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STAG1 (stromal antigen 1)

Identity

Alias (NCBI)MRD47
SA1
SCC3A
HGNC (Hugo) STAG1
HGNC Alias symbSA-1
SCC3A
SA1
HGNC Alias namecohesin subunit SA-1
LocusID (NCBI) 10274
Atlas_Id 45894
Location 3q22.3  [Link to chromosome band 3q22]
Location_base_pair Starts at 136336236 and ends at 136752378 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP70 (3q22.3)::STAG1 (3q22.3)LSAMP (3q13.31)::STAG1 (3q22.3)MSL2 (3q22.3)::STAG1 (3q22.3)
RNF43 (17q22)::STAG1 (3q22.3)STAG1 (3q22.3)::CCDC77 (12p13.33)STAG1 (3q22.3)::HRH1 (3p25.3)
STAG1 (3q22.3)::ISY1 (3q21.3)STAG1 (3q22.3)::MSL2 (3q22.3)STAG1 (3q22.3)::STAG1 (3q22.3)
STAG1 (3q22.3)::STXBP5L (3q13.33)STXBP5L (3q13.33)::STAG1 (3q22.3)CEP70 3q22.3::STAG1 3q22.3
MSL2 3q22.3::STAG1 3q22.3STAG1 3q22.3::CCDC77 12p13.33STAG1 3q22.3::ISY1 3q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Chronic Myelomonocytic Leukemia (CMML)


External links

 

