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STAR (steroidogenic acute regulatory protein)

Identity

Alias_namessteroidogenic acute regulator
Alias_symbol (synonym)StAR
STARD1
Other alias
HGNC (Hugo) STAR
LocusID (NCBI) 6770
Atlas_Id 42427
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 38142700 and ends at 38151082 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		ELL3 (15q15.3) / STAR (8p11.23)GPI (19q13.11) / STAR (8p11.23)STAR (8p11.23) / MAP7 (6q23.3)
STAR (8p11.23) / STAR (8p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)STAR   11359
Cards
Entrez_Gene (NCBI)STAR  6770  steroidogenic acute regulatory protein
AliasesSTARD1
GeneCards (Weizmann)STAR
Ensembl hg19 (Hinxton)ENSG00000147465 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147465 [Gene_View]  chr8:38142700-38151082 [Contig_View]  STAR [Vega]
ICGC DataPortalENSG00000147465
TCGA cBioPortalSTAR
AceView (NCBI)STAR
Genatlas (Paris)STAR
WikiGenes6770
SOURCE (Princeton)STAR
Genetics Home Reference (NIH)STAR
Genomic and cartography
GoldenPath hg38 (UCSC)STAR  -     chr8:38142700-38151082 -  8p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STAR  -     8p11.23   [Description]    (hg19-Feb_2009)
EnsemblSTAR - 8p11.23 [CytoView hg19]  STAR - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBISTAR [Mapview hg19]  STAR [Mapview hg38]
OMIM201710   600617   
Gene and transcription
Genbank (Entrez)AF035277 AK090513 AK315122 AL526126 AV706111
RefSeq transcript (Entrez)NM_000349 NM_001007243
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STAR
Cluster EST : UnigeneHs.521535 [ NCBI ]
CGAP (NCI)Hs.521535
Alternative Splicing GalleryENSG00000147465
Gene ExpressionSTAR [ NCBI-GEO ]   STAR [ EBI - ARRAY_EXPRESS ]   STAR [ SEEK ]   STAR [ MEM ]
Gene Expression Viewer (FireBrowse)STAR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6770
GTEX Portal (Tissue expression)STAR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49675   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49675  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49675
Splice isoforms : SwissVarP49675
PhosPhoSitePlusP49675
Domaine pattern : Prosite (Expaxy)START (PS50848)   
Domains : Interpro (EBI)StAR    StAR-like    START-like_dom    START_lipid-bd_dom   
Domain families : Pfam (Sanger)START (PF01852)   
Domain families : Pfam (NCBI)pfam01852   
Domain families : Smart (EMBL)START (SM00234)  
Conserved Domain (NCBI)STAR
DMDM Disease mutations6770
Blocks (Seattle)STAR
PDB (SRS)1IMG    2I93    3P0L   
PDB (PDBSum)1IMG    2I93    3P0L   
PDB (IMB)1IMG    2I93    3P0L   
PDB (RSDB)1IMG    2I93    3P0L   
Structural Biology KnowledgeBase1IMG    2I93    3P0L   
SCOP (Structural Classification of Proteins)1IMG    2I93    3P0L   
CATH (Classification of proteins structures)1IMG    2I93    3P0L   
SuperfamilyP49675
Human Protein AtlasENSG00000147465
Peptide AtlasP49675
HPRD02794
IPIIPI00027730   IPI00975605   IPI00977180   IPI00981465   
Protein Interaction databases
DIP (DOE-UCLA)P49675
IntAct (EBI)P49675
FunCoupENSG00000147465
BioGRIDSTAR
STRING (EMBL)STAR
ZODIACSTAR
Ontologies - Pathways
QuickGOP49675
Ontology : AmiGOprotein binding  mitochondrial intermembrane space  cytosol  steroid biosynthetic process  bile acid biosynthetic process  C21-steroid hormone biosynthetic process  estrogen biosynthetic process  brain development  response to nutrient  cholesterol metabolic process  glucocorticoid metabolic process  male gonad development  response to herbicide  response to ionizing radiation  response to lead ion  positive regulation of gene expression  response to activity  cholesterol binding  diterpenoid metabolic process  cholesterol transporter activity  insecticide metabolic process  biphenyl metabolic process  dibenzo-p-dioxin metabolic process  phenol-containing compound metabolic process  phthalate metabolic process  mitochondrial crista  intracellular cholesterol transport  cellular response to insulin stimulus  response to nicotine  cellular response to interferon-alpha  response to drug  response to hydrogen peroxide  circadian sleep/wake cycle, REM sleep  neuron projection  neuronal cell body  negative regulation of neuron apoptotic process  response to estrogen  response to leptin  cellular response to fibroblast growth factor stimulus  response to ethanol  regulation of neuronal synaptic plasticity  positive regulation of neurogenesis  response to corticosterone  response to fungicide  testosterone biosynthetic process  positive regulation of bile acid biosynthetic process  cellular response to lipopolysaccharide  cellular response to antibiotic  cellular response to cadmium ion  cellular response to alkaloid  cellular response to cAMP  cellular response to glucose stimulus  cellular response to interferon-gamma  cellular response to follicle-stimulating hormone stimulus  cellular response to luteinizing hormone stimulus  cellular response to growth hormone stimulus  cellular response to dexamethasone stimulus  cellular response to transforming growth factor beta stimulus  cellular response to epinephrine stimulus  
