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STAM (signal transducing adaptor molecule)

Identity

Alias (NCBI)STAM-1
STAM1
HGNC (Hugo) STAM
HGNC Alias symbSTAM1
HGNC Alias nameHSE1 homolog (S. cerevisiae)
HGNC Previous namesignal transducing adaptor molecule (SH3 domain and ITAM motif) 1
LocusID (NCBI) 8027
Atlas_Id 74290
Location 10p12.33  [Link to chromosome band 10p12]
Location_base_pair Starts at 17644151 and ends at 17716822 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM127 (2q11.2) / STAM (10p12.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)STAM   11357
Cards
Entrez_Gene (NCBI)STAM    signal transducing adaptor molecule
AliasesSTAM-1; STAM1
GeneCards (Weizmann)STAM
Ensembl hg19 (Hinxton)ENSG00000136738 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136738 [Gene_View]  ENSG00000136738 [Sequence]  chr10:17644151-17716822 [Contig_View]  STAM [Vega]
ICGC DataPortalENSG00000136738
TCGA cBioPortalSTAM
AceView (NCBI)STAM
Genatlas (Paris)STAM
SOURCE (Princeton)STAM
Genetics Home Reference (NIH)STAM
Genomic and cartography
GoldenPath hg38 (UCSC)STAM  -     chr10:17644151-17716822 +  10p12.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STAM  -     10p12.33   [Description]    (hg19-Feb_2009)
GoldenPathSTAM - 10p12.33 [CytoView hg19]  STAM - 10p12.33 [CytoView hg38]
ImmunoBaseENSG00000136738
Genome Data Viewer NCBISTAM [Mapview hg19]  
OMIM601899   
Gene and transcription
Genbank (Entrez)AK024383 AK303083 AK314405 AU118708 BC030586
RefSeq transcript (Entrez)NM_001324282 NM_001324283 NM_001324284 NM_001324285 NM_001324286 NM_001324287 NM_001324288 NM_001324289 NM_003473
Consensus coding sequences : CCDS (NCBI)STAM
Gene ExpressionSTAM [ NCBI-GEO ]   STAM [ EBI - ARRAY_EXPRESS ]   STAM [ SEEK ]   STAM [ MEM ]
Gene Expression Viewer (FireBrowse)STAM [ Firebrowse - Broad ]
GenevisibleExpression of STAM in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8027
GTEX Portal (Tissue expression)STAM
Human Protein AtlasENSG00000136738-STAM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92783   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92783  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92783
PhosPhoSitePlusQ92783
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    UIM (PS50330)    VHS (PS50179)   
Domains : Interpro (EBI)ENTH_VHS    SH3-like_dom_sf    SH3_domain    STAM1_SH3    UIM_dom    VHS_dom   
Domain families : Pfam (Sanger)SH3_1 (PF00018)    UIM (PF02809)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam00018    pfam02809    pfam00790   
Domain families : Smart (EMBL)SH3 (SM00326)  VHS (SM00288)  
Conserved Domain (NCBI)STAM
PDB (RSDB)2L0A    3F1I    3LDZ   
PDB Europe2L0A    3F1I    3LDZ   
PDB (PDBSum)2L0A    3F1I    3LDZ   
PDB (IMB)2L0A    3F1I    3LDZ   
Structural Biology KnowledgeBase2L0A    3F1I    3LDZ   
SCOP (Structural Classification of Proteins)2L0A    3F1I    3LDZ   
CATH (Classification of proteins structures)2L0A    3F1I    3LDZ   
SuperfamilyQ92783
AlphaFold pdb e-kbQ92783   
Human Protein Atlas [tissue]ENSG00000136738-STAM [tissue]
HPRD03542
Protein Interaction databases
DIP (DOE-UCLA)Q92783
IntAct (EBI)Q92783
BioGRIDSTAM
STRING (EMBL)STAM
ZODIACSTAM
Ontologies - Pathways
QuickGOQ92783
Ontology : AmiGOprotein binding  cytosol  signal transduction  endosomal transport  macroautophagy  protein deubiquitination  early endosome membrane  ESCRT-0 complex  ESCRT-0 complex  ESCRT-0 complex  phosphatidylinositol binding  multivesicular body assembly  negative regulation of epidermal growth factor receptor signaling pathway  ubiquitin binding  intracellular membrane-bounded organelle  protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  ubiquitin-like protein ligase binding  membrane organization  positive regulation of exosomal secretion  regulation of extracellular exosome assembly  
Ontology : EGO-EBIprotein binding  cytosol  signal transduction  endosomal transport  macroautophagy  protein deubiquitination  early endosome membrane  ESCRT-0 complex  ESCRT-0 complex  ESCRT-0 complex  phosphatidylinositol binding  multivesicular body assembly  negative regulation of epidermal growth factor receptor signaling pathway  ubiquitin binding  intracellular membrane-bounded organelle  protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  ubiquitin-like protein ligase binding  membrane organization  positive regulation of exosomal secretion  regulation of extracellular exosome assembly  
Pathways : KEGGJak-STAT signaling pathway   
NDEx NetworkSTAM
Atlas of Cancer Signalling NetworkSTAM
Wikipedia pathwaysSTAM
Orthology - Evolution
OrthoDB8027
GeneTree (enSembl)ENSG00000136738
Phylogenetic Trees/Animal Genes : TreeFamSTAM
Homologs : HomoloGeneSTAM
Homology/Alignments : Family Browser (UCSC)STAM
Gene fusions - Rearrangements
Fusion : QuiverSTAM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAM
dbVarSTAM
ClinVarSTAM
MonarchSTAM
1000_GenomesSTAM 
Exome Variant ServerSTAM
GNOMAD BrowserENSG00000136738
Varsome BrowserSTAM
ACMGSTAM variants
VarityQ92783
Genomic Variants (DGV)STAM [DGVbeta]
DECIPHERSTAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTAM 
Mutations
ICGC Data PortalSTAM 
TCGA Data PortalSTAM 
Broad Tumor PortalSTAM
OASIS PortalSTAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTAM  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTAM
Mutations and Diseases : HGMDSTAM
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTAM
DgiDB (Drug Gene Interaction Database)STAM
DoCM (Curated mutations)STAM
CIViC (Clinical Interpretations of Variants in Cancer)STAM
Cancer3DSTAM
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601899   
Orphanet
DisGeNETSTAM
MedgenSTAM
Genetic Testing Registry STAM
NextProtQ92783 [Medical]
GENETestsSTAM
Target ValidationSTAM
Huge Navigator STAM [HugePedia]
ClinGenSTAM
Clinical trials, drugs, therapy
MyCancerGenomeSTAM
Protein Interactions : CTDSTAM
Pharm GKB GenePA36179
PharosQ92783
Clinical trialSTAM
Miscellaneous
canSAR (ICR)STAM
HarmonizomeSTAM
DataMed IndexSTAM
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:24:20 CEST 2021

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