STARD6 (StAR related lipid transfer domain containing 6)

2014-11-01  

Identity

HGNC
STARD6
LOCATION
18q21.2
LOCUSID
147323
ALIAS
-

Other Information

Locus ID:

NCBI: 147323
MIM: 607051
HGNC: 18066
Ensembl: ENSG00000174448

Variants:

dbSNP: 147323
ClinVar: 147323
TCGA: ENSG00000174448
COSMIC: STARD6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174448ENST00000307844P59095
ENSG00000174448ENST00000577499J3QRT9
ENSG00000174448ENST00000581310P59095
ENSG00000174448ENST00000584040J3QRT9

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Metabolism of steroid hormonesREACTOMER-HSA-196071
Pregnenolone biosynthesisREACTOMER-HSA-196108

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
244407592014The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism.4
273400162016STARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism.4
272887852016Genetic association of STARD6 polymorphisms with Alzheimer's disease in a Korean population.1

Citation

Dessen P

STARD6 (StAR related lipid transfer domain containing 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74297/stard6