Nomenclature
HGNC (Hugo)STAG1   11354
Cards
Entrez_Gene (NCBI)STAG1    stromal antigen 1
AliasesMRD47; SA1; SCC3A
GeneCards (Weizmann)STAG1
Ensembl hg19 (Hinxton)ENSG00000118007 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118007 [Gene_View]  ENSG00000118007 [Sequence]  chr3:136336236-136752378 [Contig_View]  STAG1 [Vega]
ICGC DataPortalENSG00000118007
TCGA cBioPortalSTAG1
AceView (NCBI)STAG1
Genatlas (Paris)STAG1
SOURCE (Princeton)STAG1
Genetics Home Reference (NIH)STAG1
Genomic and cartography
GoldenPath hg38 (UCSC)STAG1  -     chr3:136336236-136752378 -  3q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STAG1  -     3q22.3   [Description]    (hg19-Feb_2009)
GoldenPathSTAG1 - 3q22.3 [CytoView hg19]  STAG1 - 3q22.3 [CytoView hg38]
ImmunoBaseENSG00000118007
Genome Data Viewer NCBISTAG1 [Mapview hg19]  
OMIM604358   617635   
Gene and transcription
Genbank (Entrez)AB210023 AK124202 AK304381 AK309934 AU132652
RefSeq transcript (Entrez)NM_005862
Consensus coding sequences : CCDS (NCBI)STAG1
Gene ExpressionSTAG1 [ NCBI-GEO ]   STAG1 [ EBI - ARRAY_EXPRESS ]   STAG1 [ SEEK ]   STAG1 [ MEM ]
Gene Expression Viewer (FireBrowse)STAG1 [ Firebrowse - Broad ]
GenevisibleExpression of STAG1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10274
GTEX Portal (Tissue expression)STAG1
Human Protein AtlasENSG00000118007-STAG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVM7
PhosPhoSitePlusQ8WVM7
Domaine pattern : Prosite (Expaxy)SCD (PS51425)   
Domains : Interpro (EBI)ARM-type_fold    Cohesin_Scc3/SA    SCD    STAG   
Domain families : Pfam (Sanger)STAG (PF08514)   
Domain families : Pfam (NCBI)pfam08514   
Conserved Domain (NCBI)STAG1
PDB (RSDB)5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
PDB Europe5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
PDB (PDBSum)5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
PDB (IMB)5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
Structural Biology KnowledgeBase5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
SCOP (Structural Classification of Proteins)5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
CATH (Classification of proteins structures)5QSM    5QSN    5QSO    5QSP    5QSQ    5QSR    5QSS    5QST    5QSU    5QSV    5QSW    5QSX    5QSY    5QSZ    6QB5    6R7O    6RRC    6RRK    6WG3   
SuperfamilyQ8WVM7
AlphaFold pdb e-kbQ8WVM7   
Human Protein Atlas [tissue]ENSG00000118007-STAG1 [tissue]
HPRD05076
Protein Interaction databases
DIP (DOE-UCLA)Q8WVM7
IntAct (EBI)Q8WVM7
BioGRIDSTAG1
STRING (EMBL)STAG1
ZODIACSTAG1
Ontologies - Pathways
QuickGOQ8WVM7
Ontology : AmiGOchromosome, centromeric region  chromatin  chromatin  chromatin binding  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  sister chromatid cohesion  cohesin complex  cohesin complex  nuclear matrix  nuclear body  cell division  mitotic spindle assembly  mitotic spindle pole  
Ontology : EGO-EBIchromosome, centromeric region  chromatin  chromatin  chromatin binding  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  sister chromatid cohesion  cohesin complex  cohesin complex  nuclear matrix  nuclear body  cell division  mitotic spindle assembly  mitotic spindle pole  
Pathways : KEGGKEGG_CELL_CYCLE   
NDEx NetworkSTAG1
Atlas of Cancer Signalling NetworkSTAG1
Wikipedia pathwaysSTAG1
Orthology - Evolution
OrthoDB10274
GeneTree (enSembl)ENSG00000118007
Phylogenetic Trees/Animal Genes : TreeFamSTAG1
Homologs : HomoloGeneSTAG1
Homology/Alignments : Family Browser (UCSC)STAG1
Gene fusions - Rearrangements
Fusion : MitelmanCEP70::STAG1 [3q22.3/3q22.3]  
Fusion : MitelmanLSAMP::STAG1 [3q13.31/3q22.3]  
Fusion : MitelmanMSL2::STAG1 [3q22.3/3q22.3]  
Fusion : MitelmanSTAG1::CCDC77 [3q22.3/12p13.33]  
Fusion : MitelmanSTAG1::ISY1 [3q22.3/3q21.3]  
Fusion : MitelmanSTAG1::MSL2 [3q22.3/3q22.3]  
Fusion : MitelmanSTAG1::STXBP5L [3q22.3/3q13.33]  
Fusion : QuiverSTAG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAG1
dbVarSTAG1
ClinVarSTAG1
MonarchSTAG1
1000_GenomesSTAG1 
Exome Variant ServerSTAG1
GNOMAD BrowserENSG00000118007
Varsome BrowserSTAG1
ACMGSTAG1 variants
VarityQ8WVM7
Genomic Variants (DGV)STAG1 [DGVbeta]
DECIPHERSTAG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTAG1 
Mutations
ICGC Data PortalSTAG1 
TCGA Data PortalSTAG1 
Broad Tumor PortalSTAG1
OASIS PortalSTAG1 [ Somatic mutations - Copy number]
Cancer Gene: CensusSTAG1 
Somatic Mutations in Cancer : COSMICSTAG1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTAG1
Mutations and Diseases : HGMDSTAG1
intOGen PortalSTAG1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTAG1
DgiDB (Drug Gene Interaction Database)STAG1
DoCM (Curated mutations)STAG1
CIViC (Clinical Interpretations of Variants in Cancer)STAG1
Cancer3DSTAG1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604358    617635   
Orphanet26078   
DisGeNETSTAG1
MedgenSTAG1
Genetic Testing Registry STAG1
NextProtQ8WVM7 [Medical]
GENETestsSTAG1
Target ValidationSTAG1
Huge Navigator STAG1 [HugePedia]
ClinGenSTAG1
Clinical trials, drugs, therapy
MyCancerGenomeSTAG1
Protein Interactions : CTDSTAG1
Pharm GKB GenePA36176
PharosQ8WVM7
Clinical trialSTAG1
Miscellaneous
canSAR (ICR)STAG1
HarmonizomeSTAG1
ARCHS4STAG1
DataMed IndexSTAG1
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTAG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 13:01:10 CET 2022

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