3;3)(q22;q22)]  
Fusion : MitelmanLSAMP/STAG1 [3q13.31/3q22.3]  [t(3;3)(q13;q22)]  
Fusion : MitelmanMSL2/STAG1 [3q22.3/3q22.3]  [t(3;3)(q22;q22)]  
Fusion : MitelmanSTAG1/CCDC77 [3q22.3/12p13.33]  [t(3;12)(q22;p13)]  
Fusion : MitelmanSTAG1/ISY1 [3q22.3/3q21.3]  [t(3;3)(q21;q22)]  
Fusion : MitelmanSTAG1/MSL2 [3q22.3/3q22.3]  [t(3;3)(q22;q22)]  
Fusion : MitelmanSTAG1/STXBP5L [3q22.3/3q13.33]  [t(3;3)(q13;q22)]  
Fusion: TCGA_MDACCCEP70 3q22.3 STAG1 3q22.3 BRCA
Fusion: TCGA_MDACCMSL2 3q22.3 STAG1 3q22.3 BRCA OV
Fusion: TCGA_MDACCSTAG1 3q22.3 CCDC77 12p13.33 BRCA
Fusion: TCGA_MDACCSTAG1 3q22.3 ISY1 3q21.3 BRCA
Tumor Fusion PortalSTAG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAG1
dbVarSTAG1
ClinVarSTAG1
1000_GenomesSTAG1 
Exome Variant ServerSTAG1
ExAC (Exome Aggregation Consortium)ENSG00000118007
GNOMAD BrowserENSG00000118007
Genetic variants : HAPMAP10274
Genomic Variants (DGV)STAG1 [DGVbeta]
DECIPHERSTAG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTAG1 
Mutations
ICGC Data PortalSTAG1 
TCGA Data PortalSTAG1 
Broad Tumor PortalSTAG1
OASIS PortalSTAG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTAG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTAG1
intOGen PortalSTAG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STAG1
DgiDB (Drug Gene Interaction Database)STAG1
DoCM (Curated mutations)STAG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STAG1 (select a term)
intoGenSTAG1
Cancer3DSTAG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604358   
Orphanet
DisGeNETSTAG1
MedgenSTAG1
Genetic Testing Registry STAG1
NextProtQ8WVM7 [Medical]
TSGene10274
GENETestsSTAG1
Target ValidationSTAG1
Huge Navigator STAG1 [HugePedia]
snp3D : Map Gene to Disease10274
BioCentury BCIQSTAG1
ClinGenSTAG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10274
Chemical/Pharm GKB GenePA36176
Clinical trialSTAG1
Miscellaneous
canSAR (ICR)STAG1 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTAG1
EVEXSTAG1
GoPubMedSTAG1
iHOPSTAG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:36:53 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.