STC1 (stanniocalcin 1)

2007-02-01  

Identity

HGNC
STC1
LOCATION
8p21.2
LOCUSID
6781
ALIAS
STC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6781
MIM: 601185
HGNC: 11373
Ensembl: ENSG00000159167

Variants:

dbSNP: 6781
ClinVar: 6781
TCGA: ENSG00000159167
COSMIC: STC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159167ENST00000290271P52823
ENSG00000159167ENST00000524323P52823
ENSG00000159167ENST00000524323A0A0H3W641

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
192673252009Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1.89
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
204841062010Stanniocalcin 1 and ovarian tumorigenesis.44
232430222013STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.43
118615082002Overexpression of human stanniocalcin affects growth and reproduction in transgenic mice.32
172727712007Hypoxic preconditioning induces neuroprotective stanniocalcin-1 in brain via IL-6 signaling.32
161097852005Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.31
253912152015STC1 expression is associated with tumor growth and metastasis in breast cancer.31
253735212015Mesenchymal stem cells correct inappropriate epithelial-mesenchyme relation in pulmonary fibrosis using stanniocalcin-1.29
122234802002Characterization of mammalian stanniocalcin receptors. Mitochondrial targeting of ligand and receptor for regulation of cellular metabolism.28

Citation

Dessen P

STC1 (stanniocalcin 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46263/stc1