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STC2 (stanniocalcin 2)

Identity

Alias_symbol (synonym)STC-2
Other aliasSTCRP
HGNC (Hugo) STC2
LocusID (NCBI) 8614
Atlas_Id 42433
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 173314723 and ends at 173329503 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PLP2 (Xp11.23) / STC2 (5q35.1)STC2 (5q35.1) / RNF11 (1p32.3)STC2 (5q35.1) / STC2 (5q35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STC2   11374
Cards
Entrez_Gene (NCBI)STC2  8614  stanniocalcin 2
AliasesSTC-2; STCRP
GeneCards (Weizmann)STC2
Ensembl hg19 (Hinxton)ENSG00000113739 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113739 [Gene_View]  chr5:173314723-173329503 [Contig_View]  STC2 [Vega]
ICGC DataPortalENSG00000113739
TCGA cBioPortalSTC2
AceView (NCBI)STC2
Genatlas (Paris)STC2
WikiGenes8614
SOURCE (Princeton)STC2
Genetics Home Reference (NIH)STC2
Genomic and cartography
GoldenPath hg38 (UCSC)STC2  -     chr5:173314723-173329503 -  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STC2  -     5q35.2   [Description]    (hg19-Feb_2009)
EnsemblSTC2 - 5q35.2 [CytoView hg19]  STC2 - 5q35.2 [CytoView hg38]
Mapping of homologs : NCBISTC2 [Mapview hg19]  STC2 [Mapview hg38]
OMIM603665   
Gene and transcription
Genbank (Entrez)AB012664 AF031036 AF055460 AF098462 AK027390
RefSeq transcript (Entrez)NM_003714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STC2
Cluster EST : UnigeneHs.233160 [ NCBI ]
CGAP (NCI)Hs.233160
Alternative Splicing GalleryENSG00000113739
Gene ExpressionSTC2 [ NCBI-GEO ]   STC2 [ EBI - ARRAY_EXPRESS ]   STC2 [ SEEK ]   STC2 [ MEM ]
Gene Expression Viewer (FireBrowse)STC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8614
GTEX Portal (Tissue expression)STC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76061   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76061  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76061
Splice isoforms : SwissVarO76061
PhosPhoSitePlusO76061
Domains : Interpro (EBI)Stanniocalcin   
Domain families : Pfam (Sanger)Stanniocalcin (PF03298)   
Domain families : Pfam (NCBI)pfam03298   
Conserved Domain (NCBI)STC2
DMDM Disease mutations8614
Blocks (Seattle)STC2
SuperfamilyO76061
Human Protein AtlasENSG00000113739
Peptide AtlasO76061
HPRD04717
IPIIPI00008780   IPI00976408   IPI00979765   
Protein Interaction databases
DIP (DOE-UCLA)O76061
IntAct (EBI)O76061
FunCoupENSG00000113739
BioGRIDSTC2
STRING (EMBL)STC2
ZODIACSTC2
Ontologies - Pathways
QuickGOO76061
Ontology : AmiGOhormone activity  extracellular space  endoplasmic reticulum  Golgi apparatus  cellular calcium ion homeostasis  response to oxidative stress  embryo implantation  negative regulation of gene expression  enzyme binding  heme binding  endoplasmic reticulum unfolded protein response  response to vitamin D  negative regulation of multicellular organism growth  protein homodimerization activity  response to peptide hormone  decidualization  regulation of hormone biosynthetic process  perinuclear region of cytoplasm  cellular response to hypoxia  regulation of store-operated calcium entry  
Ontology : EGO-EBIhormone activity  extracellular space  endoplasmic reticulum  Golgi apparatus  cellular calcium ion homeostasis  response to oxidative stress  embryo implantation  negative regulation of gene expression  enzyme binding  heme binding  endoplasmic reticulum unfolded protein response  response to vitamin D  negative regulation of multicellular organism growth  protein homodimerization activity  response to peptide hormone  decidualization  regulation of hormone biosynthetic process  perinuclear region of cytoplasm  cellular response to hypoxia  regulation of store-operated calcium entry  
NDEx NetworkSTC2
Atlas of Cancer Signalling NetworkSTC2
Wikipedia pathwaysSTC2
Orthology - Evolution
OrthoDB8614
GeneTree (enSembl)ENSG00000113739
Phylogenetic Trees/Animal Genes : TreeFamSTC2
HOVERGENO76061
HOGENOMO76061
Homologs : HomoloGeneSTC2
Homology/Alignments : Family Browser (UCSC)STC2
Gene fusions - Rearrangements
Fusion : MitelmanSTC2/RNF11 [5q35.1/1p32.3]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STC2
dbVarSTC2
ClinVarSTC2
1000_GenomesSTC2 
Exome Variant ServerSTC2
ExAC (Exome Aggregation Consortium)STC2 (select the gene name)
Genetic variants : HAPMAP8614
Genomic Variants (DGV)STC2 [DGVbeta]
DECIPHERSTC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTC2 
Mutations
ICGC Data PortalSTC2 
TCGA Data PortalSTC2 
Broad Tumor PortalSTC2
OASIS PortalSTC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STC2
DgiDB (Drug Gene Interaction Database)STC2
DoCM (Curated mutations)STC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STC2 (select a term)
intoGenSTC2
Cancer3DSTC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603665   
Orphanet
MedgenSTC2
Genetic Testing Registry STC2
NextProtO76061 [Medical]
TSGene8614
GENETestsSTC2
Target ValidationSTC2
Huge Navigator STC2 [HugePedia]
snp3D : Map Gene to Disease8614
BioCentury BCIQSTC2
ClinGenSTC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8614
Chemical/Pharm GKB GenePA36191
Clinical trialSTC2
Miscellaneous
canSAR (ICR)STC2 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTC2
EVEXSTC2
GoPubMedSTC2
iHOPSTC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:27 CEST 2017

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