STARD7 (StAR related lipid transfer domain containing 7)

2016-10-01  

Identity

HGNC
LOCATION
2q11.2
LOCUSID
ALIAS
FAME2,GTT1
FUSION GENES

Other Information

Locus ID:

NCBI: 56910
MIM: 616712
HGNC: 18063
Ensembl: ENSG00000084090

Variants:

dbSNP: 56910
ClinVar: 56910
TCGA: ENSG00000084090
COSMIC: STARD7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000084090ENST00000337288Q9NQZ5
ENSG00000084090ENST00000443962C9JTD3

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PCREACTOMER-HSA-1483191

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
200426132010StarD7 mediates the intracellular trafficking of phosphatidylcholine to mitochondria.34
176729182007Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.17
293018592018PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.12
196793472009Activation of beta-catenin signalling increases StarD7 gene expression in JEG-3 cells.9
273019512016Variations of chromosome 2 gene expressions among patients with lung cancer or non-cancer.9
288218672017Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer.9
293435372018A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7.9
275549722016Suppression of StarD7 promotes endoplasmic reticulum stress and induces ROS production.7
229529072012StarD7 knockdown modulates ABCG2 expression, cell migration, proliferation, and differentiation of human choriocarcinoma JEG-3 cells.6
216225332011StarD7 gene expression in trophoblast cells: contribution of SF-1 and Wnt-beta-catenin signaling.5

Citation

Dessen P

STARD7 (StAR related lipid transfer domain containing 7)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56027/stard7