Atlas of Genetics and Cytogenetics in Oncology and Haematology


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STC2 (stanniocalcin 2)

Identity

Alias (NCBI)STC-2
STCRP
HGNC (Hugo) STC2
HGNC Alias symbSTC-2
LocusID (NCBI) 8614
Atlas_Id 42433
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 173314723 and ends at 173329503 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PLP2 (Xp11.23) / STC2 (5q35.1)STC2 (5q35.1) / RNF11 (1p32.3)STC2 (5q35.1) / STC2 (5q35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)STC2   11374
Cards
Entrez_Gene (NCBI)STC2    stanniocalcin 2
AliasesSTC-2; STCRP
GeneCards (Weizmann)STC2
Ensembl hg19 (Hinxton)ENSG00000113739 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113739 [Gene_View]  ENSG00000113739 [Sequence]  chr5:173314723-173329503 [Contig_View]  STC2 [Vega]
ICGC DataPortalENSG00000113739
TCGA cBioPortalSTC2
AceView (NCBI)STC2
Genatlas (Paris)STC2
SOURCE (Princeton)STC2
Genetics Home Reference (NIH)STC2
Genomic and cartography
GoldenPath hg38 (UCSC)STC2  -     chr5:173314723-173329503 -  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STC2  -     5q35.2   [Description]    (hg19-Feb_2009)
GoldenPathSTC2 - 5q35.2 [CytoView hg19]  STC2 - 5q35.2 [CytoView hg38]
ImmunoBaseENSG00000113739
genome Data Viewer NCBISTC2 [Mapview hg19]  
OMIM603665   
Gene and transcription
Genbank (Entrez)AB012664 AF031036 AF055460 AF098462 AK027390
RefSeq transcript (Entrez)NM_003714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STC2
Alternative Splicing GalleryENSG00000113739
Gene ExpressionSTC2 [ NCBI-GEO ]   STC2 [ EBI - ARRAY_EXPRESS ]   STC2 [ SEEK ]   STC2 [ MEM ]
Gene Expression Viewer (FireBrowse)STC2 [ Firebrowse - Broad ]
GenevisibleExpression of STC2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8614
GTEX Portal (Tissue expression)STC2
Human Protein AtlasENSG00000113739-STC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76061   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76061  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76061
Splice isoforms : SwissVarO76061
PhosPhoSitePlusO76061
Domains : Interpro (EBI)Stanniocalcin   
Domain families : Pfam (Sanger)Stanniocalcin (PF03298)   
Domain families : Pfam (NCBI)pfam03298   
Conserved Domain (NCBI)STC2
Blocks (Seattle)STC2
SuperfamilyO76061
Human Protein Atlas [tissue]ENSG00000113739-STC2 [tissue]
Peptide AtlasO76061
HPRD04717
IPIIPI00008780   IPI00976408   IPI00979765   
Protein Interaction databases
DIP (DOE-UCLA)O76061
IntAct (EBI)O76061
BioGRIDSTC2
STRING (EMBL)STC2
ZODIACSTC2
Ontologies - Pathways
QuickGOO76061
Ontology : AmiGOhormone activity  extracellular space  extracellular space  endoplasmic reticulum  endoplasmic reticulum lumen  cellular calcium ion homeostasis  signal transduction  embryo implantation  negative regulation of gene expression  enzyme binding  heme binding  response to vitamin D  protein homodimerization activity  response to peptide hormone  post-translational protein modification  cellular protein metabolic process  decidualization  regulation of hormone biosynthetic process  perinuclear region of cytoplasm  cellular response to hypoxia  
Ontology : EGO-EBIhormone activity  extracellular space  extracellular space  endoplasmic reticulum  endoplasmic reticulum lumen  cellular calcium ion homeostasis  signal transduction  embryo implantation  negative regulation of gene expression  enzyme binding  heme binding  response to vitamin D  protein homodimerization activity  response to peptide hormone  post-translational protein modification  cellular protein metabolic process  decidualization  regulation of hormone biosynthetic process  perinuclear region of cytoplasm  cellular response to hypoxia  
NDEx NetworkSTC2
Atlas of Cancer Signalling NetworkSTC2
Wikipedia pathwaysSTC2
Orthology - Evolution
OrthoDB8614
GeneTree (enSembl)ENSG00000113739
Phylogenetic Trees/Animal Genes : TreeFamSTC2
HOGENOMO76061
Homologs : HomoloGeneSTC2
Homology/Alignments : Family Browser (UCSC)STC2
Gene fusions - Rearrangements
Fusion : MitelmanSTC2/RNF11 [5q35.1/1p32.3]  
Fusion : QuiverSTC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTC2 [hg38]
dbVarSTC2
ClinVarSTC2
MonarchSTC2
1000_GenomesSTC2 
Exome Variant ServerSTC2
GNOMAD BrowserENSG00000113739
Varsome BrowserSTC2
Genomic Variants (DGV)STC2 [DGVbeta]
DECIPHERSTC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTC2 
Mutations
ICGC Data PortalSTC2 
TCGA Data PortalSTC2 
Broad Tumor PortalSTC2
OASIS PortalSTC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTC2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTC2
Mutations and Diseases : HGMDSTC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STC2
DgiDB (Drug Gene Interaction Database)STC2
DoCM (Curated mutations)STC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STC2 (select a term)
intoGenSTC2
Cancer3DSTC2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603665   
Orphanet
DisGeNETSTC2
MedgenSTC2
Genetic Testing Registry STC2
NextProtO76061 [Medical]
GENETestsSTC2
Target ValidationSTC2
Huge Navigator STC2 [HugePedia]
ClinGenSTC2
Clinical trials, drugs, therapy
MyCancerGenomeSTC2
Protein Interactions : CTD
Pharm GKB GenePA36191
PharosO76061
Clinical trialSTC2
Miscellaneous
canSAR (ICR)STC2 (select the gene name)
HarmonizomeSTC2
DataMed IndexSTC2
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:48:02 CET 2021

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