Ontology : EGO-EBIprotein binding  mitochondrial intermembrane space  cytosol  steroid biosynthetic process  bile acid biosynthetic process  C21-steroid hormone biosynthetic process  estrogen biosynthetic process  brain development  response to nutrient  cholesterol metabolic process  glucocorticoid metabolic process  male gonad development  response to herbicide  response to ionizing radiation  response to lead ion  positive regulation of gene expression  response to activity  cholesterol binding  diterpenoid metabolic process  cholesterol transporter activity  insecticide metabolic process  biphenyl metabolic process  dibenzo-p-dioxin metabolic process  phenol-containing compound metabolic process  phthalate metabolic process  mitochondrial crista  intracellular cholesterol transport  cellular response to insulin stimulus  response to nicotine  cellular response to interferon-alpha  response to drug  response to hydrogen peroxide  circadian sleep/wake cycle, REM sleep  neuron projection  neuronal cell body  negative regulation of neuron apoptotic process  response to estrogen  response to leptin  cellular response to fibroblast growth factor stimulus  response to ethanol  regulation of neuronal synaptic plasticity  positive regulation of neurogenesis  response to corticosterone  response to fungicide  testosterone biosynthetic process  positive regulation of bile acid biosynthetic process  cellular response to lipopolysaccharide  cellular response to antibiotic  cellular response to cadmium ion  cellular response to alkaloid  cellular response to cAMP  cellular response to glucose stimulus  cellular response to interferon-gamma  cellular response to follicle-stimulating hormone stimulus  cellular response to luteinizing hormone stimulus  cellular response to growth hormone stimulus  cellular response to dexamethasone stimulus  cellular response to transforming growth factor beta stimulus  cellular response to epinephrine stimulus  
Pathways : KEGGOvarian steroidogenesis   
NDEx NetworkSTAR
Atlas of Cancer Signalling NetworkSTAR
Wikipedia pathwaysSTAR
Orthology - Evolution
OrthoDB6770
GeneTree (enSembl)ENSG00000147465
Phylogenetic Trees/Animal Genes : TreeFamSTAR
HOVERGENP49675
HOGENOMP49675
Homologs : HomoloGeneSTAR
Homology/Alignments : Family Browser (UCSC)STAR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTAR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STAR
dbVarSTAR
ClinVarSTAR
1000_GenomesSTAR 
Exome Variant ServerSTAR
ExAC (Exome Aggregation Consortium)STAR (select the gene name)
Genetic variants : HAPMAP6770
Genomic Variants (DGV)STAR [DGVbeta]
DECIPHERSTAR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTAR 
Mutations
ICGC Data PortalSTAR 
TCGA Data PortalSTAR 
Broad Tumor PortalSTAR
OASIS PortalSTAR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTAR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTAR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch STAR
DgiDB (Drug Gene Interaction Database)STAR
DoCM (Curated mutations)STAR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STAR (select a term)
intoGenSTAR
Cancer3DSTAR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM201710    600617   
Orphanet3506    21843    21844   
MedgenSTAR
Genetic Testing Registry STAR
NextProtP49675 [Medical]
TSGene6770
GENETestsSTAR
Target ValidationSTAR
Huge Navigator STAR [HugePedia]
snp3D : Map Gene to Disease6770
BioCentury BCIQSTAR
ClinGenSTAR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6770
Chemical/Pharm GKB GenePA36181
Clinical trialSTAR
Miscellaneous
canSAR (ICR)STAR (select the gene name)
Probes
Litterature
PubMed120 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTAR
EVEXSTAR
GoPubMedSTAR
iHOPSTAR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:24 CEST 2017
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