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STAM (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1)

Identity

Alias_namessignal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Alias_symbol (synonym)STAM1
Other aliasSTAM-1
HGNC (Hugo) STAM
LocusID (NCBI) 8027
Atlas_Id 74290
Location 10p12.33  [Link to chromosome band 10p12]
Location_base_pair Starts at 17686124 and ends at 17758821 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TMEM127 (2q11.2) / STAM (10p12.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STAM   11357
Cards
Entrez_Gene (NCBI)STAM  8027  signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
AliasesSTAM-1; STAM1
GeneCards (Weizmann)STAM
Ensembl hg19 (Hinxton)ENSG00000136738 [Gene_View]  chr10:17686124-17758821 [Contig_View]  STAM [Vega]
Ensembl hg38 (Hinxton)ENSG00000136738 [Gene_View]  chr10:17686124-17758821 [Contig_View]  STAM [Vega]
ICGC DataPortalENSG00000136738
TCGA cBioPortalSTAM
AceView (NCBI)STAM
Genatlas (Paris)STAM
WikiGenes8027
SOURCE (Princeton)STAM
Genetics Home Reference (NIH)STAM
Genomic and cartography
GoldenPath hg19 (UCSC)STAM  -     chr10:17686124-17758821 +  10p12.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)STAM  -     10p12.33   [Description]    (hg38-Dec_2013)
EnsemblSTAM - 10p12.33 [CytoView hg19]  STAM - 10p12.33 [CytoView hg38]
Mapping of homologs : NCBISTAM [Mapview hg19]  STAM [Mapview hg38]
OMIM601899   
Gene and transcription
Genbank (Entrez)AK024383 AK303083 AK314405 AU118708 BC030586
RefSeq transcript (Entrez)NM_003473
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_008705 NW_004929370
Consensus coding sequences : CCDS (NCBI)STAM
Cluster EST : UnigeneHs.335391 [ NCBI ]
CGAP (NCI)Hs.335391
Alternative Splicing GalleryENSG00000136738
Gene ExpressionSTAM [ NCBI-GEO ]   STAM [ EBI - ARRAY_EXPRESS ]   STAM [ SEEK ]   STAM [ MEM ]
Gene Expression Viewer (FireBrowse)STAM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8027
GTEX Portal (Tissue expression)STAM
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92783   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92783  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92783
Splice isoforms : SwissVarQ92783
PhosPhoSitePlusQ92783
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    UIM (PS50330)    VHS (PS50179)   
Domains : Interpro (EBI)ENTH_VHS    SH3_domain    Ubiquitin-int_motif    VHS    VHS_subgr   
Domain families : Pfam (Sanger)SH3_1 (PF00018)    UIM (PF02809)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam00018    pfam02809    pfam00790   
Domain families : Smart (EMBL)SH3 (SM00326)  UIM (SM00726)  VHS (SM00288)  
Conserved Domain (NCBI)STAM
DMDM Disease mutations8027
Blocks (Seattle)STAM
PDB (SRS)2L0A    3F1I    3LDZ   
PDB (PDBSum)2L0A    3F1I    3LDZ   
PDB (IMB)2L0A    3F1I    3LDZ   
PDB (RSDB)2L0A    3F1I    3LDZ   
Structural Biology KnowledgeBase2L0A    3F1I    3LDZ   
SCOP (Structural Classification of Proteins)2L0A    3F1I    3LDZ   
CATH (Classification of proteins structures)2L0A    3F1I    3LDZ   
SuperfamilyQ92783
Human Protein AtlasENSG00000136738
Peptide AtlasQ92783
HPRD03542
IPIIPI00020178   IPI00607769   IPI01013719   IPI00953321   IPI00854835   
Protein Interaction databases
DIP (DOE-UCLA)Q92783
IntAct (EBI)Q92783
FunCoupENSG00000136738
BioGRIDSTAM
STRING (EMBL)STAM
ZODIACSTAM
Ontologies - Pathways
QuickGOQ92783
Ontology : AmiGOSH3/SH2 adaptor activity  protein binding  cytosol  intracellular protein transport  signal transduction  epidermal growth factor receptor signaling pathway  positive regulation of signal transduction  endosomal transport  early endosome membrane  negative regulation of epidermal growth factor receptor signaling pathway  membrane organization  positive regulation of exosomal secretion  regulation of extracellular exosome assembly  
Ontology : EGO-EBISH3/SH2 adaptor activity  protein binding  cytosol  intracellular protein transport  signal transduction  epidermal growth factor receptor signaling pathway  positive regulation of signal transduction  endosomal transport  early endosome membrane  negative regulation of epidermal growth factor receptor signaling pathway  membrane organization  positive regulation of exosomal secretion  regulation of extracellular exosome assembly  
Pathways : KEGGEndocytosis    Jak-STAT signaling pathway   
NDEx NetworkSTAM
Atlas of Cancer Signalling NetworkSTAM
Wikipedia pathwaysSTAM
Orthology - Evolution
OrthoDB8027
GeneTree (enSembl)ENSG00000136738
Phylogenetic Trees/Animal Genes : TreeFamSTAM
HOVERGENQ92783
HOGENOMQ92783
Homologs : HomoloGeneSTAM
Homology/Alignments : Family Browser (UCSC)STAM
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAM
dbVarSTAM
ClinVarSTAM
1000_GenomesSTAM 
Exome Variant ServerSTAM
ExAC (Exome Aggregation Consortium)STAM (select the gene name)
Genetic variants : HAPMAP8027
Genomic Variants (DGV)STAM [DGVbeta]
DECIPHER (Syndromes)10:17686124-17758821  ENSG00000136738
CONAN: Copy Number AnalysisSTAM 
Mutations
ICGC Data PortalSTAM 
TCGA Data PortalSTAM 
Broad Tumor PortalSTAM
OASIS PortalSTAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTAM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STAM
DgiDB (Drug Gene Interaction Database)STAM
DoCM (Curated mutations)STAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STAM (select a term)
intoGenSTAM
Cancer3DSTAM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601899   
Orphanet
MedgenSTAM
Genetic Testing Registry STAM
NextProtQ92783 [Medical]
TSGene8027
GENETestsSTAM
Huge Navigator STAM [HugePedia]
snp3D : Map Gene to Disease8027
BioCentury BCIQSTAM
ClinGenSTAM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8027
Chemical/Pharm GKB GenePA36179
Clinical trialSTAM
Miscellaneous
canSAR (ICR)STAM (select the gene name)
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTAM
EVEXSTAM
GoPubMedSTAM
iHOPSTAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:46:52 CET 2017

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